SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vx5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 5vx5 OUTER CAPSID PROTEIN
VP4
(Rotavirus
A) 		4 / 8 TRP A 102
SER A  99
ASN A  98
THR A 190
 None
 1.02A 1ig3A-5vx5A:
undetectable
1ig3B-5vx5A:
undetectable		 1ig3A-5vx5A:
undetectable
1ig3B-5vx5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)		 5vx5 OUTER CAPSID PROTEIN
VP4
(Rotavirus
A) 		4 / 6 THR A 175
GLY A 165
ILE A  84
LEU A 157
 None
 0.95A 4ac9C-5vx5A:
undetectable		 4ac9C-5vx5A:
undetectable