SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vxv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_B_SFYB806_0
(SEPIAPTERIN
REDUCTASE)		 5vxv PEROXISOMAL MEMBRANE
PROTEIN PEX15
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 242
SER A 223
CYH A 216
TRP A 213
TYR A 212
 None
 1.30A 4hwkB-5vxvA:
undetectable		 4hwkB-5vxvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_C_SFYC804_0
(SEPIAPTERIN
REDUCTASE)		 5vxv PEROXISOMAL MEMBRANE
PROTEIN PEX15
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 242
SER A 223
CYH A 216
TRP A 213
TYR A 212
 None
 1.31A 4hwkC-5vxvA:
undetectable		 4hwkC-5vxvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_D_SFYD803_0
(SEPIAPTERIN
REDUCTASE)		 5vxv PEROXISOMAL MEMBRANE
PROTEIN PEX15
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 242
SER A 223
CYH A 216
TRP A 213
TYR A 212
 None
 1.35A 4hwkD-5vxvA:
undetectable		 4hwkD-5vxvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_J_SASJ804_1
(SEPIAPTERIN
REDUCTASE)		 5vxv PEROXISOMAL MEMBRANE
PROTEIN PEX15
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 242
SER A 223
CYH A 216
TRP A 213
TYR A 212
 None
 1.31A 4j7xJ-5vxvA:
undetectable		 4j7xJ-5vxvA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5vxv PEROXISOMAL MEMBRANE
PROTEIN PEX15
(Saccharomyces
cerevisiae) 		5 / 9 ILE A 135
VAL A 184
LEU A 187
ILE A 237
PHE A 170
 None
 1.33A 4r38C-5vxvA:
undetectable		 4r38C-5vxvA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 5vxv PEROXISOMAL MEMBRANE
PROTEIN PEX15
(Saccharomyces
cerevisiae) 		5 / 10 ALA A 240
SER A 244
THR A 225
GLY A 186
LEU A 187
 None
 1.24A 5m5cE-5vxvA:
undetectable		 5m5cE-5vxvA:
9.62