SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5w0a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 THR A   5
PRO A   8
THR A   7
 THR  A   5 ( 0.8A)
PRO  A   8 ( 1.1A)
THR  A   7 ( 0.8A)
 0.83A 1a7yB-5w0aA:
undetectable		 1a7yB-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 THR A   5
PRO A   8
THR A   7
 THR  A   5 ( 0.8A)
PRO  A   8 ( 1.1A)
THR  A   7 ( 0.8A)
 0.73A 1dscC-5w0aA:
undetectable		 1dscC-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 THR A   7
THR A   5
PRO A   8
 THR  A   7 ( 0.8A)
THR  A   5 ( 0.8A)
PRO  A   8 ( 1.1A)
 0.74A 1dscC-5w0aA:
undetectable		 1dscC-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY4_A_SNPA437_1
(EXOGLUCANASE 1)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		8 / 12 ALA A 144
TYR A 146
TYR A 170
ASP A 172
GLN A 174
GLU A 196
ASP A 198
GLU A 201
 ALA  A 144 ( 0.0A)
TYR  A 146 ( 1.3A)
TYR  A 170 ( 1.3A)
ASP  A 172 ( 0.5A)
GLN  A 174 ( 0.5A)
GLU  A 196 ( 0.6A)
ASP  A 198 (-0.6A)
GLU  A 201 (-0.5A)
 0.36A 1dy4A-5w0aA:
48.5		 1dy4A-5w0aA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY4_A_SNPA437_1
(EXOGLUCANASE 1)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		6 / 12 ALA A 144
TYR A 146
TYR A 170
ASP A 198
GLU A 201
ASP A 322
 ALA  A 144 ( 0.0A)
TYR  A 146 ( 1.3A)
TYR  A 170 ( 1.3A)
ASP  A 198 (-0.6A)
GLU  A 201 (-0.5A)
ASP  A 322 ( 0.6A)
 0.76A 1dy4A-5w0aA:
48.5		 1dy4A-5w0aA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 THR A   7
THR A   5
PRO A   8
 THR  A   7 ( 0.8A)
THR  A   5 ( 0.8A)
PRO  A   8 ( 1.1A)
 0.78A 1fjaC-5w0aA:
undetectable		 1fjaC-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 THR A   7
THR A   5
PRO A   8
 THR  A   7 ( 0.8A)
THR  A   5 ( 0.8A)
PRO  A   8 ( 1.1A)
 0.77A 1fjaD-5w0aA:
undetectable		 1fjaD-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 THR A   5
PRO A   8
THR A   7
 THR  A   5 ( 0.8A)
PRO  A   8 ( 1.1A)
THR  A   7 ( 0.8A)
 0.88A 1i3wE-5w0aA:
undetectable		 1i3wE-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 THR A   7
THR A   5
PRO A   8
 THR  A   7 ( 0.8A)
THR  A   5 ( 0.8A)
PRO  A   8 ( 1.1A)
 0.87A 1i3wE-5w0aA:
undetectable		 1i3wE-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 THR A   7
THR A   5
PRO A   8
 THR  A   7 ( 0.8A)
THR  A   5 ( 0.8A)
PRO  A   8 ( 1.1A)
 0.83A 1i3wG-5w0aA:
undetectable		 1i3wG-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 THR A   7
THR A   5
PRO A   8
 THR  A   7 ( 0.8A)
THR  A   5 ( 0.8A)
PRO  A   8 ( 1.1A)
 0.83A 1i3wH-5w0aA:
undetectable		 1i3wH-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 THR A   5
PRO A   8
THR A   7
 THR  A   5 ( 0.8A)
PRO  A   8 ( 1.1A)
THR  A   7 ( 0.8A)
 0.84A 1mnvD-5w0aA:
undetectable		 1mnvD-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 THR A   5
PRO A   8
THR A   7
