SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vu3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5vu3 COMPETENCE
DAMAGE-INDUCIBLE
PROTEIN A
(Enterobacter
cloacae) 		5 / 12 VAL A 151
SER A 159
PHE A 129
ILE A 109
GLY A 111
 None
 1.05A 3kk6B-5vu3A:
undetectable		 3kk6B-5vu3A:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 5vu3 COMPETENCE
DAMAGE-INDUCIBLE
PROTEIN A
(Enterobacter
cloacae) 		5 / 12 ALA A 103
VAL A 164
LEU A  24
LEU A  42
LEU A  46
 None
 1.07A 4qzuC-5vu3A:
undetectable		 4qzuC-5vu3A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5vu3 COMPETENCE
DAMAGE-INDUCIBLE
PROTEIN A
(Enterobacter
cloacae) 		4 / 6 GLU A 119
GLY A 118
GLY A 121
ASP A 120
 None
 1.04A 5a06D-5vu3A:
undetectable		 5a06D-5vu3A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 5vu3 COMPETENCE
DAMAGE-INDUCIBLE
PROTEIN A
(Enterobacter
cloacae) 		4 / 6 VAL A 151
LYS A 154
ALA A 155
VAL A 127
 None
 0.88A 5i8fA-5vu3A:
undetectable		 5i8fA-5vu3A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA608_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5vu3 COMPETENCE
DAMAGE-INDUCIBLE
PROTEIN A
(Enterobacter
cloacae) 		3 / 3 GLY A  59
THR A  33
GLU A  35
 None
 0.63A 6b58A-5vu3A:
undetectable		 6b58A-5vu3A:
13.07