SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vyo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1V_A_H4BA700_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
0.99A 1d1vA-5vyoA:
undetectable
1d1vB-5vyoA:
undetectable
1d1vA-5vyoA:
10.31
1d1vB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1V_B_H4BB701_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.02A 1d1vA-5vyoA:
undetectable
1d1vB-5vyoA:
undetectable
1d1vA-5vyoA:
10.31
1d1vB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1W_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.03A 1d1wA-5vyoA:
1.0
1d1wB-5vyoA:
undetectable
1d1wA-5vyoA:
10.31
1d1wB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1W_B_H4BB601_1
(NITRIC OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.00A 1d1wA-5vyoA:
1.0
1d1wB-5vyoA:
undetectable
1d1wA-5vyoA:
10.31
1d1wB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1X_A_H4BA600_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME DOMAIN)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.01A 1d1xA-5vyoA:
undetectable
1d1xB-5vyoA:
undetectable
1d1xA-5vyoA:
10.31
1d1xB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1X_B_H4BB601_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME DOMAIN)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.01A 1d1xA-5vyoA:
undetectable
1d1xB-5vyoA:
undetectable
1d1xA-5vyoA:
10.31
1d1xB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DM8_A_H4BA1600_1
(NITRIC OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.01A 1dm8A-5vyoA:
1.0
1dm8B-5vyoA:
undetectable
1dm8A-5vyoA:
10.31
1dm8B-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DM8_B_H4BB2600_1
(NITRIC OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.98A 1dm8A-5vyoA:
1.0
1dm8B-5vyoA:
undetectable
1dm8A-5vyoA:
10.31
1dm8B-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_A_BHSA1610_1
(NITRIC OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 8 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.02A 1dmiA-5vyoA:
undetectable
1dmiB-5vyoA:
undetectable
1dmiA-5vyoA:
10.31
1dmiB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_B_BHSB2610_1
(NITRIC OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.95A 1dmiA-5vyoA:
undetectable
1dmiB-5vyoA:
undetectable
1dmiA-5vyoA:
10.31
1dmiB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
5 / 7 ARG A  68
PHE A  39
THR A  97
VAL A 100
ALA A  46
None
1.24A 1fo4B-5vyoA:
undetectable
1fo4B-5vyoA:
4.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOP_B_H4BB2600_1
(NITRIC-OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.98A 1fopA-5vyoA:
undetectable
1fopB-5vyoA:
undetectable
1fopA-5vyoA:
10.31
1fopB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
5 / 12 ARG A  68
PHE A  39
THR A  97
VAL A 100
ALA A  46
None
1.23A 1n5xA-5vyoA:
undetectable
1n5xA-5vyoA:
4.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
5 / 12 ARG A  68
PHE A  39
THR A  97
VAL A 100
ALA A  46
None
1.23A 1n5xB-5vyoA:
undetectable
1n5xB-5vyoA:
4.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.00A 1nseA-5vyoA:
undetectable
1nseB-5vyoA:
undetectable
1nseA-5vyoA:
10.31
1nseB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
0.97A 1p6lA-5vyoA:
undetectable
1p6lB-5vyoA:
undetectable
1p6lA-5vyoA:
12.76
1p6lB-5vyoA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.99A 1p6lA-5vyoA:
undetectable
1p6lB-5vyoA:
undetectable
1p6lA-5vyoA:
12.76
1p6lB-5vyoA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
0.99A 1p6mA-5vyoA:
undetectable
1p6mB-5vyoA:
undetectable
1p6mA-5vyoA:
12.76
1p6mB-5vyoA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.02A 1p6mA-5vyoA:
undetectable
1p6mB-5vyoA:
undetectable
1p6mA-5vyoA:
12.76
1p6mB-5vyoA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.01A 1p6nA-5vyoA:
undetectable
1p6nB-5vyoA:
undetectable
1p6nA-5vyoA:
12.76
1p6nB-5vyoA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6N_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.00A 1p6nA-5vyoA:
undetectable
1p6nB-5vyoA:
undetectable
1p6nA-5vyoA:
12.76
1p6nB-5vyoA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q2O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.02A 1q2oA-5vyoA:
undetectable
1q2oB-5vyoA:
undetectable
1q2oA-5vyoA:
12.72
1q2oB-5vyoA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q2O_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.00A 1q2oA-5vyoA:
undetectable
1q2oB-5vyoA:
undetectable
1q2oA-5vyoA:
12.72
1q2oB-5vyoA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS8_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
0.99A 1rs8A-5vyoA:
undetectable
1rs8B-5vyoA:
undetectable
1rs8A-5vyoA:
12.72
1rs8B-5vyoA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS8_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.03A 1rs8A-5vyoA:
undetectable
1rs8B-5vyoA:
undetectable
1rs8A-5vyoA:
12.72
1rs8B-5vyoA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS9_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.02A 1rs9A-5vyoA:
undetectable
1rs9B-5vyoA:
undetectable
1rs9A-5vyoA:
12.72
