SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5w1j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 1c9sA-5w1jA:
undetectable
1c9sK-5w1jA:
undetectable
1c9sA-5w1jA:
8.72
1c9sK-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.25A 1c9sB-5w1jA:
undetectable
1c9sC-5w1jA:
undetectable
1c9sB-5w1jA:
8.72
1c9sC-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 1c9sD-5w1jA:
undetectable
1c9sE-5w1jA:
undetectable
1c9sD-5w1jA:
8.72
1c9sE-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.26A 1c9sE-5w1jA:
undetectable
1c9sF-5w1jA:
undetectable
1c9sE-5w1jA:
8.72
1c9sF-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 1c9sG-5w1jA:
undetectable
1c9sH-5w1jA:
undetectable
1c9sG-5w1jA:
8.72
1c9sH-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 1c9sH-5w1jA:
undetectable
1c9sI-5w1jA:
undetectable
1c9sH-5w1jA:
8.72
1c9sI-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 1c9sJ-5w1jA:
undetectable
1c9sK-5w1jA:
undetectable
1c9sJ-5w1jA:
8.72
1c9sK-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.22A 1c9sO-5w1jA:
undetectable
1c9sP-5w1jA:
undetectable
1c9sO-5w1jA:
8.72
1c9sP-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.22A 1gtfA-5w1jA:
undetectable
1gtfK-5w1jA:
undetectable
1gtfA-5w1jA:
8.72
1gtfK-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.26A 1gtfC-5w1jA:
undetectable
1gtfD-5w1jA:
undetectable
1gtfC-5w1jA:
8.72
1gtfD-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.25A 1gtfE-5w1jA:
undetectable
1gtfF-5w1jA:
undetectable
1gtfE-5w1jA:
8.72
1gtfF-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 1gtfG-5w1jA:
undetectable
1gtfH-5w1jA:
undetectable
1gtfG-5w1jA:
8.72
1gtfH-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 1gtfH-5w1jA:
undetectable
1gtfI-5w1jA:
undetectable
1gtfH-5w1jA:
8.72
1gtfI-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.22A 1gtfI-5w1jA:
undetectable
1gtfJ-5w1jA:
undetectable
1gtfI-5w1jA:
8.72
1gtfJ-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.20A 1gtfP-5w1jA:
undetectable
1gtfQ-5w1jA:
undetectable
1gtfP-5w1jA:
8.72
1gtfQ-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.17A 1gtfT-5w1jA:
undetectable
1gtfU-5w1jA:
undetectable
1gtfT-5w1jA:
8.72
1gtfU-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 11 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.18A 1gtfU-5w1jA:
undetectable
1gtfV-5w1jA:
undetectable
1gtfU-5w1jA:
8.72
1gtfV-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 1gtfL-5w1jA:
undetectable
1gtfV-5w1jA:
undetectable
1gtfL-5w1jA:
8.72
1gtfV-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.21A 1gtnB-5w1jA:
undetectable
1gtnC-5w1jA:
undetectable
1gtnB-5w1jA:
8.72
1gtnC-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 1gtnG-5w1jA:
undetectable
1gtnH-5w1jA:
undetectable
1gtnG-5w1jA:
8.72
1gtnH-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 1gtnH-5w1jA:
undetectable
1gtnI-5w1jA:
undetectable
1gtnH-5w1jA:
8.72
1gtnI-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 11 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.18A 1gtnM-5w1jA:
undetectable
1gtnN-5w1jA:
undetectable
1gtnM-5w1jA:
8.72
1gtnN-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.17A 1gtnN-5w1jA:
undetectable
1gtnO-5w1jA:
undetectable
1gtnN-5w1jA:
8.72
1gtnO-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.18A 1gtnS-5w1jA:
undetectable
1gtnT-5w1jA:
undetectable
1gtnS-5w1jA:
8.72
1gtnT-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_2
(HIV-II PROTEASE)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 ALA A 125
ILE A 254
GLY A 448
ILE A 445
ILE A 114
None
0.90A 1hshB-5w1jA:
undetectable
1hshB-5w1jA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_0
