SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5w0x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 5w0x TIP41-LIKE PROTEIN
(Mus
musculus) 		4 / 5 GLU A 152
THR A 199
LEU A 181
LEU A 183
 None
 1.08A 1u18B-5w0xA:
undetectable		 1u18B-5w0xA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5w0x TIP41-LIKE PROTEIN
(Mus
musculus) 		4 / 6 TYR A 202
SER A 177
ALA A 205
SER A 178
 None
 1.16A 1yvpB-5w0xA:
undetectable		 1yvpB-5w0xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1477_2
(NEURAMINIDASE)		 5w0x TIP41-LIKE PROTEIN
(Mus
musculus) 		4 / 5 LEU A 182
ARG A 217
ARG A 184
ILE A 244
 None
 1.42A 2cmlA-5w0xA:
undetectable		 2cmlA-5w0xA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2477_2
(NEURAMINIDASE)		 5w0x TIP41-LIKE PROTEIN
(Mus
musculus) 		4 / 5 LEU A 182
ARG A 217
ARG A 184
ILE A 244
 None
 1.40A 2cmlB-5w0xA:
undetectable		 2cmlB-5w0xA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3477_2
(NEURAMINIDASE)		 5w0x TIP41-LIKE PROTEIN
(Mus
musculus) 		4 / 5 LEU A 182
ARG A 217
ARG A 184
ILE A 244
 None
 1.37A 2cmlC-5w0xA:
undetectable		 2cmlC-5w0xA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4477_2
(NEURAMINIDASE)		 5w0x TIP41-LIKE PROTEIN
(Mus
musculus) 		4 / 5 LEU A 182
ARG A 217
ARG A 184
ILE A 244
 None
 1.38A 2cmlD-5w0xA:
undetectable		 2cmlD-5w0xA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 5w0x TIP41-LIKE PROTEIN
(Mus
musculus) 		4 / 7 VAL A 227
LEU A 242
MET A 196
ILE A 194
 None
 0.80A 3rfmA-5w0xA:
undetectable		 3rfmA-5w0xA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_2
(NEURAMINIDASE)		 5w0x TIP41-LIKE PROTEIN
(Mus
musculus) 		4 / 5 LEU A 182
ARG A 217
ARG A 184
ILE A 244
 None
 1.43A 3ticA-5w0xA:
undetectable		 3ticA-5w0xA:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5w0x TIP41-LIKE PROTEIN
(Mus
musculus) 		4 / 7 ILE A  65
VAL A  54
PHE A 179
ASP A  12
 None
 1.24A 4iarA-5w0xA:
undetectable		 4iarA-5w0xA:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5w0x TIP41-LIKE PROTEIN
(Mus
musculus) 		4 / 7 VAL A 227
ILE A 238
ARG A 217
ILE A 194
 None
 0.93A 4lv9B-5w0xA:
undetectable		 4lv9B-5w0xA:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)		 5w0x TIP41-LIKE PROTEIN
(Mus
musculus) 		5 / 12 ASP A 115
VAL A 248
ALA A 247
TYR A 214
SER A 216
 None
 1.11A 4mm8A-5w0xA:
undetectable		 4mm8A-5w0xA:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 5w0x TIP41-LIKE PROTEIN
(Mus
musculus) 		5 / 10 ASP A 115
VAL A 248
ALA A 247
TYR A 214
SER A 216
 None
 1.22A 4mmdA-5w0xA:
undetectable		 4mmdA-5w0xA:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ACL_A_SASA1111_1
(MCG)		 5w0x TIP41-LIKE PROTEIN
(Mus
musculus) 		4 / 7 SER A 216
TYR A 214
GLU A 218
PHE A 185
 None
 0.77A 5aclA-5w0xA:
undetectable		 5aclA-5w0xA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_B_SAMB301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5w0x TIP41-LIKE PROTEIN
(Mus
musculus) 		5 / 12 ALA A  72
PRO A  46
PHE A 156
GLY A  51
THR A  25
 None
 1.30A 5hfjB-5w0xA:
undetectable		 5hfjB-5w0xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5w0x TIP41-LIKE PROTEIN
(Mus
musculus) 		5 / 12 ALA A  72
PRO A  46
PHE A 156
GLY A  51
THR A  25
 None
 1.30A 5hfjC-5w0xA:
undetectable		 5hfjC-5w0xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_D_SAMD301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5w0x TIP41-LIKE PROTEIN
(Mus
musculus) 		5 / 12 ALA A  72
PRO A  46
PHE A 156
GLY A  51
THR A  25
 None
 1.23A 5hfjD-5w0xA:
undetectable		 5hfjD-5w0xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5w0x TIP41-LIKE PROTEIN
(Mus
musculus) 		5 / 12 ALA A  72
PRO A  46
PHE A 156
GLY A  51
THR A  25
 None
 1.21A 5hfjG-5w0xA:
undetectable		 5hfjG-5w0xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5w0x TIP41-LIKE PROTEIN
(Mus
musculus) 		5 / 12 ALA A  72
PRO A  46
PHE A 156
GLY A  51
THR A  25
 None
 1.31A 5hfjH-5w0xA:
undetectable		 5hfjH-5w0xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_2
(TUBULIN BETA CHAIN)		 5w0x TIP41-LIKE PROTEIN
(Mus
musculus) 		4 / 5 LEU A 183
THR A 215
PRO A 235
ARG A 188
 None
 1.35A 6ew0B-5w0xA:
undetectable		 6ew0B-5w0xA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_2
(TUBULIN BETA CHAIN)		 5w0x TIP41-LIKE PROTEIN
(Mus
musculus) 		4 / 5 LEU A 183
THR A 215
PRO A 235
ARG A 188
 None
 1.35A 6ew0D-5w0xA:
undetectable		 6ew0D-5w0xA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_2
(TUBULIN BETA CHAIN)		 5w0x TIP41-LIKE PROTEIN
(Mus
musculus) 		4 / 5 LEU A 183
THR A 215
PRO A 235
ARG A 188
 None
 1.35A 6ew0H-5w0xA:
undetectable		 6ew0H-5w0xA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_2
(TUBULIN BETA CHAIN)		 5w0x TIP41-LIKE PROTEIN
(Mus
musculus) 		4 / 5 LEU A 183
THR A 215
PRO A 235
ARG A 188
 None
 1.35A 6ew0I-5w0xA:
undetectable		 6ew0I-5w0xA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 5w0x TIP41-LIKE PROTEIN
(Mus
musculus) 		5 / 12 TRP A 110
ASP A 109
VAL A  76
PHE A 185
ASN A 197
 None
 1.25A 6h7mB-5w0xA:
undetectable		 6h7mB-5w0xA:
17.58