SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vqm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 5vqm PA41 FAB HEAVY CHAIN
(Homo
sapiens) 		4 / 8 ASP H 107
SER H  99
ARG H  98
PRO H 104
 None
 0.92A 4uhxA-5vqmH:
undetectable		 4uhxA-5vqmH:
5.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 5vqm PA41 FAB HEAVY CHAIN
(Homo
sapiens) 		4 / 8 ASP H 107
SER H  99
ARG H  98
PRO H 104
 None
 0.92A 4uhxA-5vqmH:
undetectable		 4uhxA-5vqmH:
5.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA606_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5vqm PA41 FAB HEAVY CHAIN
(Homo
sapiens) 		4 / 5 GLU H 154
PHE H 152
HIS H 206
THR H 116
 None
 1.01A 6b58A-5vqmH:
undetectable		 6b58A-5vqmH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 5vqm PA41 FAB HEAVY CHAIN
(Homo
sapiens) 		4 / 7 ALA H  57
GLY H  56
GLY H  49
ASN H  52
 None
 0.76A 6nm4A-5vqmH:
undetectable		 6nm4A-5vqmH:
undetectable