SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vqd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_A_CHDA1150_1
(ALCOHOL
DEHYDROGENASE)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		4 / 4 GLU A 269
MET A 262
LEU A 266
SER A 267
 None
 0.93A 1ee2B-5vqdA:
1.7		 1ee2B-5vqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1501_0
(FERROCHELATASE)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		5 / 12 ILE A   5
LEU A 359
PRO A 360
VAL A  21
TRP A  20
 None
 1.13A 1hrkA-5vqdA:
3.3		 1hrkA-5vqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_G_AG2G7003_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		4 / 6 ASP A 314
GLY A 283
ILE A   5
ARG A 276
 None
 0.85A 1mt1G-5vqdA:
0.0
1mt1J-5vqdA:
undetectable		 1mt1G-5vqdA:
22.50
1mt1J-5vqdA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_1
(MODIFICATION
METHYLASE RSRI)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		3 / 3 ASP A 198
HIS A 206
ASP A 288
 None
None
GOL  A 601 (-2.9A)
 0.87A 1nw5A-5vqdA:
undetectable		 1nw5A-5vqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_D_DEXD4999_2
(GLUCOCORTICOID
RECEPTOR)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		4 / 5 LEU A 469
MET A 545
LEU A 544
GLN A 399
 None
 1.26A 1p93D-5vqdA:
undetectable		 1p93D-5vqdA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVT_A_PRLA311_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		4 / 8 LEU A  79
THR A 319
ILE A  42
TYR A  64
 None
 1.07A 1qvtA-5vqdA:
undetectable		 1qvtA-5vqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		5 / 12 GLY A 136
ILE A  89
THR A 144
GLU A  94
PRO A  66
 None
 1.19A 1sg9A-5vqdA:
undetectable		 1sg9A-5vqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAK_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		5 / 12 LEU A 405
SER A 406
PRO A 407
GLN A 408
GLY A 546
 None
 0.93A 1uakA-5vqdA:
undetectable		 1uakA-5vqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAK_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		5 / 12 LEU A 405
SER A 406
PRO A 407
GLN A 408
ILE A 413
 None
 0.74A 1uakA-5vqdA:
undetectable		 1uakA-5vqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		4 / 7 PHE A 476
ASN A 420
ASN A 161
HIS A 516
 None
 1.38A 1wu8A-5vqdA:
undetectable
1wu8C-5vqdA:
undetectable		 1wu8A-5vqdA:
15.12
1wu8C-5vqdA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_2
(POL POLYPROTEIN)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		6 / 12 GLY A 115
ALA A 118
ASP A 120
GLY A 166
PRO A 558
VAL A 395
 None
None
GOL  A 602 ( 4.8A)
None
None
None
 1.48A 2avoB-5vqdA:
undetectable		 2avoB-5vqdA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BPX_B_MK1B902_2
(HIV-1 PROTEASE)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		6 / 12 GLY A 115
ALA A 118
ASP A 120
GLY A 166
PRO A 558
VAL A 395
 None
None
GOL  A 602 ( 4.8A)
None
None
None
 1.45A 2bpxB-5vqdA:
undetectable		 2bpxB-5vqdA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		3 / 3 THR A 144
PRO A 147
TYR A 179
 None
 0.98A 2dxrA-5vqdA:
undetectable		 2dxrA-5vqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA701_0
(FERROCHELATASE)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		5 / 12 ILE A   5
LEU A 359
PRO A 360
VAL A  21
TRP A  20
 None
 1.15A 2hrcA-5vqdA:
undetectable		 2hrcA-5vqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1605_0
(FERROCHELATASE)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		5 / 12 ILE A   5
LEU A 359
PRO A 360
VAL A  21
TRP A  20
 None
 1.14A 2hrcB-5vqdA:
3.4		 2hrcB-5vqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1003_0
(ALDEHYDE
DEHYDROGENASE A)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		4 / 5 ILE A 460
LEU A 463
ASP A 495
PHE A 448
 None
 0.80A 2opxA-5vqdA:
undetectable		 2opxA-5vqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		5 / 12 ILE A   5
LEU A 359
PRO A 360
VAL A  21
TRP A  20
 None
 1.19A 2po7A-5vqdA:
3.3		 2po7A-5vqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		4 / 8 ARG A 203
PRO A 263
SER A 265
VAL A 211
 None
 1.14A 2qd2A-5vqdA:
3.4		 2qd2A-5vqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA501_0
(FERROCHELATASE)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		5 / 11 LEU A 284
LEU A  88
ILE A   5
VAL A  21
TRP A  20
 None
 1.31A 2qd3A-5vqdA:
2.8		 2qd3A-5vqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA501_0
(FERROCHELATASE)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		5 / 11 MET A 315
LEU A  88
ILE A   5
VAL A  21
TRP A  20
 None
 1.32A 2qd3A-5vqdA:
2.8		 2qd3A-5vqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		4 / 6 ILE A 256
ARG A 250
PRO A 196
SER A 240
 None
 1.16A 2qd3B-5vqdA:
2.6		 2qd3B-5vqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		4 / 5 PHE A 434
PHE A 508
SER A 496
PHE A 511
 None
 1.16A 2v0mD-5vqdA:
undetectable		 2v0mD-5vqdA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y04_B_68HB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		5 / 12 THR A 419
VAL A 416
PHE A 476
SER A 496
PHE A 508
 None
 1.27A 2y04B-5vqdA:
undetectable		 2y04B-5vqdA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		5 / 12 ASN A 161
ALA A 111
GLY A 100
ILE A 485
THR A 419
 None
 1.07A 3c6gA-5vqdA:
undetectable		 3c6gA-5vqdA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		5 / 12 LEU A  87
LEU A  88
LEU A 189
LEU A 284
MET A 315
 None
 1.33A 3d90B-5vqdA:
undetectable		 3d90B-5vqdA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		4 / 7 ARG A 203
PRO A 263
SER A 265
VAL A 211
 None
 1.19A 4klrA-5vqdA:
3.2		 4klrA-5vqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		4 / 5 THR A 164
THR A 160
ASP A 150
TYR A 223
 None
 1.37A 4oltA-5vqdA:
undetectable		 4oltA-5vqdA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		4 / 5 THR A 164
THR A 160
ASP A 150
TYR A 223
 None
 1.36A 4qwpB-5vqdA:
undetectable		 4qwpB-5vqdA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		4 / 6 TYR A 179
GLY A  97
GLU A 135
ASP A 106
 None
 1.31A 5emlA-5vqdA:
5.8		 5emlA-5vqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		5 / 12 ALA A 111
SER A 532
ALA A 384
LEU A 385
SER A 391
 None
 1.36A 5jglA-5vqdA:
undetectable		 5jglA-5vqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		5 / 8 ILE A 149
THR A 190
ALA A 235
LEU A 238
THR A 237
 None
 0.89A 5og9A-5vqdA:
undetectable		 5og9A-5vqdA:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BTX_A_EDTA503_0
(SOLUTE CARRIER
FAMILY 39
(IRON-REGULATED
TRANSPORTER))		 5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX
(unidentified) 		4 / 7 SER A 512
SER A 112
GLY A 115
ARG A  95
 None
 1.10A 6btxA-5vqdA:
0.9		 6btxA-5vqdA:
undetectable