SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vpu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		4 / 5 ASP A 403
HIS A 407
HIS A 445
HIS A 463
 MN  A 601 ( 2.0A)
MN  A 601 ( 3.2A)
MN  A 602 ( 3.2A)
MN  A 601 ( 3.2A)
 0.37A 1ei6A-5vpuA:
18.5		 1ei6A-5vpuA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_C_PPFC413_1
(PHOSPHONOACETATE
HYDROLASE)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		5 / 8 ASP A  17
ASP A 403
HIS A 407
HIS A 445
HIS A 463
 MN  A 602 ( 2.2A)
MN  A 601 ( 2.0A)
MN  A 601 ( 3.2A)
MN  A 602 ( 3.2A)
MN  A 601 ( 3.2A)
 0.44A 1ei6C-5vpuA:
18.6		 1ei6C-5vpuA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_GLYA1292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		4 / 8 HIS A 445
SER A  67
HIS A 339
ARG A 262
 MN  A 602 ( 3.2A)
MN  A 602 ( 1.8A)
3PG  A 603 (-4.3A)
3PG  A 603 (-3.0A)
 1.29A 1eqbA-5vpuA:
undetectable
1eqbB-5vpuA:
undetectable		 1eqbA-5vpuA:
23.02
1eqbB-5vpuA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_GLYB2292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		4 / 8 HIS A 445
SER A  67
HIS A 339
ARG A 262
 MN  A 602 ( 3.2A)
MN  A 602 ( 1.8A)
3PG  A 603 (-4.3A)
3PG  A 603 (-3.0A)
 1.28A 1eqbA-5vpuA:
undetectable
1eqbB-5vpuA:
undetectable		 1eqbA-5vpuA:
23.02
1eqbB-5vpuA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_GLYC3292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		4 / 8 HIS A 445
SER A  67
HIS A 339
ARG A 262
 MN  A 602 ( 3.2A)
MN  A 602 ( 1.8A)
3PG  A 603 (-4.3A)
3PG  A 603 (-3.0A)
 1.28A 1eqbC-5vpuA:
undetectable
1eqbD-5vpuA:
undetectable		 1eqbC-5vpuA:
23.02
1eqbD-5vpuA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_GLYD4292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		4 / 8 HIS A 445
SER A  67
HIS A 339
ARG A 262
 MN  A 602 ( 3.2A)
MN  A 602 ( 1.8A)
3PG  A 603 (-4.3A)
3PG  A 603 (-3.0A)
 1.28A 1eqbC-5vpuA:
undetectable
1eqbD-5vpuA:
undetectable		 1eqbC-5vpuA:
23.02
1eqbD-5vpuA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F9G_A_ASCA950_0
(HYALURONATE LYASE)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		4 / 7 ARG A 267
TYR A 352
ARG A 330
ARG A 357
 None
 1.42A 1f9gA-5vpuA:
undetectable		 1f9gA-5vpuA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OT7_A_CHCA1001_2
(BILE ACID RECEPTOR)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		4 / 4 MET A 259
MET A 137
ALA A 136
HIS A 133
 None
None
None
EDO  A 607 ( 4.7A)
 1.09A 1ot7A-5vpuA:
0.0		 1ot7A-5vpuA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU3_A_MRCA993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		5 / 12 GLY A 446
ASN A 447
SER A 456
GLN A 450
VAL A 468
 None
 1.35A 1qu3A-5vpuA:
undetectable		 1qu3A-5vpuA:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		4 / 7 MET A 119
ALA A 206
PHE A 258
ARG A 267
 None
 1.39A 1t9wA-5vpuA:
undetectable		 1t9wA-5vpuA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		3 / 3 ASP A 488
ARG A 508
ASP A  56
 None
 0.66A 1vptA-5vpuA:
undetectable		 1vptA-5vpuA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		3 / 3 SER A 456
THR A 464
GLN A 450
 None
 0.79A 2fk8A-5vpuA:
3.1		 2fk8A-5vpuA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		5 / 12 HIS A 407
GLY A  65
HIS A 463
ASP A 403
ASP A  17
 MN  A 601 ( 3.2A)
None
MN  A 601 ( 3.2A)
MN  A 601 ( 2.0A)
MN  A 602 ( 2.2A)
 1.08A 2pgrA-5vpuA:
undetectable		 2pgrA-5vpuA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		4 / 8 PHE A 273
ILE A 269
PHE A 292
GLY A 120
 None
 0.91A 2qwxA-5vpuA:
4.4
2qwxB-5vpuA:
4.5		 2qwxA-5vpuA:
18.57
2qwxB-5vpuA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		4 / 8 PHE A 273
ILE A 269
PHE A 292
GLY A 120
 None
 0.89A 2qx4A-5vpuA:
undetectable
2qx4B-5vpuA:
2.3		 2qx4A-5vpuA:
18.85
2qx4B-5vpuA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_GLYB502_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		4 / 8 HIS A 445
SER A  67
HIS A 339
ARG A 262
 MN  A 602 ( 3.2A)
MN  A 602 ( 1.8A)
3PG  A 603 (-4.3A)
3PG  A 603 (-3.0A)
 1.32A 2vmyA-5vpuA:
undetectable
2vmyB-5vpuA:
undetectable		 2vmyA-5vpuA:
22.91
2vmyB-5vpuA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		4 / 6 HIS A  71
ASP A 197
TYR A 337
HIS A 445
 None
None
None
MN  A 602 ( 3.2A)
 1.47A 3ag1A-5vpuA:
undetectable
3ag1C-5vpuA:
undetectable		 3ag1A-5vpuA:
21.31
3ag1C-5vpuA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		4 / 7 HIS A  71
ASP A 197
TYR A 337
HIS A 445
 None
None
None
MN  A 602 ( 3.2A)
 1.48A 3ag4N-5vpuA:
undetectable
3ag4P-5vpuA:
undetectable		 3ag4N-5vpuA:
21.31
3ag4P-5vpuA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		4 / 8 HIS A 463
HIS A 407
ASP A  17
GLY A  18
 MN  A 601 ( 3.2A)
MN  A 601 ( 3.2A)
MN  A 602 ( 2.2A)
None
 0.89A 3c0zB-5vpuA:
3.7		 3c0zB-5vpuA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		5 / 12 ARG A 243
THR A 186
ILE A 134
ARG A 183
LEU A 150
 None
 1.28A 3iv6C-5vpuA:
4.7		 3iv6C-5vpuA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		5 / 12 GLU A 449
GLY A 406
PHE A 411
ASP A 412
ALA A 413
 None
None
ACT  A 612 (-4.0A)
None
None
 1.18A 3nvkF-5vpuA:
undetectable
3nvkJ-5vpuA:
4.0		 3nvkF-5vpuA:
22.97
3nvkJ-5vpuA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_1
(CYTOCHROME P450 3A4)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		5 / 12 LEU A 142
PHE A 175
ILE A 118
ILE A  91
GLU A 124
 None
 1.04A 3nxuA-5vpuA:
undetectable		 3nxuA-5vpuA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_2
(HIV-1 PROTEASE)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		4 / 7 VAL A 468
GLY A 446
VAL A  69
VAL A  57
 None
 0.84A 3ufnB-5vpuA:
undetectable		 3ufnB-5vpuA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_B_SAMB1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		5 / 12 ASP A 444
GLY A 402
LEU A 467
HIS A  21
GLY A  52
 MN  A 602 (-2.6A)
None
None
None
None
 1.19A 4blvB-5vpuA:
undetectable		 4blvB-5vpuA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		5 / 10 GLY A  77
ASP A 488
GLY A 507
VAL A 489
VAL A 501
 None
 1.30A 4c5nD-5vpuA:
4.9		 4c5nD-5vpuA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		6 / 12 SER A  53
GLY A  52
GLY A  18
GLY A 446
GLY A  65
GLU A 466
 ACT  A 611 (-4.8A)
None
None
None
None
None
 1.21A 4ctkC-5vpuA:
undetectable		 4ctkC-5vpuA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		3 / 3 ASP A 488