1rs9B-5vyoA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS9_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.99A 1rs9A-5vyoA:
undetectable
1rs9B-5vyoA:
undetectable
1rs9A-5vyoA:
12.72
1rs9B-5vyoA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.06A 1zzrA-5vyoA:
undetectable
1zzrB-5vyoA:
undetectable
1zzrA-5vyoA:
11.83
1zzrB-5vyoA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.06A 1zzrA-5vyoA:
undetectable
1zzrB-5vyoA:
undetectable
1zzrA-5vyoA:
11.83
1zzrB-5vyoA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZS_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.02A 1zzsA-5vyoA:
undetectable
1zzsB-5vyoA:
undetectable
1zzsA-5vyoA:
12.72
1zzsB-5vyoA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZS_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.01A 1zzsA-5vyoA:
0.5
1zzsB-5vyoA:
undetectable
1zzsA-5vyoA:
12.72
1zzsB-5vyoA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.06A 1zzuA-5vyoA:
0.4
1zzuB-5vyoA:
undetectable
1zzuA-5vyoA:
11.83
1zzuB-5vyoA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX2_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.03A 2hx2A-5vyoA:
0.9
2hx2B-5vyoA:
undetectable
2hx2A-5vyoA:
12.72
2hx2B-5vyoA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX2_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.04A 2hx2A-5vyoA:
0.9
2hx2B-5vyoA:
undetectable
2hx2A-5vyoA:
12.72
2hx2B-5vyoA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.04A 2nseA-5vyoA:
undetectable
2nseB-5vyoA:
undetectable
2nseA-5vyoA:
10.31
2nseB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEO_A_LNRA200_1
(D7R4 PROTEIN)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
5 / 12 GLU A  37
ARG A  68
TYR A  41
PHE A 101
GLU A  50
None
1.31A 2qeoA-5vyoA:
undetectable
2qeoA-5vyoA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_B_SALB1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
5 / 9 ARG A  68
PHE A  39
THR A  97
VAL A 100
ALA A  46
None
1.26A 3ax7B-5vyoA:
undetectable
3ax7B-5vyoA:
4.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.00A 3dqsA-5vyoA:
undetectable
3dqsB-5vyoA:
undetectable
3dqsA-5vyoA:
12.72
3dqsB-5vyoA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.02A 3dqsA-5vyoA:
undetectable
3dqsB-5vyoA:
undetectable
3dqsA-5vyoA:
12.72
3dqsB-5vyoA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.02A 3dqtA-5vyoA:
undetectable
3dqtB-5vyoA:
undetectable
3dqtA-5vyoA:
12.72
3dqtB-5vyoA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.00A 3dqtA-5vyoA:
undetectable
3dqtB-5vyoA:
undetectable
3dqtA-5vyoA:
12.72
3dqtB-5vyoA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWX_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.02A 3jwxA-5vyoA:
0.9
3jwxB-5vyoA:
undetectable
3jwxA-5vyoA:
10.31
3jwxB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWX_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.04A 3jwxA-5vyoA:
0.9
3jwxB-5vyoA:
undetectable
3jwxA-5vyoA:
10.31
3jwxB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.05A 3jwyA-5vyoA:
1.0
3jwyB-5vyoA:
undetectable
3jwyA-5vyoA:
10.31
3jwyB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.08A 3jwyA-5vyoA:
1.0
3jwyB-5vyoA:
undetectable
3jwyA-5vyoA:
10.31
3jwyB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.03A 3jwzA-5vyoA:
undetectable
3jwzB-5vyoA:
undetectable
3jwzA-5vyoA:
10.31
3jwzB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.02A 3jwzA-5vyoA:
undetectable
3jwzB-5vyoA:
undetectable
3jwzA-5vyoA:
10.31
3jwzB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.05A 3jx3A-5vyoA:
0.4
3jx3B-5vyoA:
undetectable
3jx3A-5vyoA:
11.83
3jx3B-5vyoA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.09A 3jx5A-5vyoA:
undetectable
3jx5B-5vyoA:
0.4
3jx5A-5vyoA:
11.83
3jx5B-5vyoA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.06A 3jx6A-5vyoA:
0.4
3jx6B-5vyoA:
0.5
3jx6A-5vyoA:
12.50
3jx6B-5vyoA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
5 / 12 GLY A 166
GLN A 165
VAL A 189
LEU A 185
ILE A 156
None
1.33A 3mnpA-5vyoA:
undetectable
3mnpA-5vyoA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Q_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.06A 3n5qA-5vyoA:
undetectable
3n5qB-5vyoA:
undetectable
3n5qA-5vyoA:
10.31
3n5qB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5R_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.04A 3n5rA-5vyoA:
undetectable
3n5rB-5vyoA:
undetectable
3n5rA-5vyoA:
10.31
3n5rB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5R_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.98A 3n5rA-5vyoA:
undetectable
3n5rB-5vyoA:
undetectable
3n5rA-5vyoA:
10.31
3n5rB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5S_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.08A 3n5sA-5vyoA:
undetectable
3n5sB-5vyoA:
undetectable
3n5sA-5vyoA:
10.31
3n5sB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5S_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.05A 3n5sA-5vyoA:
undetectable
3n5sB-5vyoA:
undetectable
3n5sA-5vyoA:
10.31
3n5sB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.07A 3n5tA-5vyoA:
undetectable
3n5tB-5vyoA:
undetectable
3n5tA-5vyoA:
10.31
