SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vtg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 5vtg TRANSLOCATION AND
ASSEMBLY MODULE
SUBUNIT TAMB
(Escherichia
coli) 		4 / 7 LEU A1053
VAL A1034
GLY A1051
ILE A1040
 None
 0.80A 1p2yA-5vtgA:
undetectable		 1p2yA-5vtgA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 5vtg TRANSLOCATION AND
ASSEMBLY MODULE
SUBUNIT TAMB
(Escherichia
coli) 		5 / 12 LEU A1045
ILE A 991
ALA A1125
LEU A1089
LEU A1053
 None
 1.42A 3vw1B-5vtgA:
undetectable		 3vw1B-5vtgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_C_SFYC804_0
(SEPIAPTERIN
REDUCTASE)		 5vtg TRANSLOCATION AND
ASSEMBLY MODULE
SUBUNIT TAMB
(Escherichia
coli) 		5 / 12 LEU A1100
LEU A1064
PRO A1094
GLN A1097
ALA A1125
 None
 1.47A 4hwkC-5vtgA:
undetectable		 4hwkC-5vtgA:
undetectable