SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vt9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_A_ID2A1_0
(THYMIDINE KINASE)		 5vt9 MYOSIN LIGHT CHAIN
TGMLC1
MYOSIN-A
(Toxoplasma
gondii;
Toxoplasma
gondii) 		5 / 12 ILE C 806
ILE A 173
TYR A 177
ALA A 155
TYR A 156
 None
 1.46A 1ki7A-5vt9C:
undetectable		 1ki7A-5vt9C:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 5vt9 MYOSIN LIGHT CHAIN
TGMLC1
(Toxoplasma
gondii) 		4 / 7 ILE A 199
LEU A 174
GLY A 171
TYR A 177
 None
 0.86A 2tsrA-5vt9A:
undetectable		 2tsrA-5vt9A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 5vt9 MYOSIN LIGHT CHAIN
TGMLC1
MYOSIN-A
(Toxoplasma
gondii;
Toxoplasma
gondii) 		3 / 3 ASP A 116
SER A 113
ARG C 808
 None
 0.85A 3loqA-5vt9A:
undetectable		 3loqA-5vt9A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 5vt9 MYOSIN LIGHT CHAIN
TGMLC1
(Toxoplasma
gondii) 		4 / 7 ILE A 199
LEU A 174
GLY A 171
TYR A 177
 None
 0.83A 4iqqC-5vt9A:
undetectable		 4iqqC-5vt9A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_2
(CYTOCHROME P450 3A4)		 5vt9 MYOSIN-A
(Toxoplasma
gondii) 		3 / 3 ARG C 814
ARG C 808
ARG C 815
 None
 1.02A 5vcgA-5vt9C:
undetectable		 5vcgA-5vt9C:
6.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 5vt9 MYOSIN LIGHT CHAIN
TGMLC1
(Toxoplasma
gondii) 		4 / 7 ILE A 199
LEU A 174
GLY A 171
TYR A 177
 None
 0.86A 5x5qC-5vt9A:
undetectable		 5x5qC-5vt9A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 5vt9 MYOSIN LIGHT CHAIN
TGMLC1
(Toxoplasma
gondii) 		4 / 8 ILE A 199
LEU A 174
GLY A 171
TYR A 177
 None
 0.87A 5x5qF-5vt9A:
undetectable		 5x5qF-5vt9A:
21.02