SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vqj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5vqj EXO-BETA-1,4-XYLANAS
E
(unidentified) 		4 / 7 TYR A  80
TYR A 194
GLY A  51
THR A  20
 None
 0.87A 2g70A-5vqjA:
undetectable		 2g70A-5vqjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5vqj EXO-BETA-1,4-XYLANAS
E
(unidentified) 		4 / 7 TYR A  80
TYR A 194
GLY A  51
THR A  20
 None
 0.83A 2g70B-5vqjA:
undetectable		 2g70B-5vqjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_0
(O-METHYLTRANSFERASE)		 5vqj EXO-BETA-1,4-XYLANAS
E
(unidentified) 		5 / 12 PHE A  18
LEU A   5
GLY A  51
GLY A  52
ASP A 191
 None
 1.13A 3i5uA-5vqjA:
undetectable		 3i5uA-5vqjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 5vqj EXO-BETA-1,4-XYLANAS
E
(unidentified) 		5 / 12 TYR A 126
GLN A 103
LYS A 171
ALA A 172
ASN A 122
 None
 1.23A 3qowA-5vqjA:
undetectable		 3qowA-5vqjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5vqj EXO-BETA-1,4-XYLANAS
E
(unidentified) 		5 / 12 TRP A  82
TYR A 100
PRO A 137
TRP A 149
TYR A 194
 None
 0.38A 5tzoA-5vqjA:
24.0		 5tzoA-5vqjA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5vqj EXO-BETA-1,4-XYLANAS
E
(unidentified) 		5 / 12 VAL A  50
TRP A  82
TYR A 100
PRO A 137
TRP A 149
 None
 0.67A 5tzoA-5vqjA:
24.0		 5tzoA-5vqjA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5vqj EXO-BETA-1,4-XYLANAS
E
(unidentified) 		4 / 8 TYR A 129
ARG A 133
GLN A 147
TRP A 149
 None
 0.94A 5tzoB-5vqjA:
24.0		 5tzoB-5vqjA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5vqj EXO-BETA-1,4-XYLANAS
E
(unidentified) 		5 / 12 TRP A  82
TYR A 100
PRO A 137
TRP A 149
TYR A 194
 None
 0.39A 5tzoC-5vqjA:
23.9		 5tzoC-5vqjA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5vqj EXO-BETA-1,4-XYLANAS
E
(unidentified) 		5 / 12 VAL A  50
TRP A  82
TYR A 100
PRO A 137
TRP A 149
 None
 0.71A 5tzoC-5vqjA:
23.9		 5tzoC-5vqjA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5vqj EXO-BETA-1,4-XYLANAS
E
(unidentified) 		4 / 8 TYR A 129
ARG A 133
GLN A 147
TRP A 149
 None
 1.05A 5tzoC-5vqjA:
23.9		 5tzoC-5vqjA:
17.55