SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vta'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 5vta FAB HEAVY CHAIN
(Mus
musculus) 		5 / 12 LEU H   4
GLY H 107
MET H  37
PHE H 102
VAL H  93
 None
 1.44A 2w8yA-5vtaH:
undetectable		 2w8yA-5vtaH:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5vta FAB HEAVY CHAIN
(Mus
musculus) 		5 / 12 VAL H 166
VAL H 185
SER H 183
ASN H 200
ASN H 158
 None
 1.44A 2y03A-5vtaH:
undetectable		 2y03A-5vtaH:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5vta FAB HEAVY CHAIN
(Mus
musculus) 		5 / 12 VAL H 166
VAL H 185
SER H 183
ASN H 200
ASN H 158
 None
 1.48A 2y03B-5vtaH:
undetectable		 2y03B-5vtaH:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 5vta FAB HEAVY CHAIN
(Mus
musculus) 		5 / 10 VAL H 166
VAL H 185
SER H 183
ASN H 200
ASN H 158
 None
 1.48A 4ldoA-5vtaH:
undetectable		 4ldoA-5vtaH:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)		 5vta FAB HEAVY CHAIN
(Mus
musculus) 		3 / 3 PRO H 188
SER H 190
SER H 191
 None
 0.52A 6bpyA-5vtaH:
undetectable		 6bpyA-5vtaH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 5vta FAB HEAVY CHAIN
(Mus
musculus) 		5 / 12 VAL H 166
VAL H 185
SER H 183
ASN H 200
ASN H 158
 None
 1.44A 6h7mB-5vtaH:
undetectable		 6h7mB-5vtaH:
15.48