SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vt8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3O_A_DLUA399_1
(PFV INTEGRASE)		 5vt8 CADHERIN-23
(Mus
musculus) 		4 / 7 ASP B2618
ASP B2580
TYR B2496
GLN B2549
 CA  B2801 ( 3.2A)
CA  B2801 (-2.9A)
None
None
 1.27A 3s3oA-5vt8B:
undetectable		 3s3oA-5vt8B:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5vt8 CADHERIN-23
(Mus
musculus) 		3 / 3 GLN B2545
THR B2544
THR B2543
 None
 0.68A 4fu9A-5vt8B:
undetectable		 4fu9A-5vt8B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5vt8 CADHERIN-23
(Mus
musculus) 		3 / 3 GLN B2545
THR B2544
THR B2543
 None
 0.66A 4fufA-5vt8B:
undetectable		 4fufA-5vt8B:
undetectable