(HYPOTHETICAL PROTEIN
RV2118C)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 12 GLY A 116
GLY A 118
SER A 119
ALA A 123
LEU A 124
FAD  A 601 (-3.1A)
FAD  A 601 (-2.9A)
FAD  A 601 (-3.8A)
None
None
0.89A 1i9gA-5w1jA:
3.0
1i9gA-5w1jA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_A_MTXA1278_1
(PTERIDINE REDUCTASE
2)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 SER A 131
ASP A 459
LEU A  53
LEU A  11
THR A  70
None
1.36A 1mxfA-5w1jA:
2.4
1mxfA-5w1jA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_B_MTXB2278_1
(PTERIDINE REDUCTASE
2)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 11 SER A 131
ASP A 459
LEU A  53
LEU A  11
THR A  70
None
1.40A 1mxfB-5w1jA:
2.3
1mxfB-5w1jA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_C_MTXC3278_1
(PTERIDINE REDUCTASE
2)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 11 SER A 131
ASP A 459
LEU A  53
LEU A  11
THR A  70
None
1.40A 1mxfC-5w1jA:
2.4
1mxfC-5w1jA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_D_MTXD4278_1
(PTERIDINE REDUCTASE
2)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 11 SER A 131
ASP A 459
LEU A  53
LEU A  11
THR A  70
None
1.40A 1mxfD-5w1jA:
2.4
1mxfD-5w1jA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.27A 1utdA-5w1jA:
undetectable
1utdB-5w1jA:
undetectable
1utdA-5w1jA:
8.72
1utdB-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.22A 1utdC-5w1jA:
undetectable
1utdD-5w1jA:
undetectable
1utdC-5w1jA:
8.72
1utdD-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 1utdG-5w1jA:
undetectable
1utdH-5w1jA:
undetectable
1utdG-5w1jA:
8.72
1utdH-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 1utdA-5w1jA:
undetectable
1utdK-5w1jA:
undetectable
1utdA-5w1jA:
8.72
1utdK-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 11 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 1utdM-5w1jA:
undetectable
1utdN-5w1jA:
undetectable
1utdM-5w1jA:
8.72
1utdN-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.21A 1utdN-5w1jA:
undetectable
1utdO-5w1jA:
undetectable
1utdN-5w1jA:
8.72
1utdO-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.17A 1utdR-5w1jA:
undetectable
1utdS-5w1jA:
undetectable
1utdR-5w1jA:
8.72
1utdS-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_2
(POL PROTEIN)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
4 / 7 ARG A 462
ASP A 459
ASP A  52
GLY A  59
None
0.92A 2fxdB-5w1jA:
undetectable
2fxdB-5w1jA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
4 / 5 PHE A 563
PHE A 577
HIS A 537
VAL A 533
None
1.20A 2lh6A-5w1jA:
undetectable
2lh6A-5w1jA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_2
(PROTEASE)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 LEU A 138
VAL A 255
GLY A 401
VAL A 113
ILE A 115
None
None
None
None
FAD  A 601 (-4.7A)
0.89A 2o4pB-5w1jA:
undetectable
2o4pB-5w1jA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
4 / 8 MET A 328
SER A 484
TYR A 478
HIS A 537
None
1.28A 2v0gA-5w1jA:
undetectable
2v0gA-5w1jA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_C_IBPC1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 LEU A 208
VAL A 157
GLY A 153
GLY A 151
ARG A 213
None
1.27A 2wd9C-5w1jA:
undetectable
2wd9C-5w1jA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 12 ILE A 114
GLY A 121
GLY A 448
LEU A 451
ILE A 430
None
0.99A 2y7kD-5w1jA:
0.8
2y7kD-5w1jA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 12 ILE A 115
GLY A 228
GLY A 401
LEU A 402
ILE A 230
FAD  A 601 (-4.7A)
FAD  A 601 (-3.8A)
None
None
None
1.20A 2y7kD-5w1jA:
0.8
2y7kD-5w1jA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_0
(HYPOTHETICAL PROTEIN)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 12 GLY A 116