3n5tB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.00A 3n5tA-5vyoA:
undetectable
3n5tB-5vyoA:
undetectable
3n5tA-5vyoA:
10.31
3n5tB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.03A 3n6eA-5vyoA:
undetectable
3n6eB-5vyoA:
0.8
3n6eA-5vyoA:
10.31
3n6eB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.02A 3n6eA-5vyoA:
undetectable
3n6eB-5vyoA:
0.8
3n6eA-5vyoA:
10.31
3n6eB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6F_A_H4BA600_1
('NITRIC OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.05A 3n6fA-5vyoA:
undetectable
3n6fB-5vyoA:
undetectable
3n6fA-5vyoA:
10.31
3n6fB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6F_B_H4BB600_1
('NITRIC OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.05A 3n6fA-5vyoA:
undetectable
3n6fB-5vyoA:
0.6
3n6fA-5vyoA:
10.31
3n6fB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6G_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.04A 3n6gA-5vyoA:
0.5
3n6gB-5vyoA:
undetectable
3n6gA-5vyoA:
10.31
3n6gB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6G_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.05A 3n6gA-5vyoA:
0.5
3n6gB-5vyoA:
undetectable
3n6gA-5vyoA:
10.31
3n6gB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLD_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.06A 3nldA-5vyoA:
0.4
3nldB-5vyoA:
0.5
3nldA-5vyoA:
10.31
3nldB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.02A 3nleA-5vyoA:
undetectable
3nleB-5vyoA:
undetectable
3nleA-5vyoA:
10.31
3nleB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.99A 3nleA-5vyoA:
undetectable
3nleB-5vyoA:
undetectable
3nleA-5vyoA:
10.31
3nleB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLF_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.06A 3nlfA-5vyoA:
0.8
3nlfB-5vyoA:
undetectable
3nlfA-5vyoA:
10.31
3nlfB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLG_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.03A 3nlgA-5vyoA:
1.0
3nlgB-5vyoA:
undetectable
3nlgA-5vyoA:
10.31
3nlgB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLG_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.01A 3nlgA-5vyoA:
1.0
3nlgB-5vyoA:
undetectable
3nlgA-5vyoA:
10.31
3nlgB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLH_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.05A 3nlhA-5vyoA:
undetectable
3nlhB-5vyoA:
0.6
3nlhA-5vyoA:
10.31
3nlhB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLH_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.07A 3nlhA-5vyoA:
undetectable
3nlhB-5vyoA:
0.6
3nlhA-5vyoA:
10.31
3nlhB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLI_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.02A 3nliA-5vyoA:
undetectable
3nliB-5vyoA:
undetectable
3nliA-5vyoA:
10.31
3nliB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLI_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.04A 3nliA-5vyoA:
undetectable
3nliB-5vyoA:
undetectable
3nliA-5vyoA:
10.31
3nliB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.09A 3nljA-5vyoA:
0.4
3nljB-5vyoA:
undetectable
3nljA-5vyoA:
12.50
3nljB-5vyoA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 8 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.05A 3nlqA-5vyoA:
undetectable
3nlqB-5vyoA:
undetectable
3nlqA-5vyoA:
11.83
3nlqB-5vyoA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.09A 3nlqA-5vyoA:
undetectable
3nlqB-5vyoA:
undetectable
3nlqA-5vyoA:
11.83
3nlqB-5vyoA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLU_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.05A 3nluA-5vyoA:
undetectable
3nluB-5vyoA:
0.4
3nluA-5vyoA:
10.31
3nluB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NOS_A_H4BA511_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
0.97A 3nosA-5vyoA:
undetectable
3nosB-5vyoA:
undetectable
3nosA-5vyoA:
12.32
3nosB-5vyoA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NOS_B_H4BB1011_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.95A 3nosA-5vyoA:
undetectable
3nosB-5vyoA:
undetectable
3nosA-5vyoA:
12.32
3nosB-5vyoA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNH_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.03A 3pnhA-5vyoA:
undetectable
3pnhB-5vyoA:
undetectable
3pnhA-5vyoA:
12.72
3pnhB-5vyoA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNH_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.03A 3pnhA-5vyoA:
undetectable
3pnhB-5vyoA:
undetectable
3pnhA-5vyoA:
12.72
3pnhB-5vyoA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQO_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.03A 3rqoA-5vyoA:
undetectable
3rqoB-5vyoA:
undetectable
3rqoA-5vyoA:
9.71
3rqoB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQO_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.00A 3rqoA-5vyoA:
undetectable
3rqoB-5vyoA:
undetectable
3rqoA-5vyoA:
9.71
3rqoB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQP_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.04A 3rqpA-5vyoA:
undetectable
3rqpB-5vyoA:
0.6
3rqpA-5vyoA:
9.71
3rqpB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C3A_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.04A 4c3aA-5vyoA:
