SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vvh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 5vvh OCTOPINE
CATABOLISM/UPTAKE
OPERON REGULATORY
PROTEIN OCCR
(Agrobacterium
tumefaciens) 		4 / 6 ILE A 143
ARG A 266
TRP A 284
VAL A 122
 None
 0.78A 1db1A-5vvhA:
undetectable		 1db1A-5vvhA:
25.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5vvh OCTOPINE
CATABOLISM/UPTAKE
OPERON REGULATORY
PROTEIN OCCR
(Agrobacterium
tumefaciens) 		4 / 7 ILE A 210
PRO A 182
PHE A 254
ALA A 206
 None
 1.08A 1oniG-5vvhA:
undetectable
1oniI-5vvhA:
undetectable		 1oniG-5vvhA:
22.86
1oniI-5vvhA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5vvh OCTOPINE
CATABOLISM/UPTAKE
OPERON REGULATORY
PROTEIN OCCR
(Agrobacterium
tumefaciens) 		4 / 6 ILE A 234
GLY A 233
ALA A 232
HIS A 172
 None
 0.91A 1wmqA-5vvhA:
undetectable		 1wmqA-5vvhA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5vvh OCTOPINE
CATABOLISM/UPTAKE
OPERON REGULATORY
PROTEIN OCCR
(Agrobacterium
tumefaciens) 		4 / 6 ILE A 234
GLY A 233
ALA A 232
HIS A 172
 None
 0.91A 1wmqB-5vvhA:
undetectable		 1wmqB-5vvhA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5vvh OCTOPINE
CATABOLISM/UPTAKE
OPERON REGULATORY
PROTEIN OCCR
(Agrobacterium
tumefaciens) 		4 / 6 ILE A 234
GLY A 233
ALA A 232
HIS A 172
 None
 0.91A 1wpuA-5vvhA:
undetectable		 1wpuA-5vvhA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5vvh OCTOPINE
CATABOLISM/UPTAKE
OPERON REGULATORY
PROTEIN OCCR
(Agrobacterium
tumefaciens) 		4 / 6 ILE A 234
GLY A 233
ALA A 232
HIS A 172
 None
 0.90A 1wpuB-5vvhA:
undetectable		 1wpuB-5vvhA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5vvh OCTOPINE
CATABOLISM/UPTAKE
OPERON REGULATORY
PROTEIN OCCR
(Agrobacterium
tumefaciens) 		4 / 6 ILE A 234
GLY A 233
ALA A 232
HIS A 172
 None
 0.87A 1wrqA-5vvhA:
undetectable		 1wrqA-5vvhA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5vvh OCTOPINE
CATABOLISM/UPTAKE
OPERON REGULATORY
PROTEIN OCCR
(Agrobacterium
tumefaciens) 		4 / 6 ILE A 234
GLY A 233
ALA A 232
HIS A 172
 None
 0.88A 1wrqB-5vvhA:
undetectable		 1wrqB-5vvhA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_H_RBFH200_1
(DODECIN)		 5vvh OCTOPINE
CATABOLISM/UPTAKE
OPERON REGULATORY
PROTEIN OCCR
(Agrobacterium
tumefaciens) 		4 / 8 GLN A 293
ARG A 108
GLN A 112
ARG A 285
 None
 1.42A 2vxaB-5vvhA:
undetectable
2vxaG-5vvhA:
undetectable
2vxaH-5vvhA:
undetectable		 2vxaB-5vvhA:
15.42
2vxaG-5vvhA:
15.42
2vxaH-5vvhA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 5vvh OCTOPINE
CATABOLISM/UPTAKE
OPERON REGULATORY
PROTEIN OCCR
(Agrobacterium
tumefaciens) 		4 / 5 VAL A 165
VAL A 166
PHE A 257
ARG A 212
 None
 1.30A 3bjwB-5vvhA:
undetectable		 3bjwB-5vvhA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5vvh OCTOPINE
CATABOLISM/UPTAKE
OPERON REGULATORY
PROTEIN OCCR
(Agrobacterium
tumefaciens) 		5 / 12 PHE A 257
PRO A 182
LEU A 185
ILE A 207
ALA A 164
 None
 1.42A 4a83A-5vvhA:
undetectable		 4a83A-5vvhA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)		 5vvh OCTOPINE
CATABOLISM/UPTAKE
OPERON REGULATORY
PROTEIN OCCR
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 162
MET A 297
LEU A 225
ALA A 100
LEU A 105
 None
 1.17A 5ienB-5vvhA:
undetectable		 5ienB-5vvhA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 5vvh OCTOPINE
CATABOLISM/UPTAKE
OPERON REGULATORY
PROTEIN OCCR
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 227
GLY A 233
GLN A 193
VAL A 203
ILE A 236
 None
 1.47A 6bxnB-5vvhA:
2.3		 6bxnB-5vvhA:
23.85