GLY A 118
SER A 119
ALA A 123
LEU A 124
FAD  A 601 (-3.1A)
FAD  A 601 (-2.9A)
FAD  A 601 (-3.8A)
None
None
0.93A 2yvlA-5w1jA:
3.0
2yvlA-5w1jA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_E_VDYE6178_1
(VITAMIN D
HYDROXYLASE)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
6 / 12 THR A 250
ASN A 247
ILE A 115
ALA A 256
VAL A 414
LEU A 402
None
None
FAD  A 601 (-4.7A)
None
None
None
1.42A 3a51E-5w1jA:
undetectable
3a51E-5w1jA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_2
(HIV-1 PROTEASE)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 LEU A 138
VAL A 255
VAL A 231
VAL A 113
ILE A 115
None
None
None
None
FAD  A 601 (-4.7A)
0.88A 3oxwD-5w1jA:
undetectable
3oxwD-5w1jA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_1
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 11 VAL A 292
CYH A 291
LEU A 290
THR A 289
VAL A 391
None
0.98A 4e0fA-5w1jA:
undetectable
4e0fA-5w1jA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_B_BEZB1000_0
(BENZOATE-COENZYME A
LIGASE)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 ALA A 125
ALA A 256
GLY A 116
GLY A 120
ILE A 430
None
None
FAD  A 601 (-3.1A)
FAD  A 601 (-3.7A)
None
1.15A 4eatB-5w1jA:
undetectable
4eatB-5w1jA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
4 / 7 THR A 470
GLY A 479
VAL A 538
GLY A 535
None
0.79A 4forA-5w1jA:
undetectable
4forA-5w1jA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_A_LURA201_1
(TRANSTHYRETIN)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
3 / 3 LYS A 222
LEU A 224
ALA A 136
None
0.54A 4iizA-5w1jA:
undetectable
4iizA-5w1jA:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 12 CYH A 291
LEU A 388
ALA A 390
VAL A 312
ILE A 336
None
1.12A 4x1yB-5w1jA:
undetectable
4x1yB-5w1jA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 12 ASP A 139
LEU A 137
GLU A 259
GLY A 120
ALA A 123
FAD  A 601 (-3.0A)
None
None
FAD  A 601 (-3.7A)
None
1.15A 4xe5A-5w1jA:
1.5
4xe5A-5w1jA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5eeuB-5w1jA:
undetectable
5eeuC-5w1jA:
undetectable
5eeuB-5w1jA:
8.72
5eeuC-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5eeuE-5w1jA:
undetectable
5eeuF-5w1jA:
undetectable
5eeuE-5w1jA:
8.72
5eeuF-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5eeuG-5w1jA:
undetectable
5eeuH-5w1jA:
undetectable
5eeuG-5w1jA:
8.72
5eeuH-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.25A 5eeuH-5w1jA:
undetectable
5eeuI-5w1jA:
undetectable
5eeuH-5w1jA:
8.72
5eeuI-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.25A 5eeuJ-5w1jA:
undetectable
5eeuK-5w1jA:
undetectable
5eeuJ-5w1jA:
8.72
5eeuK-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5eeuA-5w1jA:
undetectable
5eeuK-5w1jA:
undetectable
5eeuA-5w1jA:
8.72
5eeuK-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5eeuN-5w1jA:
undetectable
5eeuO-5w1jA:
undetectable
5eeuN-5w1jA:
8.72
5eeuO-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.21A 5eeuP-5w1jA:
undetectable
5eeuQ-5w1jA:
undetectable
5eeuP-5w1jA:
8.72
5eeuQ-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5eeuR-5w1jA:
undetectable
5eeuS-5w1jA:
undetectable
5eeuR-5w1jA:
8.72
5eeuS-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.20A 5eeuS-5w1jA:
undetectable
5eeuT-5w1jA:
undetectable
5eeuS-5w1jA:
8.72
5eeuT-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5eeuT-5w1jA:
undetectable
5eeuU-5w1jA:
undetectable
5eeuT-5w1jA:
8.72
5eeuU-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5eeuU-5w1jA:
undetectable
5eeuV-5w1jA:
undetectable
5eeuU-5w1jA:
8.72
5eeuV-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5eevB-5w1jA:
undetectable
5eevC-5w1jA:
undetectable
5eevB-5w1jA:
8.72
