SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5w0s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_1
(PROTEIN (PROTEASE))		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 11 LEU A 222
VAL A 276
ILE A 325
PRO A 279
ILE A 250
 None
 0.93A 1c6yA-5w0sA:
undetectable		 1c6yA-5w0sA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 12 ALA A 507
ALA A 508
LEU A  95
ALA A  96
VAL A 422
 None
 0.82A 1fm6A-5w0sA:
undetectable		 1fm6A-5w0sA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_1
(HIV-1 PROTEASE)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 9 ASP A 495
GLY A 415
VAL A 411
ILE A 489
GLY A 492
 None
 1.00A 1hpvA-5w0sA:
undetectable		 1hpvA-5w0sA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_1
(HIV-1 PROTEASE)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 10 LEU A 222
VAL A 276
ILE A 325
PRO A 279
ILE A 250
 None
 0.93A 1hsgA-5w0sA:
undetectable		 1hsgA-5w0sA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_2
(ASPARTYLPROTEASE)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 9 LEU A 222
VAL A 276
ILE A 325
PRO A 279
ILE A 250
 None
 0.93A 1ohrB-5w0sA:
undetectable		 1ohrB-5w0sA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_2
(POL POLYPROTEIN)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		4 / 7 ASP A 495
VAL A 411
GLY A 148
ILE A 162
 None
 0.70A 1t7iB-5w0sA:
undetectable		 1t7iB-5w0sA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_2
(POL POLYPROTEIN)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		4 / 7 ASP A 495
VAL A 411
GLY A 148
ILE A 162
 None
 0.71A 1t7jB-5w0sA:
undetectable		 1t7jB-5w0sA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 12 ALA A 507
ALA A 508
LEU A  95
ALA A  96
VAL A 422
 None
 0.83A 1xlsA-5w0sA:
undetectable		 1xlsA-5w0sA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 12 ALA A 507
ALA A 508
LEU A  95
ALA A  96
VAL A 422
 None
 0.84A 1xlsB-5w0sA:
undetectable		 1xlsB-5w0sA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 12 ALA A 507
ALA A 508
LEU A  95
ALA A  96
VAL A 422
 None
 0.83A 1xlsC-5w0sA:
undetectable		 1xlsC-5w0sA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 12 ALA A 507
ALA A 508
LEU A  95
ALA A  96
VAL A 422
 None
 0.83A 1xlsD-5w0sA:
undetectable		 1xlsD-5w0sA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BPX_B_MK1B902_2
(HIV-1 PROTEASE)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 12 ASP A 495
GLY A 415
VAL A 411
ILE A 489
GLY A 492
 None
 0.83A 2bpxB-5w0sA:
undetectable		 2bpxB-5w0sA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_B_THRB402_0
(ASPARTOKINASE)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 9 ILE A 175
ILE A 333
GLU A 178
ALA A 377
THR A 331
 None
 1.34A 2dtjA-5w0sA:
undetectable
2dtjB-5w0sA:
undetectable		 2dtjA-5w0sA:
17.30
2dtjB-5w0sA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		4 / 8 ALA A 423
VAL A 422
LEU A 504
THR A 500
 None
 0.85A 2it4A-5w0sA:
undetectable		 2it4A-5w0sA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1498_1
(CYTOCHROME P450 3A4)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 11 ARG A  58
ALA A  78
THR A  93
GLU A  59
LEU A  23
 None
 1.30A 2v0mD-5w0sA:
undetectable		 2v0mD-5w0sA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 9 LEU A 221
LEU A 237
ALA A 275
LEU A 262
ALA A 258
 None
 1.03A 2vcvD-5w0sA:
undetectable		 2vcvD-5w0sA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 9 LEU A 221
LEU A 237
ALA A 275
LEU A 262
ALA A 258
 None
 1.03A 2vcvE-5w0sA:
undetectable		 2vcvE-5w0sA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		4 / 7 LEU A 221
ALA A 275
LEU A 262
ALA A 258
 None
 0.81A 2vcvG-5w0sA:
undetectable		 2vcvG-5w0sA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 9 LEU A 221
LEU A 237
ALA A 275
LEU A 262
ALA A 258
 None
 1.04A 2vcvH-5w0sA:
undetectable		 2vcvH-5w0sA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_I_ASDI1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 9 LEU A 221
LEU A 237
ALA A 275
LEU A 262
ALA A 258
 None
 0.99A 2vcvI-5w0sA:
undetectable		 2vcvI-5w0sA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 12 GLY A 192
GLY A 375
ALA A 373
LEU A 372
VAL A 323
 None
 0.98A 2zulA-5w0sA:
undetectable		 2zulA-5w0sA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 12 VAL A 107
LEU A 104
GLY A 103
ILE A  99
THR A 516
 None
 1.09A 3bjwF-5w0sA:
undetectable		 3bjwF-5w0sA:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 12 LEU A 237
ALA A 258
THR A 330
VAL A 323
ILE A 220
 None
 0.99A 3c6gA-5w0sA:
undetectable		 3c6gA-5w0sA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 10 ASP A 495
GLY A 415
VAL A 411
ILE A 489
GLY A 492
 None
 0.83A 3ekpD-5w0sA:
undetectable		 3ekpD-5w0sA:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_1
(PROTEASE)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 12 ALA A 251
ILE A 301
VAL A 300
ILE A 292
ILE A 249
 None
 0.86A 3ekqA-5w0sA:
undetectable		 3ekqA-5w0sA:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_2
(PROTEASE)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 9 LEU A 222
VAL A 276
ILE A 325
PRO A 279
ILE A 250
 None
 0.98A 3ekqB-5w0sA:
undetectable		 3ekqB-5w0sA:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_2
(PROTEASE)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 12 ALA A 251
ILE A 301
VAL A 300
ILE A 292
ILE A 249
 None
 0.95A 3ekwB-5w0sA:
undetectable		 3ekwB-5w0sA:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 12 ALA A 507
ALA A 508
LEU A  95
ALA A  96
VAL A 422
 None
 0.84A 3h0aA-5w0sA:
undetectable		 3h0aA-5w0sA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_1
(HIV-1 PROTEASE)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 9 ALA A 143
VAL A 407
GLY A 148
ILE A 150
PRO A 496
 None
 1.14A 3spkA-5w0sA:
undetectable		 3spkA-5w0sA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		4 / 5 GLY A  53
VAL A  54
ASP A  52
THR A  50
 None
 1.26A 3vqrB-5w0sA:
undetectable		 3vqrB-5w0sA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		3 / 3 TYR A 485
THR A 468
GLU A 460
 None
 0.83A 4df3A-5w0sA:
undetectable		 4df3A-5w0sA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 12 LEU A  17
ASN A  21
LEU A  23
ALA A  24
ALA A 507
 None
 1.10A 4fn9A-5w0sA:
undetectable		 4fn9A-5w0sA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4II8_A_010A210_0
(LYSOZYME C)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		4 / 7 ASP A 115
GLN A 436
ASN A 112
ILE A 515
 None
 1.27A 4ii8A-5w0sA:
undetectable		 4ii8A-5w0sA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XNX_A_41XA707_1
(TRANSPORTER)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 11 ALA A 106
VAL A 107
GLY A 119
VAL A 442
GLY A 103
 None
 1.13A 4xnxA-5w0sA:
undetectable		 4xnxA-5w0sA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YJI_A_TYLA502_1
(ARYL ACYLAMIDASE)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		4 / 7 THR A 299
GLY A 297
ALA A 293
ILE A 342
 None
 0.67A 4yjiA-5w0sA:
undetectable		 4yjiA-5w0sA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 12 ILE A 249
ALA A 274