ARG A 508
ASP A  56
 None
 0.77A 4fzvA-5vpuA:
2.7		 4fzvA-5vpuA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		5 / 10 ALA A 141
LEU A 140
PHE A  97
ILE A  91
ALA A 307
 None
 1.05A 4j14A-5vpuA:
undetectable		 4j14A-5vpuA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		5 / 11 MET A  64
SER A  53
GLY A  52
ALA A 443
GLY A  70
 None
ACT  A 611 (-4.8A)
None
None
None
 1.11A 4l6v1-5vpuA:
undetectable
4l6v6-5vpuA:
undetectable		 4l6v1-5vpuA:
21.36
4l6v6-5vpuA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		5 / 12 HIS A 463
HIS A 407
GLY A 406
ASP A  17
GLY A  18
 MN  A 601 ( 3.2A)
MN  A 601 ( 3.2A)
None
MN  A 602 ( 2.2A)
None
 1.22A 4lxzA-5vpuA:
3.8		 4lxzA-5vpuA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		5 / 12 HIS A 463
HIS A 407
GLY A 406
ASP A  17
GLY A  18
 MN  A 601 ( 3.2A)
MN  A 601 ( 3.2A)
None
MN  A 602 ( 2.2A)
None
 1.21A 4lxzC-5vpuA:
3.9		 4lxzC-5vpuA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		5 / 12 LEU A 122
ALA A 222
ILE A 134
ILE A 118
ILE A 244
 None
 1.02A 4nkxA-5vpuA:
undetectable		 4nkxA-5vpuA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		4 / 5 ARG A 196
ASP A  17
GLU A  68
VAL A  57
 3PG  A 603 (-3.2A)
MN  A 602 ( 2.2A)
None
None
 1.23A 4nkxC-5vpuA:
undetectable		 4nkxC-5vpuA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_A_ML1A302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		4 / 8 PHE A 273
ILE A 269
PHE A 292
GLY A 120
 None
 0.90A 4qogA-5vpuA:
3.9
4qogB-5vpuA:
4.5		 4qogA-5vpuA:
18.57
4qogB-5vpuA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		6 / 11 ALA A 146
ALA A 141
GLY A 113
GLY A 114
ALA A 109
SER A 255
 None
 1.44A 4qvlK-5vpuA:
undetectable
4qvlL-5vpuA:
undetectable		 4qvlK-5vpuA:
16.70
4qvlL-5vpuA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		6 / 11 ALA A 146
ALA A 141
GLY A 113
GLY A 114
ALA A 109
SER A 255
 None
 1.44A 4qvlY-5vpuA:
undetectable
4qvlZ-5vpuA:
undetectable		 4qvlY-5vpuA:
16.70
4qvlZ-5vpuA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		6 / 10 ALA A 146
ALA A 141
GLY A 113
GLY A 114
ALA A 109
SER A 255
 None
 1.43A 4qvmY-5vpuA:
undetectable
4qvmZ-5vpuA:
undetectable		 4qvmY-5vpuA:
17.56
4qvmZ-5vpuA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		6 / 11 ALA A 146
ALA A 141
GLY A 113
GLY A 114
ALA A 109
SER A 255
 None
 1.43A 4qw1K-5vpuA:
undetectable
4qw1L-5vpuA:
undetectable		 4qw1K-5vpuA:
17.20
4qw1L-5vpuA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_A_1N1A601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		3 / 3 MET A  72
ASP A  83
PHE A  84
 None
None
EDO  A 607 ( 4.7A)
 0.80A 4xeyA-5vpuA:
undetectable		 4xeyA-5vpuA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_B_1N1B601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		3 / 3 MET A  72
ASP A  83
PHE A  84
 None
None
EDO  A 607 ( 4.7A)
 0.81A 4xeyB-5vpuA:
undetectable		 4xeyB-5vpuA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_C_WJZC304_0
(BETA-LACTAMASE NDM-1)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		4 / 7 HIS A 445
GLY A  70
ASN A  66
HIS A 339
 MN  A 602 ( 3.2A)
None
3PG  A 603 (-4.8A)
3PG  A 603 (-4.3A)