5eevC-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5eevE-5w1jA:
undetectable
5eevF-5w1jA:
undetectable
5eevE-5w1jA:
8.72
5eevF-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5eevG-5w1jA:
undetectable
5eevH-5w1jA:
undetectable
5eevG-5w1jA:
8.72
5eevH-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.25A 5eevH-5w1jA:
undetectable
5eevI-5w1jA:
undetectable
5eevH-5w1jA:
8.72
5eevI-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.25A 5eevJ-5w1jA:
undetectable
5eevK-5w1jA:
undetectable
5eevJ-5w1jA:
8.72
5eevK-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5eevA-5w1jA:
undetectable
5eevK-5w1jA:
undetectable
5eevA-5w1jA:
8.72
5eevK-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5eevN-5w1jA:
undetectable
5eevO-5w1jA:
undetectable
5eevN-5w1jA:
8.72
5eevO-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.21A 5eevP-5w1jA:
undetectable
5eevQ-5w1jA:
undetectable
5eevP-5w1jA:
8.72
5eevQ-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5eevR-5w1jA:
undetectable
5eevS-5w1jA:
undetectable
5eevR-5w1jA:
8.72
5eevS-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.20A 5eevS-5w1jA:
undetectable
5eevT-5w1jA:
undetectable
5eevS-5w1jA:
8.72
5eevT-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5eevT-5w1jA:
undetectable
5eevU-5w1jA:
undetectable
5eevT-5w1jA:
8.72
5eevU-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5eevU-5w1jA:
undetectable
5eevV-5w1jA:
undetectable
5eevU-5w1jA:
8.72
5eevV-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5eewB-5w1jA:
undetectable
5eewC-5w1jA:
undetectable
5eewB-5w1jA:
8.72
5eewC-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5eewE-5w1jA:
undetectable
5eewF-5w1jA:
undetectable
5eewE-5w1jA:
8.72
5eewF-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5eewG-5w1jA:
undetectable
5eewH-5w1jA:
undetectable
5eewG-5w1jA:
8.72
5eewH-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.25A 5eewH-5w1jA:
undetectable
5eewI-5w1jA:
undetectable
5eewH-5w1jA:
8.72
5eewI-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.25A 5eewJ-5w1jA:
undetectable
5eewK-5w1jA:
undetectable
5eewJ-5w1jA:
8.72
5eewK-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5eewA-5w1jA:
undetectable
5eewK-5w1jA:
undetectable
5eewA-5w1jA:
8.72
5eewK-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5eewN-5w1jA:
undetectable
5eewO-5w1jA:
undetectable
5eewN-5w1jA:
8.72
5eewO-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.21A 5eewP-5w1jA:
undetectable
5eewQ-5w1jA:
undetectable
5eewP-5w1jA:
8.72
5eewQ-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5eewR-5w1jA:
undetectable
5eewS-5w1jA:
undetectable
5eewR-5w1jA:
8.72
5eewS-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.20A 5eewS-5w1jA:
undetectable
5eewT-5w1jA:
undetectable
5eewS-5w1jA:
8.72
5eewT-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5eewT-5w1jA:
undetectable
5eewU-5w1jA:
undetectable
5eewT-5w1jA:
8.72
5eewU-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5eewU-5w1jA:
undetectable
5eewV-5w1jA:
undetectable
5eewU-5w1jA:
8.72
5eewV-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5eexB-5w1jA:
undetectable
5eexC-5w1jA:
undetectable
5eexB-5w1jA:
8.72
5eexC-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5eexE-5w1jA:
undetectable
5eexF-5w1jA:
undetectable
5eexE-5w1jA:
8.72
5eexF-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5eexG-5w1jA:
undetectable
5eexH-5w1jA:
undetectable
5eexG-5w1jA:
8.72
5eexH-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.25A 5eexH-5w1jA:
undetectable
5eexI-5w1jA:
undetectable
5eexH-5w1jA:
8.72
5eexI-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 11 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5eexI-5w1jA:
