SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vst'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_B_LOCB502_1
(TUBULIN BETA CHAIN)		 5vst BILIARY GLYCOPROTEIN
(Mus
musculus) 		5 / 12 LEU A  20
THR A  98
ALA A 100
VAL A 102
ILE A  88
 NAG  A 301 (-4.8A)
None
None
None
None
 0.97A 4x20B-5vstA:
undetectable		 4x20B-5vstA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 5vst BILIARY GLYCOPROTEIN
(Mus
musculus) 		4 / 5 PRO A 109
VAL A 186
GLY A  84
VAL A  78
 None
 1.02A 6ak3B-5vstA:
undetectable		 6ak3B-5vstA:
18.88