SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5w0h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 5w0h SPLICING FACTOR U2AF
65 KDA SUBUNIT
(Homo
sapiens) 		5 / 12 PHE A 262
ILE A 263
GLY A 264
VAL A 332
VAL A 275
 None
 0.93A 3fpjA-5w0hA:
undetectable		 3fpjA-5w0hA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 5w0h SPLICING FACTOR U2AF
65 KDA SUBUNIT
(Homo
sapiens) 		3 / 3 LYS A 329
ASP A 327
ILE A 263
 None
 0.82A 5kc4E-5w0hA:
undetectable		 5kc4E-5w0hA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5w0h SPLICING FACTOR U2AF
65 KDA SUBUNIT
(Homo
sapiens) 		3 / 3 GLU A 306
HIS A 259
ARG A 334
 None
 0.79A 5uunA-5w0hA:
undetectable		 5uunA-5w0hA:
undetectable