undetectable
5eexJ-5w1jA:
undetectable
5eexI-5w1jA:
8.72
5eexJ-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.25A 5eexJ-5w1jA:
undetectable
5eexK-5w1jA:
undetectable
5eexJ-5w1jA:
8.72
5eexK-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5eexA-5w1jA:
undetectable
5eexK-5w1jA:
undetectable
5eexA-5w1jA:
8.72
5eexK-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5eexN-5w1jA:
undetectable
5eexO-5w1jA:
undetectable
5eexN-5w1jA:
8.72
5eexO-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.21A 5eexP-5w1jA:
undetectable
5eexQ-5w1jA:
undetectable
5eexP-5w1jA:
8.72
5eexQ-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.21A 5eexQ-5w1jA:
undetectable
5eexR-5w1jA:
undetectable
5eexQ-5w1jA:
8.72
5eexR-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5eexR-5w1jA:
undetectable
5eexS-5w1jA:
undetectable
5eexR-5w1jA:
8.72
5eexS-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.20A 5eexS-5w1jA:
undetectable
5eexT-5w1jA:
undetectable
5eexS-5w1jA:
8.72
5eexT-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5eexT-5w1jA:
undetectable
5eexU-5w1jA:
undetectable
5eexT-5w1jA:
8.72
5eexU-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5eexU-5w1jA:
undetectable
5eexV-5w1jA:
undetectable
5eexU-5w1jA:
8.72
5eexV-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5eeyB-5w1jA:
undetectable
5eeyC-5w1jA:
undetectable
5eeyB-5w1jA:
8.72
5eeyC-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5eeyE-5w1jA:
undetectable
5eeyF-5w1jA:
undetectable
5eeyE-5w1jA:
8.72
5eeyF-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5eeyG-5w1jA:
undetectable
5eeyH-5w1jA:
undetectable
5eeyG-5w1jA:
8.72
5eeyH-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.25A 5eeyH-5w1jA:
undetectable
5eeyI-5w1jA:
undetectable
5eeyH-5w1jA:
8.72
5eeyI-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 11 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5eeyI-5w1jA:
undetectable
5eeyJ-5w1jA:
undetectable
5eeyI-5w1jA:
8.72
5eeyJ-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.25A 5eeyJ-5w1jA:
undetectable
5eeyK-5w1jA:
undetectable
5eeyJ-5w1jA:
8.72
5eeyK-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5eeyA-5w1jA:
undetectable
5eeyK-5w1jA:
undetectable
5eeyA-5w1jA:
8.72
5eeyK-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5eeyN-5w1jA:
undetectable
5eeyO-5w1jA:
undetectable
5eeyN-5w1jA:
8.72
5eeyO-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.21A 5eeyP-5w1jA:
undetectable
5eeyQ-5w1jA:
undetectable
5eeyP-5w1jA:
8.72
5eeyQ-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.21A 5eeyQ-5w1jA:
undetectable
5eeyR-5w1jA:
undetectable
5eeyQ-5w1jA:
8.72
5eeyR-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5eeyR-5w1jA:
undetectable
5eeyS-5w1jA:
undetectable
5eeyR-5w1jA:
8.72
5eeyS-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.20A 5eeyS-5w1jA:
undetectable
5eeyT-5w1jA:
undetectable
5eeyS-5w1jA:
8.72
5eeyT-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5eeyT-5w1jA:
undetectable
5eeyU-5w1jA:
undetectable
5eeyT-5w1jA:
8.72
5eeyU-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.18A 5eeyU-5w1jA:
undetectable
5eeyV-5w1jA:
undetectable
5eeyU-5w1jA:
8.72
5eeyV-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5eezB-5w1jA:
undetectable
5eezC-5w1jA:
undetectable
5eezB-5w1jA:
8.72
5eezC-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5eezE-5w1jA:
undetectable
5eezF-5w1jA:
undetectable
5eezE-5w1jA:
8.72
5eezF-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5eezG-5w1jA:
undetectable
5eezH-5w1jA:
undetectable
5eezG-5w1jA:
8.72
5eezH-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.25A 5eezH-5w1jA:
undetectable