undetectable
4c3aB-5vyoA:
undetectable
4c3aA-5vyoA:
9.71
4c3aB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C3A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.03A 4c3aA-5vyoA:
undetectable
4c3aB-5vyoA:
undetectable
4c3aA-5vyoA:
9.71
4c3aB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAR_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.04A 4carA-5vyoA:
undetectable
4carB-5vyoA:
undetectable
4carA-5vyoA:
9.71
4carB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAR_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.04A 4carA-5vyoA:
undetectable
4carB-5vyoA:
undetectable
4carA-5vyoA:
9.71
4carB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CFT_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
0.98A 4cftA-5vyoA:
undetectable
4cftB-5vyoA:
0.4
4cftA-5vyoA:
9.71
4cftB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CFT_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.99A 4cftA-5vyoA:
undetectable
4cftB-5vyoA:
0.4
4cftA-5vyoA:
9.71
4cftB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.01A 4ctyA-5vyoA:
undetectable
4ctyB-5vyoA:
0.4
4ctyA-5vyoA:
9.71
4ctyB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.04A 4ctyA-5vyoA:
undetectable
4ctyB-5vyoA:
0.4
4ctyA-5vyoA:
9.71
4ctyB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.09A 4ctzA-5vyoA:
undetectable
4ctzB-5vyoA:
undetectable
4ctzA-5vyoA:
9.71
4ctzB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.05A 4ctzA-5vyoA:
undetectable
4ctzB-5vyoA:
undetectable
4ctzA-5vyoA:
9.71
4ctzB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU0_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.03A 4cu0A-5vyoA:
undetectable
4cu0B-5vyoA:
undetectable
4cu0A-5vyoA:
9.71
4cu0B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU0_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.98A 4cu0A-5vyoA:
undetectable
4cu0B-5vyoA:
undetectable
4cu0A-5vyoA:
9.71
4cu0B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU1_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.02A 4cu1A-5vyoA:
undetectable
4cu1B-5vyoA:
undetectable
4cu1A-5vyoA:
9.71
4cu1B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWV_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.00A 4cwvA-5vyoA:
undetectable
4cwvB-5vyoA:
undetectable
4cwvA-5vyoA:
9.71
4cwvB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWV_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.96A 4cwvA-5vyoA:
undetectable
4cwvB-5vyoA:
undetectable
4cwvA-5vyoA:
9.71
4cwvB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWW_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.02A 4cwwA-5vyoA:
0.5
4cwwB-5vyoA:
undetectable
4cwwA-5vyoA:
9.71
4cwwB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWW_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.03A 4cwwA-5vyoA:
0.5
4cwwB-5vyoA:
undetectable
4cwwA-5vyoA:
9.71
4cwwB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWX_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.04A 4cwxA-5vyoA:
undetectable
4cwxB-5vyoA:
undetectable
4cwxA-5vyoA:
9.71
4cwxB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWX_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.03A 4cwxA-5vyoA:
undetectable
4cwxB-5vyoA:
undetectable
4cwxA-5vyoA:
9.71
4cwxB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.05A 4cwyA-5vyoA:
undetectable
4cwyB-5vyoA:
undetectable
4cwyA-5vyoA:
9.71
4cwyB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.02A 4cwyA-5vyoA:
undetectable
4cwyB-5vyoA:
undetectable
4cwyA-5vyoA:
9.71
4cwyB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.02A 4cwzA-5vyoA:
undetectable
4cwzB-5vyoA:
undetectable
4cwzA-5vyoA:
9.71
4cwzB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.98A 4cwzA-5vyoA:
undetectable
4cwzB-5vyoA:
undetectable
4cwzA-5vyoA:
9.71
4cwzB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX0_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.03A 4cx0A-5vyoA:
undetectable
4cx0B-5vyoA:
0.4
4cx0A-5vyoA:
9.71
4cx0B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX0_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.01A 4cx0A-5vyoA:
undetectable
4cx0B-5vyoA:
0.4
4cx0A-5vyoA:
9.71
4cx0B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.07A 4cx3A-5vyoA:
0.5
4cx3B-5vyoA:
undetectable
4cx3A-5vyoA:
11.83
4cx3B-5vyoA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.07A 4cx4A-5vyoA:
0.4
4cx4B-5vyoA:
undetectable
4cx4A-5vyoA:
11.83
4cx4B-5vyoA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1O_A_H4BA1481_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
0.99A 4d1oA-5vyoA:
undetectable
4d1oB-5vyoA:
undetectable
4d1oA-5vyoA:
12.05
4d1oB-5vyoA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1O_B_H4BB1481_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.00A 4d1oA-5vyoA:
undetectable
4d1oB-5vyoA:
undetectable
4d1oA-5vyoA:
12.05
4d1oB-5vyoA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1P_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.00A 4d1pA-5vyoA:
undetectable
4d1pB-5vyoA:
undetectable
4d1pA-5vyoA:
12.05