 1.21A 5a5zC-5vpuA:
undetectable		 5a5zC-5vpuA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		6 / 11 ALA A 146
ALA A 141
GLY A 113
GLY A 114
ALA A 109
SER A 255
 None
 1.44A 5bxnK-5vpuA:
undetectable
5bxnL-5vpuA:
undetectable		 5bxnK-5vpuA:
16.70
5bxnL-5vpuA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		6 / 11 ALA A 146
ALA A 141
GLY A 113
GLY A 114
ALA A 109
SER A 255
 None
 1.45A 5bxnY-5vpuA:
undetectable
5bxnZ-5vpuA:
undetectable		 5bxnY-5vpuA:
16.70
5bxnZ-5vpuA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		4 / 5 GLY A 120
GLU A 131
HIS A 130
ASP A 155
 None
None
EDO  A 607 (-3.8A)
None
 1.22A 5c0oH-5vpuA:
4.5		 5c0oH-5vpuA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		4 / 8 ASP A 264
GLU A 335
ASP A 195
TYR A 191
 3PG  A 603 ( 4.9A)
EDO  A 604 (-2.8A)
None
None
 0.96A 5cfsA-5vpuA:
undetectable		 5cfsA-5vpuA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		4 / 6 PHE A 153
SER A 129
MET A 194
LEU A 122
 None
 1.47A 5dzka-5vpuA:
undetectable
5dzko-5vpuA:
undetectable		 5dzka-5vpuA:
17.94
5dzko-5vpuA:
1.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_1
(DIHYDROFOLATE
REDUCTASE)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		3 / 3 ASP A 369
ARG A 265
ARG A 202
 None
EDO  A 604 ( 2.8A)
EDO  A 604 ( 4.8A)
 0.92A 5eajB-5vpuA:
1.7		 5eajB-5vpuA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF8_A_LBHA2004_1
(HDAC6 PROTEIN)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		5 / 12 ASP A 195
ASP A 444
HIS A  71
PHE A 343
ASP A  17
 None
MN  A 602 (-2.6A)
None
None
MN  A 602 ( 2.2A)
 1.33A 5ef8A-5vpuA:
3.0		 5ef8A-5vpuA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		5 / 12 GLY A 189
MET A 194
GLY A 125
SER A 123
LEU A 168
 None
 0.91A 5gwxA-5vpuA:
3.9		 5gwxA-5vpuA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		3 / 3 HIS A  71
HIS A 339
ARG A 262
 None
3PG  A 603 (-4.3A)
3PG  A 603 (-3.0A)
 1.04A 6b58A-5vpuA:
undetectable		 6b58A-5vpuA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		5 / 12 LEU A 295
ASN A 260
PHE A 261
ASP A 158
GLY A 126
 None
None
None
3PG  A 603 (-2.4A)
None
 1.07A 6dwnA-5vpuA:
undetectable		 6dwnA-5vpuA:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GH9_A_MIXA1003_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		4 / 5 ASN A  66
GLY A 120
HIS A 128
ASP A 264
 3PG  A 603 (-4.8A)
None
3PG  A 603 (-3.9A)
3PG  A 603 ( 4.9A)
 1.15A 6gh9A-5vpuA:
undetectable		 6gh9A-5vpuA:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		5 / 10 GLY A 484
ALA A 487
LEU A 486
GLY A  52
LEU A 359
 None
 1.21A 6hqbA-5vpuA:
undetectable
6hqbJ-5vpuA:
undetectable		 6hqbA-5vpuA:
10.89
6hqbJ-5vpuA:
5.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		5 / 12 LEU A 121
GLY A 120
ASP A 264
ILE A 302
SER A 129
 None
None
3PG  A 603 ( 4.9A)
None
None
 1.13A 6mhtA-5vpuA:
undetectable		 6mhtA-5vpuA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_E_LLLE301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Acinetobacter
baumannii) 		4 / 7 ASP A 201
ARG A 199
ASP A 197
GLU A 335
 EDO  A 609 (-4.1A)
None
None
EDO  A 604 (-2.8A)
 1.24A 6mn5E-5vpuA:
undetectable		 6mn5E-5vpuA:
10.83