SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5w1m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 5w1m PRE-GLYCOPROTEIN
POLYPROTEIN GP
COMPLEX
(Machupo
mammarenavirus) 		4 / 5 TYR Q 100
THR Q 107
PHE Q 108
LEU Q  91
 None
 1.37A 3qelC-5w1mQ:
undetectable		 3qelC-5w1mQ:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM2_B_TOPB202_1
(DIHYDROFOLATE
REDUCTASE)		 5w1m PRE-GLYCOPROTEIN
POLYPROTEIN GP
COMPLEX
(Machupo
mammarenavirus) 		5 / 12 ILE Q 217
ILE Q 192
PHE Q 148
LEU Q  91
ILE Q 110
 None
 1.10A 4km2B-5w1mQ:
undetectable		 4km2B-5w1mQ:
14.53