4d1pB-5vyoA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.00A 4d33A-5vyoA:
undetectable
4d33B-5vyoA:
undetectable
4d33A-5vyoA:
9.71
4d33B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D34_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
0.97A 4d34A-5vyoA:
0.9
4d34B-5vyoA:
0.8
4d34A-5vyoA:
9.71
4d34B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D34_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.94A 4d34A-5vyoA:
0.9
4d34B-5vyoA:
0.8
4d34A-5vyoA:
9.71
4d34B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D35_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.96A 4d35A-5vyoA:
undetectable
4d35B-5vyoA:
0.5
4d35A-5vyoA:
9.71
4d35B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D36_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.00A 4d36A-5vyoA:
undetectable
4d36B-5vyoA:
undetectable
4d36A-5vyoA:
9.71
4d36B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D36_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.01A 4d36A-5vyoA:
undetectable
4d36B-5vyoA:
undetectable
4d36A-5vyoA:
9.71
4d36B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D37_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
0.99A 4d37A-5vyoA:
undetectable
4d37B-5vyoA:
0.9
4d37A-5vyoA:
9.71
4d37B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D37_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.99A 4d37A-5vyoA:
undetectable
4d37B-5vyoA:
0.9
4d37A-5vyoA:
9.71
4d37B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D38_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
0.99A 4d38A-5vyoA:
1.1
4d38B-5vyoA:
undetectable
4d38A-5vyoA:
9.71
4d38B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D38_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.99A 4d38A-5vyoA:
1.1
4d38B-5vyoA:
undetectable
4d38A-5vyoA:
9.71
4d38B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.04A 4d39A-5vyoA:
undetectable
4d39B-5vyoA:
undetectable
4d39A-5vyoA:
9.71
4d39B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3A_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
0.98A 4d3aA-5vyoA:
undetectable
4d3aB-5vyoA:
undetectable
4d3aA-5vyoA:
9.71
4d3aB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.01A 4d3aA-5vyoA:
undetectable
4d3aB-5vyoA:
undetectable
4d3aA-5vyoA:
9.71
4d3aB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMX_A_H4BA502_1
(SUBUNIT A)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.03A 4imxA-5vyoA:
undetectable
4imxB-5vyoA:
undetectable
4imxA-5vyoA:
9.95
4imxB-5vyoA:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMX_B_H4BB502_1
(SUBUNIT A)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.06A 4imxA-5vyoA:
undetectable
4imxB-5vyoA:
undetectable
4imxA-5vyoA:
9.95
4imxB-5vyoA:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSK_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.04A 4jskA-5vyoA:
0.5
4jskB-5vyoA:
undetectable
4jskA-5vyoA:
9.71
4jskB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSL_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.06A 4jslA-5vyoA:
undetectable
4jslB-5vyoA:
0.4
4jslA-5vyoA:
9.71
4jslB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSL_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.07A 4jslA-5vyoA:
undetectable
4jslB-5vyoA:
0.4
4jslA-5vyoA:
9.71
4jslB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSM_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.01A 4jsmA-5vyoA:
undetectable
4jsmB-5vyoA:
undetectable
4jsmA-5vyoA:
9.71
4jsmB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSM_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.00A 4jsmA-5vyoA:
undetectable
4jsmB-5vyoA:
undetectable
4jsmA-5vyoA:
9.71
4jsmB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5H_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.04A 4k5hA-5vyoA:
undetectable
4k5hB-5vyoA:
undetectable
4k5hA-5vyoA:
9.71
4k5hB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5H_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.01A 4k5hA-5vyoA:
undetectable
4k5hB-5vyoA:
undetectable
4k5hA-5vyoA:
9.71
4k5hB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5I_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.04A 4k5iA-5vyoA:
undetectable
4k5iB-5vyoA:
undetectable
4k5iA-5vyoA:
9.71
4k5iB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5I_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.00A 4k5iA-5vyoA:
undetectable
4k5iB-5vyoA:
undetectable
4k5iA-5vyoA:
9.71
4k5iB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.04A 4k5jA-5vyoA:
0.5
4k5jB-5vyoA:
undetectable
4k5jA-5vyoA:
9.71
4k5jB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.01A 4k5jA-5vyoA:
undetectable
4k5jB-5vyoA:
undetectable
4k5jA-5vyoA:
9.71
4k5jB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5K_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.05A 4k5kA-5vyoA:
undetectable
4k5kB-5vyoA:
undetectable
4k5kA-5vyoA:
9.71
4k5kB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCP_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.05A 4kcpA-5vyoA:
undetectable
4kcpB-5vyoA:
undetectable
4kcpA-5vyoA:
9.71
