SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vym'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		3 / 3 ARG A  33
ARG A  37
ILE A   6
 None
 0.75A 1uobA-5vymA:
undetectable		 1uobA-5vymA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_B_FLPB2701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		6 / 12 LEU A 119
LEU A  77
TYR A 107
GLY A 109
ALA A 110
LEU A  69
 None
 1.49A 2aylB-5vymA:
undetectable		 2aylB-5vymA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_1
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		4 / 5 PRO A  50
ALA A  52
ASP A   3
ASP A  54
 None
 1.10A 2nyuB-5vymA:
undetectable		 2nyuB-5vymA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		3 / 3 TYR A  58
VAL A  49
THR A   4
 None
 0.88A 2ygnA-5vymA:
undetectable		 2ygnA-5vymA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		5 / 12 LEU A 119
TYR A 107
GLY A 109
ALA A 110
LEU A  69
 None
 1.11A 3n8xA-5vymA:
undetectable		 3n8xA-5vymA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		5 / 11 LEU A 119
TYR A 107
GLY A 109
ALA A 110
LEU A  69
 None
 0.92A 3n8yA-5vymA:
undetectable		 3n8yA-5vymA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		5 / 11 VAL A  89
LEU A 119
TYR A 107
GLY A 109
LEU A  69
 None
 1.06A 3n8yA-5vymA:
undetectable		 3n8yA-5vymA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		6 / 12 LEU A 119
LEU A  77
TYR A 107
GLY A 109
ALA A 110
LEU A  69
 None
 1.32A 3nt1A-5vymA:
undetectable		 3nt1A-5vymA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		6 / 12 LEU A 119
LEU A  77
TYR A 107
GLY A 109
ALA A 110
LEU A  69
 None
 1.31A 3nt1B-5vymA:
undetectable		 3nt1B-5vymA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RDX_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		4 / 7 THR A  74
ARG A 116
GLY A 109
GLY A  94
 None
 0.89A 4rdxA-5vymA:
undetectable		 4rdxA-5vymA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		5 / 12 LEU A 119
TYR A 107
GLY A 109
ALA A 110
LEU A  69
 None
 0.88A 4rrwA-5vymA:
undetectable		 4rrwA-5vymA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		5 / 12 VAL A  89
LEU A 119
TYR A 107
GLY A 109
LEU A  69
 None
 1.00A 4rrwA-5vymA:
undetectable		 4rrwA-5vymA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		5 / 12 LEU A 119
TYR A 107
GLY A 109
ALA A 110
LEU A  69
 None
 0.86A 4rrwB-5vymA:
undetectable		 4rrwB-5vymA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		5 / 12 VAL A  89
LEU A 119
TYR A 107
GLY A 109
LEU A  69
 None
 1.01A 4rrwB-5vymA:
undetectable		 4rrwB-5vymA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		5 / 12 LEU A 119
TYR A 107
GLY A 109
ALA A 110
LEU A  69
 None
 0.88A 4rrwC-5vymA:
undetectable		 4rrwC-5vymA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		5 / 12 LEU A 119
TYR A 107
GLY A 109
ALA A 110
LEU A  69
 None
 0.87A 4rrxA-5vymA:
undetectable		 4rrxA-5vymA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		5 / 12 LEU A 119
TYR A 107
GLY A 109
ALA A 110
LEU A  69
 None
 0.91A 4rrxB-5vymA:
undetectable		 4rrxB-5vymA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		5 / 12 LEU A 119
TYR A 107
GLY A 109
ALA A 110
LEU A  69
 None
 0.88A 4rrzA-5vymA:
undetectable		 4rrzA-5vymA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		5 / 12 VAL A  89
LEU A 119
TYR A 107
GLY A 109
LEU A  69
 None
 1.00A 4rrzA-5vymA:
undetectable		 4rrzA-5vymA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		5 / 12 LEU A 119
TYR A 107
GLY A 109
ALA A 110
LEU A  69
 None
 0.86A 4rrzB-5vymA:
undetectable		 4rrzB-5vymA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		5 / 12 VAL A  89
LEU A 119
TYR A 107
GLY A 109
LEU A  69
 None
 1.01A 4rrzB-5vymA:
undetectable		 4rrzB-5vymA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		5 / 12 LEU A 119
TYR A 107
GLY A 109
ALA A 110
LEU A  69
 None
 0.88A 4rrzC-5vymA:
undetectable		 4rrzC-5vymA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G44_A_YTZA1512_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		5 / 9 LEU A 217
LEU A 151
ALA A 223
ARG A 219
ALA A 150
 None
 1.20A 5g44A-5vymA:
undetectable		 5g44A-5vymA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		5 / 12 LEU A 119
TYR A 107
GLY A 109
ALA A 110
LEU A  69
 None
 1.13A 5ikrA-5vymA:
undetectable		 5ikrA-5vymA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		6 / 12 LEU A 119
LEU A  77
TYR A 107
GLY A 109
ALA A 110
LEU A  69
 None
 1.32A 5jvzA-5vymA:
undetectable		 5jvzA-5vymA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		5 / 12 LEU A 119
TYR A 107
GLY A 109
ALA A 110
LEU A  69
 None
 0.93A 5jvzB-5vymA:
undetectable		 5jvzB-5vymA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		5 / 12 LEU A 222
LEU A 217
ALA A 150
SER A 144
LEU A 142
 None
 1.22A 5mwyA-5vymA:
undetectable		 5mwyA-5vymA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 5vym BETA-GALACTOSIDASE
BGAB
(Bifidobacterium
adolescentis) 		5 / 12 VAL A 192
ALA A 191
GLY A 206
LEU A 209
LEU A 217
 None
 1.12A 6f6iA-5vymA:
1.5
6f6iB-5vymA:
undetectable		 6f6iA-5vymA:
16.24
6f6iB-5vymA:
21.91