 THR  A   5 ( 0.8A)
PRO  A   8 ( 1.1A)
THR  A   7 ( 0.8A)
 0.82A 1ovfB-5w0aA:
undetectable		 1ovfB-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 THR A   5
PRO A   8
THR A   7
 THR  A   5 ( 0.8A)
PRO  A   8 ( 1.1A)
THR  A   7 ( 0.8A)
 0.85A 1unjL-5w0aA:
undetectable		 1unjL-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 THR A   7
THR A   5
PRO A   8
 THR  A   7 ( 0.8A)
THR  A   5 ( 0.8A)
PRO  A   8 ( 1.1A)
 0.83A 1unjL-5w0aA:
undetectable		 1unjL-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 THR A   5
PRO A   8
THR A   7
 THR  A   5 ( 0.8A)
PRO  A   8 ( 1.1A)
THR  A   7 ( 0.8A)
 0.85A 1unjR-5w0aA:
undetectable		 1unjR-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 THR A   7
THR A   5
PRO A   8
 THR  A   7 ( 0.8A)
THR  A   5 ( 0.8A)
PRO  A   8 ( 1.1A)
 0.79A 1unjW-5w0aA:
undetectable		 1unjW-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 THR A   5
PRO A   8
THR A   7
 THR  A   5 ( 0.8A)
PRO  A   8 ( 1.1A)
THR  A   7 ( 0.8A)
 0.86A 1unjX-5w0aA:
undetectable		 1unjX-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 THR A   5
PRO A   8
THR A   7
 THR  A   5 ( 0.8A)
PRO  A   8 ( 1.1A)
THR  A   7 ( 0.8A)
 0.84A 1unmE-5w0aA:
undetectable		 1unmE-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 THR A   7
THR A   5
PRO A   8
 THR  A   7 ( 0.8A)
THR  A   5 ( 0.8A)
PRO  A   8 ( 1.1A)
 0.80A 1unmE-5w0aA:
undetectable		 1unmE-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 THR A   5
PRO A   8
THR A   7
 THR  A   5 ( 0.8A)
PRO  A   8 ( 1.1A)
THR  A   7 ( 0.8A)
 0.83A 1unmF-5w0aA:
undetectable		 1unmF-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 THR A   7
THR A   5
PRO A   8
 THR  A   7 ( 0.8A)
THR  A   5 ( 0.8A)
PRO  A   8 ( 1.1A)
 0.85A 1unmF-5w0aA:
undetectable		 1unmF-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		4 / 6 PHE A 359
VAL A 357
LEU A 137
PHE A 130
 PHE  A 359 ( 1.3A)
VAL  A 357 ( 0.6A)
LEU  A 137 ( 0.6A)
PHE  A 130 ( 1.3A)
 1.00A 1wrlB-5w0aA:
undetectable		 1wrlB-5w0aA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 GLY A 140
GLU A 141
ASN A 326
 GLY  A 140 ( 0.0A)
GLU  A 141 ( 0.6A)
ASN  A 326 ( 0.6A)
 0.72A 1zq9A-5w0aA:
undetectable		 1zq9A-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 THR A   7
THR A   5
PRO A   8
 THR  A   7 ( 0.8A)
THR  A   5 ( 0.8A)
PRO  A   8 ( 1.1A)
 0.87A 209dC-5w0aA:
undetectable		 209dC-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		4 / 8 TYR A  38
ASP A  35
TYR A 170
TYR A 146
 TYR  A  38 ( 1.3A)
ASP  A  35 ( 0.6A)
TYR  A 170 ( 1.3A)
TYR  A 146 ( 1.3A)
 1.37A 2bteA-5w0aA:
undetectable		 2bteA-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		4 / 8 TYR A  38
ASP A  35
TYR A 170
TYR A 146
 TYR  A  38 ( 1.3A)
ASP  A  35 ( 0.6A)
TYR  A 170 ( 1.3A)
TYR  A 146 ( 1.3A)
 1.32A 2bteD-5w0aA:
undetectable		 2bteD-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_A_LEUA1301_0
(LEUCYL-TRNA
SYNTHETASE)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		4 / 7 TYR A  38
ASP A  35
TYR A 170
TYR A 146
 TYR  A  38 ( 1.3A)
ASP  A  35 ( 0.6A)
TYR  A 170 ( 1.3A)
TYR  A 146 ( 1.3A)
 1.29A 2bytA-5w0aA:
undetectable		 2bytA-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_D_LEUD1601_0
(LEUCYL-TRNA
SYNTHETASE)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		4 / 7 TYR A  38
ASP A  35
TYR A 170
TYR A 146
 TYR  A  38 ( 1.3A)
ASP  A  35 ( 0.6A)
TYR  A 170 ( 1.3A)
TYR  A 146 ( 1.3A)
 1.29A 2bytD-5w0aA:
undetectable		 2bytD-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 GLY A 167
ARG A  39
TYR A 110
 GLY  A 167 ( 0.0A)
ARG  A  39 ( 0.6A)
TYR  A 110 ( 1.3A)
 0.75A 2opxA-5w0aA:
undetectable		 2opxA-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		4 / 8 TYR A  38
ASP A  35
TYR A 170
TYR A 146
 TYR  A  38 ( 1.3A)
ASP  A  35 ( 0.6A)
TYR  A 170 ( 1.3A)
TYR  A 146 ( 1.3A)
 1.30A 2v0gA-5w0aA:
undetectable		 2v0gA-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_D_LEUD1883_0
(AMINOACYL-TRNA
SYNTHETASE)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		4 / 5 TYR A  38
ASP A  35
TYR A 170
TYR A 146
 TYR  A  38 ( 1.3A)
ASP  A  35 ( 0.6A)
TYR  A 170 ( 1.3A)
TYR  A 146 ( 1.3A)
 1.38A 2v0gD-5w0aA:
undetectable		 2v0gD-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 THR A   5
PRO A   8
THR A   7
 THR  A   5 ( 0.8A)
PRO  A   8 ( 1.1A)
THR  A   7 ( 0.8A)
 0.81A 316dC-5w0aA:
undetectable		 316dC-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		4 / 8 GLY A 113
ASP A 117
GLY A 116
VAL A  33
 GLY  A 113 ( 0.0A)
ASP  A 117 ( 0.5A)
GLY  A 116 ( 0.0A)
VAL  A  33 ( 0.6A)
 0.78A 4c5nC-5w0aA:
undetectable		 4c5nC-5w0aA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5w0a GLUCANASE
(Trichoderma
harzianum) 		4 / 8 ASN A 142
GLY A 143
PHE A 130
ILE A 199
 ASN  A 142 ( 0.6A)
GLY  A 143 ( 0.0A)
PHE  A 130 ( 1.3A)
ILE  A 199 ( 0.7A)
 0.93A 4fglD-5w0aA:
undetectable		 4fglD-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		5 / 12 GLY A 140
LEU A 330
ILE A 319
ASN A 352
LEU A 134
 GLY  A 140 ( 0.0A)
LEU  A 330 ( 0.5A)
ILE  A 319 ( 0.7A)
ASN  A 352 ( 0.6A)
LEU  A 134 ( 0.6A)
 1.05A 4fr0A-5w0aA:
undetectable		 4fr0A-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IPM_A_ACTA503_0
(GH7 FAMILY PROTEIN)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		9 / 9 ASN A 142
ALA A 144
TYR A 146
TYR A 170
ASP A 172
GLU A 196
ASP A 198
GLU A 201
TRP A 320
 ASN  A 142 ( 0.6A)
ALA  A 144 ( 0.0A)
TYR  A 146 ( 1.3A)
TYR  A 170 ( 1.3A)
ASP  A 172 ( 0.5A)
GLU  A 196 ( 0.6A)
ASP  A 198 (-0.6A)
GLU  A 201 (-0.5A)
TRP  A 320 ( 0.5A)
 0.55A 4ipmA-5w0aA:
48.2		 4ipmA-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		4 / 5 GLY A   4
THR A   5
HIS A  42
GLU A  73
 GLY  A   4 ( 0.0A)
THR  A   5 ( 0.8A)
HIS  A  42 ( 1.0A)
GLU  A  73 ( 0.6A)
 0.44A 4v20A-5w0aA:
50.4		 4v20A-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP1_A_LDPA708_1
(DOPAMINE
TRANSPORTER, ISOFORM
B)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		5 / 10 VAL A 132
ASP A 133
PHE A 249
SER A 204
SER A 135
 VAL  A 132 ( 0.6A)
ASP  A 133 ( 0.6A)
PHE  A 249 ( 1.3A)
SER  A 204 ( 0.0A)
SER  A 135 ( 0.0A)
 1.39A 4xp1A-5w0aA:
undetectable		 4xp1A-5w0aA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHD_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		4 / 4 ARG A 271
PHE A 209
ASP A 198
LEU A 137
 ARG  A 271 ( 0.6A)
PHE  A 209 ( 1.3A)
ASP  A 198 (-0.6A)
LEU  A 137 ( 0.6A)
 1.45A 5uhdC-5w0aA:
0.3		 5uhdC-5w0aA:
4.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		3 / 3 LYS A   1
ASN A 160
SER A 168
 GLN  A   1 ( 0.0A)
ASN  A 160 ( 0.6A)
SER  A 168 ( 0.0A)
 1.13A 5yw0A-5w0aA:
undetectable		 5yw0A-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		5 / 12 GLY A 163
ASN A 153
ALA A 156
ASP A 115
LEU A 112
 GLY  A 163 ( 0.0A)
ASN  A 153 ( 0.6A)
ALA  A 156 (-0.0A)
ASP  A 115 ( 0.5A)
LEU  A 112 ( 0.6A)
 0.96A 6b3aA-5w0aA:
undetectable		 6b3aA-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		5 / 12 GLY A 163
ASN A 153
ALA A 156
ASP A 115
LEU A 112
 GLY  A 163 ( 0.0A)
ASN  A 153 ( 0.6A)
ALA  A 156 (-0.0A)
ASP  A 115 ( 0.5A)
LEU  A 112 ( 0.6A)
 0.95A 6b3bA-5w0aA:
undetectable		 6b3bA-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		5 / 10 PRO A 294
LEU A 302
SER A 213
ILE A 290
GLY A 225
 PRO  A 294 ( 1.1A)
LEU  A 302 ( 0.6A)
SER  A 213 ( 0.0A)
ILE  A 290 ( 0.7A)
GLY  A 225 ( 0.0A)
 1.10A 6dlzA-5w0aA:
undetectable
6dlzD-5w0aA:
undetectable		 6dlzA-5w0aA:
20.93
6dlzD-5w0aA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		5 / 10 ILE A 290
GLY A 225
PRO A 294
LEU A 302
SER A 213
 ILE  A 290 ( 0.7A)
GLY  A 225 ( 0.0A)
PRO  A 294 ( 1.1A)
LEU  A 302 ( 0.6A)
SER  A 213 ( 0.0A)
 1.10A 6dlzB-5w0aA:
undetectable
6dlzC-5w0aA:
undetectable		 6dlzB-5w0aA:
20.93
6dlzC-5w0aA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		5 / 10 PRO A 294
LEU A 302
SER A 213
ILE A 290
GLY A 225
 PRO  A 294 ( 1.1A)
LEU  A 302 ( 0.6A)
SER  A 213 ( 0.0A)
ILE  A 290 ( 0.7A)
GLY  A 225 ( 0.0A)
 1.10A 6dm1A-5w0aA:
undetectable
6dm1D-5w0aA:
undetectable		 6dm1A-5w0aA:
20.93
6dm1D-5w0aA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5w0a GLUCANASE
(Trichoderma
harzianum) 		5 / 10 ILE A 290
GLY A 225
PRO A 294
LEU A 302
SER A 213
 ILE  A 290 ( 0.7A)
GLY  A 225 ( 0.0A)
PRO  A 294 ( 1.1A)
LEU  A 302 ( 0.6A)
SER  A 213 ( 0.0A)
 1.10A 6dm1B-5w0aA:
undetectable
6dm1C-5w0aA:
undetectable		 6dm1B-5w0aA:
20.93
6dm1C-5w0aA:
20.93