4kcpB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCP_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.01A 4kcpA-5vyoA:
undetectable
4kcpB-5vyoA:
undetectable
4kcpA-5vyoA:
9.71
4kcpB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCQ_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.04A 4kcqA-5vyoA:
undetectable
4kcqB-5vyoA:
undetectable
4kcqA-5vyoA:
9.71
4kcqB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCR_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.03A 4kcrA-5vyoA:
undetectable
4kcrB-5vyoA:
undetectable
4kcrA-5vyoA:
9.71
4kcrB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCR_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.02A 4kcrA-5vyoA:
undetectable
4kcrB-5vyoA:
undetectable
4kcrA-5vyoA:
9.71
4kcrB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCS_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.03A 4kcsA-5vyoA:
undetectable
4kcsB-5vyoA:
undetectable
4kcsA-5vyoA:
9.71
4kcsB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCS_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.00A 4kcsA-5vyoA:
undetectable
4kcsB-5vyoA:
undetectable
4kcsA-5vyoA:
9.71
4kcsB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUW_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.02A 4luwA-5vyoA:
undetectable
4luwB-5vyoA:
undetectable
4luwA-5vyoA:
9.95
4luwB-5vyoA:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUW_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.07A 4luwA-5vyoA:
undetectable
4luwB-5vyoA:
undetectable
4luwA-5vyoA:
9.95
4luwB-5vyoA:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.04A 4uh7A-5vyoA:
0.5
4uh7B-5vyoA:
undetectable
4uh7A-5vyoA:
9.71
4uh7B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.04A 4uh7A-5vyoA:
0.5
4uh7B-5vyoA:
undetectable
4uh7A-5vyoA:
9.71
4uh7B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH8_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.03A 4uh8A-5vyoA:
undetectable
4uh8B-5vyoA:
undetectable
4uh8A-5vyoA:
9.71
4uh8B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH8_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.00A 4uh8A-5vyoA:
undetectable
4uh8B-5vyoA:
undetectable
4uh8A-5vyoA:
9.71
4uh8B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH9_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.01A 4uh9A-5vyoA:
undetectable
4uh9B-5vyoA:
0.9
4uh9A-5vyoA:
9.71
4uh9B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH9_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.99A 4uh9A-5vyoA:
undetectable
4uh9B-5vyoA:
0.9
4uh9A-5vyoA:
9.71
4uh9B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHA_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.04A 4uhaA-5vyoA:
undetectable
4uhaB-5vyoA:
undetectable
4uhaA-5vyoA:
9.71
4uhaB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHA_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.02A 4uhaA-5vyoA:
undetectable
4uhaB-5vyoA:
undetectable
4uhaA-5vyoA:
9.71
4uhaB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPQ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.05A 4upqA-5vyoA:
undetectable
4upqB-5vyoA:
undetectable
4upqA-5vyoA:
9.71
4upqB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPQ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.05A 4upqA-5vyoA:
undetectable
4upqB-5vyoA:
undetectable
4upqA-5vyoA:
9.71
4upqB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPR_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.07A 4uprA-5vyoA:
undetectable
4uprB-5vyoA:
undetectable
4uprA-5vyoA:
9.71
4uprB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPR_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.02A 4uprA-5vyoA:
undetectable
4uprB-5vyoA:
undetectable
4uprA-5vyoA:
9.71
4uprB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPS_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.05A 4upsA-5vyoA:
undetectable
4upsB-5vyoA:
undetectable
4upsA-5vyoA:
9.71
4upsB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPS_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.04A 4upsA-5vyoA:
undetectable
4upsB-5vyoA:
undetectable
4upsA-5vyoA:
9.71
4upsB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPT_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.07A 4uptA-5vyoA:
undetectable
4uptB-5vyoA:
0.9
4uptA-5vyoA:
9.71
4uptB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPT_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.02A 4uptA-5vyoA:
undetectable
4uptB-5vyoA:
0.9
4uptA-5vyoA:
9.71
4uptB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADJ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.00A 5adjA-5vyoA:
undetectable
5adjB-5vyoA:
undetectable
5adjA-5vyoA:
9.71
5adjB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADJ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.99A 5adjA-5vyoA:
undetectable
5adjB-5vyoA:
undetectable
5adjA-5vyoA:
9.71
5adjB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADK_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
0.98A 5adkA-5vyoA:
0.9
5adkB-5vyoA:
undetectable
5adkA-5vyoA:
9.71
5adkB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADK_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.99A 5adkA-5vyoA:
0.9
5adkB-5vyoA:
undetectable
5adkA-5vyoA:
9.71
5adkB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
0.95A 5adlA-5vyoA:
undetectable
5adlB-5vyoA:
undetectable
5adlA-5vyoA:
9.71
5adlB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.01A 5adlA-5vyoA:
undetectable
5adlB-5vyoA:
undetectable
5adlA-5vyoA:
9.71
5adlB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
0.99A 5admA-5vyoA:
undetectable
5admB-5vyoA:
undetectable
5admA-5vyoA:
9.71
5admB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.00A 5admA-5vyoA:
undetectable
5admB-5vyoA:
undetectable
5admA-5vyoA:
9.71
5admB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADN_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
0.98A 5adnA-5vyoA:
0.5
5adnB-5vyoA:
undetectable
5adnA-5vyoA:
9.71
5adnB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADN_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.01A 5adnA-5vyoA:
0.5
5adnB-5vyoA:
undetectable
5adnA-5vyoA:
9.71
5adnB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ2_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.03A 5fj2A-5vyoA:
0.9
5fj2B-5vyoA:
undetectable
5fj2A-5vyoA:
9.71
5fj2B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ2_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.01A 5fj2A-5vyoA:
0.9
5fj2B-5vyoA:
undetectable
5fj2A-5vyoA:
9.71
5fj2B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.03A 5fj3A-5vyoA:
undetectable
5fj3B-5vyoA:
undetectable
5fj3A-5vyoA:
9.71
5fj3B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.04A 5fj3A-5vyoA:
undetectable
5fj3B-5vyoA:
undetectable
5fj3A-5vyoA:
9.71
5fj3B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.01A 5fvyA-5vyoA:
undetectable
5fvyB-5vyoA:
undetectable
5fvyA-5vyoA:
9.71
5fvyB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.98A 5fvyA-5vyoA:
undetectable
5fvyB-5vyoA:
undetectable
5fvyA-5vyoA:
9.71
5fvyB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVZ_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.00A 5fvzA-5vyoA:
undetectable
5fvzB-5vyoA:
undetectable
5fvzA-5vyoA:
9.71
5fvzB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVZ_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.05A 5fvzA-5vyoA:
undetectable
5fvzB-5vyoA:
undetectable
5fvzA-5vyoA:
9.71
5fvzB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA901_0
(PROTEIN ARGONAUTE-2)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 5 LEU A  87
TYR A  85
LEU A  83
TYR A  41
None
1.34A 5ki6A-5vyoA:
undetectable
5ki6A-5vyoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.01A 5uo8A-5vyoA:
0.0
5uo8B-5vyoA:
undetectable
5uo8A-5vyoA:
12.05
5uo8B-5vyoA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.06A 5uo8C-5vyoA:
undetectable
5uo8D-5vyoA:
undetectable
5uo8C-5vyoA:
12.05
5uo8D-5vyoA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.02A 5uo9A-5vyoA:
0.0
5uo9B-5vyoA:
0.0
5uo9A-5vyoA:
12.05
5uo9B-5vyoA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.98A 5uo9A-5vyoA:
0.0
5uo9B-5vyoA:
undetectable
5uo9A-5vyoA:
12.05
5uo9B-5vyoA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.05A 5uo9C-5vyoA:
undetectable
5uo9D-5vyoA:
0.0
5uo9C-5vyoA:
12.05
5uo9D-5vyoA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.07A 5uo9C-5vyoA:
undetectable
5uo9D-5vyoA:
undetectable
5uo9C-5vyoA:
12.05
5uo9D-5vyoA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOD_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.05A 5uodA-5vyoA:
undetectable
5uodB-5vyoA:
undetectable
5uodA-5vyoA:
9.71
5uodB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV6_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.02A 5vv6A-5vyoA:
undetectable
5vv6B-5vyoA:
undetectable
5vv6A-5vyoA:
9.71
5vv6B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV6_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.04A 5vv6A-5vyoA:
undetectable
5vv6B-5vyoA:
undetectable
5vv6A-5vyoA:
9.71
5vv6B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.03A 5vv7A-5vyoA:
1.0
5vv7B-5vyoA:
0.5
5vv7A-5vyoA:
9.71
5vv7B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.04A 5vv7A-5vyoA:
undetectable
5vv7B-5vyoA:
undetectable
5vv7A-5vyoA:
9.71
5vv7B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV8_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.02A 5vv8A-5vyoA:
undetectable
5vv8B-5vyoA:
undetectable
5vv8A-5vyoA:
9.71
5vv8B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV9_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.03A 5vv9A-5vyoA:
undetectable
5vv9B-5vyoA:
undetectable
5vv9A-5vyoA:
9.71
5vv9B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV9_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.97A 5vv9A-5vyoA:
undetectable
5vv9B-5vyoA:
undetectable
5vv9A-5vyoA:
9.71
5vv9B-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVA_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
0.97A 5vvaA-5vyoA:
undetectable
5vvaB-5vyoA:
undetectable
5vvaA-5vyoA:
9.71
5vvaB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVA_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.00A 5vvaA-5vyoA:
undetectable