5eezI-5w1jA:
undetectable
5eezH-5w1jA:
8.72
5eezI-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 11 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5eezI-5w1jA:
undetectable
5eezJ-5w1jA:
undetectable
5eezI-5w1jA:
8.72
5eezJ-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.25A 5eezJ-5w1jA:
undetectable
5eezK-5w1jA:
undetectable
5eezJ-5w1jA:
8.72
5eezK-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5eezA-5w1jA:
undetectable
5eezK-5w1jA:
undetectable
5eezA-5w1jA:
8.72
5eezK-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5eezN-5w1jA:
undetectable
5eezO-5w1jA:
undetectable
5eezN-5w1jA:
8.72
5eezO-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.21A 5eezP-5w1jA:
undetectable
5eezQ-5w1jA:
undetectable
5eezP-5w1jA:
8.72
5eezQ-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.21A 5eezQ-5w1jA:
undetectable
5eezR-5w1jA:
undetectable
5eezQ-5w1jA:
8.72
5eezR-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5eezR-5w1jA:
undetectable
5eezS-5w1jA:
undetectable
5eezR-5w1jA:
8.72
5eezS-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.20A 5eezS-5w1jA:
undetectable
5eezT-5w1jA:
undetectable
5eezS-5w1jA:
8.72
5eezT-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5eezT-5w1jA:
undetectable
5eezU-5w1jA:
undetectable
5eezT-5w1jA:
8.72
5eezU-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5eezU-5w1jA:
undetectable
5eezV-5w1jA:
undetectable
5eezU-5w1jA:
8.72
5eezV-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5ef0B-5w1jA:
undetectable
5ef0C-5w1jA:
undetectable
5ef0B-5w1jA:
8.72
5ef0C-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5ef0E-5w1jA:
undetectable
5ef0F-5w1jA:
undetectable
5ef0E-5w1jA:
8.72
5ef0F-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5ef0G-5w1jA:
undetectable
5ef0H-5w1jA:
undetectable
5ef0G-5w1jA:
8.72
5ef0H-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.25A 5ef0H-5w1jA:
undetectable
5ef0I-5w1jA:
undetectable
5ef0H-5w1jA:
8.72
5ef0I-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 11 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5ef0I-5w1jA:
undetectable
5ef0J-5w1jA:
undetectable
5ef0I-5w1jA:
8.72
5ef0J-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.25A 5ef0J-5w1jA:
undetectable
5ef0K-5w1jA:
undetectable
5ef0J-5w1jA:
8.72
5ef0K-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5ef0A-5w1jA:
undetectable
5ef0K-5w1jA:
undetectable
5ef0A-5w1jA:
8.72
5ef0K-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5ef0N-5w1jA:
undetectable
5ef0O-5w1jA:
undetectable
5ef0N-5w1jA:
8.72
5ef0O-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.21A 5ef0P-5w1jA:
undetectable
5ef0Q-5w1jA:
undetectable
5ef0P-5w1jA:
8.72
5ef0Q-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.21A 5ef0Q-5w1jA:
undetectable
5ef0R-5w1jA:
undetectable
5ef0Q-5w1jA:
8.72
5ef0R-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5ef0R-5w1jA:
undetectable
5ef0S-5w1jA:
undetectable
5ef0R-5w1jA:
8.72
5ef0S-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.20A 5ef0S-5w1jA:
undetectable
5ef0T-5w1jA:
undetectable
5ef0S-5w1jA:
8.72
5ef0T-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5ef0T-5w1jA:
undetectable
5ef0U-5w1jA:
undetectable
5ef0T-5w1jA:
8.72
5ef0U-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5ef0U-5w1jA:
undetectable
5ef0V-5w1jA:
undetectable
5ef0U-5w1jA:
8.72
5ef0V-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5ef1B-5w1jA:
undetectable
5ef1C-5w1jA:
undetectable
5ef1B-5w1jA:
8.72
5ef1C-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5ef1E-5w1jA:
undetectable
5ef1F-5w1jA:
undetectable
5ef1E-5w1jA:
8.72
5ef1F-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5ef1G-5w1jA:
undetectable
5ef1H-5w1jA:
undetectable
5ef1G-5w1jA:
8.72
5ef1H-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.25A 5ef1H-5w1jA:
undetectable
5ef1I-5w1jA:
undetectable
5ef1H-5w1jA:
8.72
5ef1I-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 11 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5ef1I-5w1jA:
undetectable
5ef1J-5w1jA:
undetectable
5ef1I-5w1jA:
8.72
5ef1J-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.25A 5ef1J-5w1jA:
undetectable
5ef1K-5w1jA:
undetectable
5ef1J-5w1jA:
8.72
5ef1K-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5ef1A-5w1jA:
undetectable
5ef1K-5w1jA:
undetectable
5ef1A-5w1jA:
8.72
5ef1K-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5ef1N-5w1jA:
undetectable
5ef1O-5w1jA:
undetectable
5ef1N-5w1jA:
8.72
5ef1O-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.21A 5ef1P-5w1jA:
undetectable
5ef1Q-5w1jA:
undetectable
5ef1P-5w1jA:
8.72
5ef1Q-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.21A 5ef1Q-5w1jA:
undetectable
5ef1R-5w1jA:
undetectable
5ef1Q-5w1jA:
8.72
5ef1R-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5ef1R-5w1jA:
undetectable
5ef1S-5w1jA:
undetectable
5ef1R-5w1jA:
8.72
5ef1S-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.20A 5ef1S-5w1jA:
undetectable
5ef1T-5w1jA:
undetectable
5ef1S-5w1jA:
8.72
5ef1T-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5ef1T-5w1jA:
undetectable
5ef1U-5w1jA:
undetectable
5ef1T-5w1jA:
8.72
5ef1U-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5ef1U-5w1jA:
undetectable
5ef1V-5w1jA:
undetectable
5ef1U-5w1jA:
8.72
5ef1V-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5ef2B-5w1jA:
undetectable
5ef2C-5w1jA:
undetectable
5ef2B-5w1jA:
8.72
5ef2C-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5ef2E-5w1jA:
undetectable
5ef2F-5w1jA:
undetectable
5ef2E-5w1jA:
8.72
5ef2F-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5ef2G-5w1jA:
undetectable
5ef2H-5w1jA:
undetectable
5ef2G-5w1jA:
8.72
5ef2H-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.25A 5ef2H-5w1jA:
undetectable
5ef2I-5w1jA:
undetectable
5ef2H-5w1jA:
8.72
5ef2I-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 11 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5ef2I-5w1jA:
undetectable
5ef2J-5w1jA:
undetectable
5ef2I-5w1jA:
8.72
5ef2J-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.25A 5ef2J-5w1jA:
undetectable
5ef2K-5w1jA:
undetectable
5ef2J-5w1jA:
8.72
5ef2K-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5ef2A-5w1jA:
undetectable
5ef2K-5w1jA:
undetectable
5ef2A-5w1jA:
8.72
5ef2K-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5ef2N-5w1jA:
undetectable
5ef2O-5w1jA:
undetectable
5ef2N-5w1jA:
8.72
5ef2O-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.21A 5ef2P-5w1jA:
undetectable
5ef2Q-5w1jA:
undetectable
5ef2P-5w1jA:
8.72
5ef2Q-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.21A 5ef2Q-5w1jA:
undetectable
5ef2R-5w1jA:
undetectable
5ef2Q-5w1jA:
8.72
5ef2R-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5ef2R-5w1jA:
undetectable
5ef2S-5w1jA:
undetectable
5ef2R-5w1jA:
8.72
5ef2S-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.20A 5ef2S-5w1jA:
undetectable
5ef2T-5w1jA:
undetectable
5ef2S-5w1jA:
8.72
5ef2T-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5ef2T-5w1jA:
undetectable
5ef2U-5w1jA:
undetectable
5ef2T-5w1jA:
8.72
5ef2U-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5ef2U-5w1jA:
undetectable
5ef2V-5w1jA:
undetectable
5ef2U-5w1jA:
8.72
5ef2V-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.22A 5ef3B-5w1jA:
undetectable
5ef3C-5w1jA:
undetectable
5ef3B-5w1jA:
8.72
5ef3C-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5ef3E-5w1jA:
undetectable
5ef3F-5w1jA:
undetectable
5ef3E-5w1jA:
8.72
5ef3F-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5ef3G-5w1jA:
undetectable
5ef3H-5w1jA:
undetectable
5ef3G-5w1jA:
8.72
5ef3H-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.25A 5ef3H-5w1jA:
undetectable
5ef3I-5w1jA:
undetectable
5ef3H-5w1jA:
8.72
5ef3I-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 11 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.23A 5ef3I-5w1jA:
undetectable
5ef3J-5w1jA:
undetectable
5ef3I-5w1jA:
8.72
5ef3J-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.25A 5ef3J-5w1jA:
undetectable
5ef3K-5w1jA:
undetectable
5ef3J-5w1jA:
8.72
5ef3K-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5ef3A-5w1jA:
undetectable
5ef3K-5w1jA:
undetectable
5ef3A-5w1jA:
8.72
5ef3K-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5ef3N-5w1jA:
undetectable
5ef3O-5w1jA:
undetectable
5ef3N-5w1jA:
8.72
5ef3O-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.20A 5ef3P-5w1jA:
undetectable
5ef3Q-5w1jA:
undetectable
5ef3P-5w1jA:
8.72
5ef3Q-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 9 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.21A 5ef3Q-5w1jA:
undetectable
5ef3R-5w1jA:
undetectable
5ef3Q-5w1jA:
8.72
5ef3R-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5ef3R-5w1jA:
undetectable
5ef3S-5w1jA:
undetectable
5ef3R-5w1jA:
8.72
5ef3S-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.20A 5ef3S-5w1jA:
undetectable
5ef3T-5w1jA:
undetectable
5ef3S-5w1jA:
8.72
5ef3T-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.24A 5ef3T-5w1jA:
undetectable
5ef3U-5w1jA:
undetectable
5ef3T-5w1jA:
8.72
5ef3U-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 10 GLY A 568
HIS A 570
THR A 579
THR A 578
ILE A 567
None
1.19A 5ef3U-5w1jA:
undetectable
5ef3V-5w1jA:
undetectable
5ef3U-5w1jA:
8.72
5ef3V-5w1jA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
4 / 8 VAL A 141
LEU A 137
TYR A 223
GLY A 117
FAD  A 601 ( 3.8A)
None
None
FAD  A 601 (-4.4A)
0.66A 5f1aA-5w1jA:
undetectable
5f1aA-5w1jA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
4 / 7 VAL A 141
LEU A 137
TYR A 223
GLY A 117
FAD  A 601 ( 3.8A)
None
None
FAD  A 601 (-4.4A)
0.69A 5f1aB-5w1jA:
undetectable
5f1aB-5w1jA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KF8_A_GCSA404_1
(PREDICTED
ACETYLTRANSFERASE)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
4 / 8 ARG A 260
GLY A 116
ASP A 139
TRP A 150
None
FAD  A 601 (-3.1A)
FAD  A 601 (-3.0A)
None
1.16A 5kf8A-5w1jA:
undetectable
5kf8A-5w1jA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
4 / 8 ARG A 260
GLY A 116
ASP A 139
TRP A 150
None
FAD  A 601 (-3.1A)
FAD  A 601 (-3.0A)
None
1.14A 5kgpA-5w1jA:
undetectable
5kgpA-5w1jA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
4 / 8 ARG A 260
GLY A 116
ASP A 139
TRP A 150
None
FAD  A 601 (-3.1A)
FAD  A 601 (-3.0A)
None
1.12A 5kgpB-5w1jA:
undetectable
5kgpB-5w1jA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKL_B_SAMB8009_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN,HISTONE H3.1
PEPTIDE,ZINC FINGER
DOMAIN-CONTAINING
PROTEIN)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 12 CYH A 310
GLY A 309
ASN A 285
HIS A 284
LEU A 282
None
1.47A 5kklB-5w1jA:
undetectable
5kklB-5w1jA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND2_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
5 / 12 VAL A 416
ASP A 417
ALA A 429
SER A 434
LEU A 451
None
1.27A 5nd2B-5w1jA:
undetectable
5nd2B-5w1jA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus)
4 / 5 ASP A 111
ILE A  43
ASN A  13
TYR A 456
None
1.04A 6a93B-5w1jA:
undetectable
6a93B-5w1jA:
21.37