THR A 330
ILE A 332
ILE A 250
 None
 1.03A 5e8qA-5w0sA:
undetectable		 5e8qA-5w0sA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 10 ALA A 165
GLY A 148
HIS A 401
THR A 403
ILE A 144
 None
 1.18A 5eeuF-5w0sA:
undetectable
5eeuG-5w0sA:
undetectable		 5eeuF-5w0sA:
10.23
5eeuG-5w0sA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 12 ALA A 165
GLY A 148
HIS A 401
THR A 403
ILE A 144
 None
 1.15A 5eeuI-5w0sA:
undetectable
5eeuJ-5w0sA:
undetectable		 5eeuI-5w0sA:
10.23
5eeuJ-5w0sA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 10 ALA A 165
GLY A 148
HIS A 401
THR A 403
ILE A 144
 None
 1.18A 5eevF-5w0sA:
undetectable
5eevG-5w0sA:
undetectable		 5eevF-5w0sA:
10.23
5eevG-5w0sA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 12 ALA A 165
GLY A 148
HIS A 401
THR A 403
ILE A 144
 None
 1.15A 5eevI-5w0sA:
undetectable
5eevJ-5w0sA:
undetectable		 5eevI-5w0sA:
10.23
5eevJ-5w0sA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 10 ALA A 165
GLY A 148
HIS A 401
THR A 403
ILE A 144
 None
 1.18A 5eewF-5w0sA:
undetectable
5eewG-5w0sA:
undetectable		 5eewF-5w0sA:
10.23
5eewG-5w0sA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 12 ALA A 165
GLY A 148
HIS A 401
THR A 403
ILE A 144
 None
 1.15A 5eewI-5w0sA:
undetectable
5eewJ-5w0sA:
undetectable		 5eewI-5w0sA:
10.23
5eewJ-5w0sA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 10 ALA A 165
GLY A 148
HIS A 401
THR A 403
ILE A 144
 None
 1.18A 5eexF-5w0sA:
undetectable
5eexG-5w0sA:
undetectable		 5eexF-5w0sA:
10.23
5eexG-5w0sA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 10 ALA A 165
GLY A 148
HIS A 401
THR A 403
ILE A 144
 None
 1.18A 5eeyF-5w0sA:
undetectable
5eeyG-5w0sA:
undetectable		 5eeyF-5w0sA:
10.23
5eeyG-5w0sA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 10 ALA A 165
GLY A 148
HIS A 401
THR A 403
ILE A 144
 None
 1.18A 5eezF-5w0sA:
undetectable
5eezG-5w0sA:
undetectable		 5eezF-5w0sA:
10.23
5eezG-5w0sA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 10 ALA A 165
GLY A 148
HIS A 401
THR A 403
ILE A 144
 None
 1.18A 5ef0F-5w0sA:
undetectable
5ef0G-5w0sA:
undetectable		 5ef0F-5w0sA:
10.23
5ef0G-5w0sA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 10 ALA A 165
GLY A 148
HIS A 401
THR A 403
ILE A 144
 None
 1.17A 5ef1F-5w0sA:
undetectable
5ef1G-5w0sA:
undetectable		 5ef1F-5w0sA:
10.23
5ef1G-5w0sA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 10 ALA A 165
GLY A 148
HIS A 401
THR A 403
ILE A 144
 None
 1.18A 5ef2F-5w0sA:
undetectable
5ef2G-5w0sA:
undetectable		 5ef2F-5w0sA:
10.23
5ef2G-5w0sA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 10 ALA A 165
GLY A 148
HIS A 401
THR A 403
ILE A 144
 None
 1.18A 5ef3F-5w0sA:
undetectable
5ef3G-5w0sA:
undetectable		 5ef3F-5w0sA:
10.23
5ef3G-5w0sA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 12 ILE A 162
GLY A 159
THR A 149
ASP A 155
ALA A 399
 None
 1.24A 5hw4A-5w0sA:
undetectable		 5hw4A-5w0sA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_2
(PROTEASE E35D-SQV)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 9 LEU A 222
VAL A 276
ILE A 325
PRO A 279
ILE A 250
 None
 1.04A 5kqxB-5w0sA:
undetectable		 5kqxB-5w0sA:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		5 / 12 ALA A 223
LEU A 221
ILE A 220
LEU A 200
ILE A 227
 None
 1.00A 5m24A-5w0sA:
undetectable		 5m24A-5w0sA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 5w0s 60 KDA CHAPERONIN
(Escherichia
coli) 		3 / 3 LYS A   4
VAL A 521
ASP A 523
 None
 0.59A 6fgdA-5w0sA:
undetectable		 6fgdA-5w0sA:
23.27