5vvaB-5vyoA:
undetectable
5vvaA-5vyoA:
9.71
5vvaB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.02A 5vvbA-5vyoA:
undetectable
5vvbB-5vyoA:
undetectable
5vvbA-5vyoA:
12.05
5vvbB-5vyoA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.00A 5vvbC-5vyoA:
undetectable
5vvbD-5vyoA:
0.0
5vvbC-5vyoA:
12.05
5vvbD-5vyoA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.02A 5vvcA-5vyoA:
0.0
5vvcB-5vyoA:
undetectable
5vvcA-5vyoA:
12.05
5vvcB-5vyoA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.05A 5vvcC-5vyoA:
undetectable
5vvcD-5vyoA:
undetectable
5vvcC-5vyoA:
12.05
5vvcD-5vyoA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.06A 5vvcC-5vyoA:
undetectable
5vvcD-5vyoA:
undetectable
5vvcC-5vyoA:
12.05
5vvcD-5vyoA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.98A 5vvdA-5vyoA:
0.4
5vvdB-5vyoA:
undetectable
5vvdA-5vyoA:
12.05
5vvdB-5vyoA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.02A 5vvdC-5vyoA:
undetectable
5vvdD-5vyoA:
undetectable
5vvdC-5vyoA:
12.05
5vvdD-5vyoA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVG_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
0.99A 5vvgA-5vyoA:
undetectable
5vvgB-5vyoA:
undetectable
5vvgA-5vyoA:
9.71
5vvgB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVG_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.00A 5vvgA-5vyoA:
undetectable
5vvgB-5vyoA:
undetectable
5vvgA-5vyoA:
9.71
5vvgB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.00A 5vvnA-5vyoA:
undetectable
5vvnB-5vyoA:
undetectable
5vvnA-5vyoA:
9.71
5vvnB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.05A 5vvnA-5vyoA:
undetectable
5vvnB-5vyoA:
undetectable
5vvnA-5vyoA:
9.71
5vvnB-5vyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
0.97A 6av6A-5vyoA:
0.0
6av6B-5vyoA:
undetectable
6av6A-5vyoA:
22.22
6av6B-5vyoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB503_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.98A 6av6A-5vyoA:
0.0
6av6B-5vyoA:
undetectable
6av6A-5vyoA:
22.22
6av6B-5vyoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.01A 6av6C-5vyoA:
undetectable
6av6D-5vyoA:
undetectable
6av6C-5vyoA:
22.22
6av6D-5vyoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.03A 6av6C-5vyoA:
undetectable
6av6D-5vyoA:
undetectable
6av6C-5vyoA:
22.22
6av6D-5vyoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.02A 6av7A-5vyoA:
undetectable
6av7B-5vyoA:
undetectable
6av7A-5vyoA:
22.22
6av7B-5vyoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.01A 6av7A-5vyoA:
0.0
6av7B-5vyoA:
0.0
6av7A-5vyoA:
22.22
6av7B-5vyoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.02A 6av7C-5vyoA:
0.0
6av7D-5vyoA:
0.0
6av7C-5vyoA:
22.22
6av7D-5vyoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.05A 6av7C-5vyoA:
0.0
6av7D-5vyoA:
0.0
6av7C-5vyoA:
22.22
6av7D-5vyoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWT_D_BEZD202_0
(PR 10 PROTEIN)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
3 / 3 PHE A 187
ASP A 186
LYS A 190
None
0.79A 6awtD-5vyoA:
undetectable
6awtD-5vyoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_A_H4BA502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.02A 6cieA-5vyoA:
undetectable
6cieB-5vyoA:
0.0
6cieA-5vyoA:
22.22
6cieB-5vyoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_B_H4BB502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 7 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.00A 6cieA-5vyoA:
undetectable
6cieB-5vyoA:
undetectable
6cieA-5vyoA:
22.22
6cieB-5vyoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_C_H4BC502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.03A 6cieC-5vyoA:
undetectable
6cieD-5vyoA:
undetectable
6cieC-5vyoA:
22.22
6cieD-5vyoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_D_H4BD502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.02A 6cieC-5vyoA:
0.0
6cieD-5vyoA:
undetectable
6cieC-5vyoA:
22.22
6cieD-5vyoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIF_B_H4BB502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
1.05A 6cifA-5vyoA:
0.0
6cifB-5vyoA:
undetectable
6cifA-5vyoA:
22.22
6cifB-5vyoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
8NSE_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.01A 8nseA-5vyoA:
undetectable
8nseB-5vyoA:
undetectable
8nseA-5vyoA:
10.31
8nseB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
8NSE_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.97A 8nseA-5vyoA:
undetectable
8nseB-5vyoA:
undetectable
8nseA-5vyoA:
10.31
8nseB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
9NSE_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 VAL A  57
TRP A  56
PHE A  49
GLU A  54
None
1.02A 9nseA-5vyoA:
undetectable
9nseB-5vyoA:
undetectable
9nseA-5vyoA:
10.31
9nseB-5vyoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
9NSE_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
5vyo THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Burkholderia
pseudomallei)
4 / 6 PHE A  49
GLU A  54
VAL A  57
TRP A  56
None
0.98A 9nseA-5vyoA:
undetectable
9nseB-5vyoA:
undetectable
9nseA-5vyoA:
10.31
9nseB-5vyoA:
10.31