SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vxb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 5vxb PROXP-ALA
(Caulobacter
vibrioides) 		4 / 7 THR A  65
ALA A 102
ASN A  46
LEU A 145
 None
 1.05A 2hzqA-5vxbA:
undetectable		 2hzqA-5vxbA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 5vxb PROXP-ALA
(Caulobacter
vibrioides) 		4 / 5 PHE A 129
PHE A 103
PHE A  11
VAL A 127
 None
 1.04A 2lh6A-5vxbA:
undetectable		 2lh6A-5vxbA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5vxb PROXP-ALA
(Caulobacter
vibrioides) 		4 / 8 LEU A 152
VAL A  95
GLY A  94
MET A   1
 None
 0.99A 2po5A-5vxbA:
undetectable		 2po5A-5vxbA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5vxb PROXP-ALA
(Caulobacter
vibrioides) 		5 / 9 LEU A 152
LEU A  58
VAL A  95
GLY A  94
MET A   1
 None
 1.14A 2po7A-5vxbA:
0.0		 2po7A-5vxbA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5vxb PROXP-ALA
(Caulobacter
vibrioides) 		5 / 9 LEU A 152
LEU A  58
VAL A  95
GLY A  94
MET A   1
 None
 1.14A 2po7B-5vxbA:
0.0		 2po7B-5vxbA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_D_X2ND1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 5vxb PROXP-ALA
(Caulobacter
vibrioides) 		5 / 12 ILE A  67
PHE A 148
ALA A   9
ALA A   5
LEU A 132
 None
 1.39A 2x2nD-5vxbA:
undetectable		 2x2nD-5vxbA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 5vxb PROXP-ALA
(Caulobacter
vibrioides) 		5 / 12 PRO A 156
LEU A 149
GLY A  63
PHE A 129
THR A  65
 None
 1.23A 4mubA-5vxbA:
undetectable		 4mubA-5vxbA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 5vxb PROXP-ALA
(Caulobacter
vibrioides) 		3 / 3 PHE A 115
THR A 137
LEU A 121
 None
 0.75A 4qztA-5vxbA:
undetectable		 4qztA-5vxbA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALC_L_TIQL1210_2
(ANTI-TICAGRELOR FAB
72, LIGHT CHAIN)		 5vxb PROXP-ALA
(Caulobacter
vibrioides) 		4 / 8 SER A 124
GLY A  42
ILE A  59
GLY A  63
 None
 0.84A 5alcL-5vxbA:
undetectable		 5alcL-5vxbA:
21.49