SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5w2b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_2
(ESTROGEN RECEPTOR)
5w2b NUCLEOPROTEIN
(Reston
ebolavirus)
4 / 4 LEU A 700
THR A 701
ILE A 734
HIS A 738
None
1.07A 2jfaB-5w2bA:
undetectable
2jfaB-5w2bA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNU_A_BEZA319_0
(SHKAI2IB)
5w2b NUCLEOPROTEIN
(Reston
ebolavirus)
4 / 5 GLN A 736
HIS A 737
ILE A 715
ILE A 713
None
1.11A 5dnuA-5w2bA:
undetectable
5dnuA-5w2bA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNV_A_BEZA304_0
(SHKAI2IB)
5w2b NUCLEOPROTEIN
(Reston
ebolavirus)
4 / 5 GLN A 736
HIS A 737
ILE A 715
ILE A 713
None
1.14A 5dnvA-5w2bA:
undetectable
5dnvA-5w2bA:
undetectable