SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5w35'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A8U_A_BEZA295_0 (CHLOROPEROXIDASE T)	5w35	DNA PRIMASE (Mycobacterium tuberculosis)	5 / 10	GLY A 158 PHE A 157 LEU A 144 PHE A 249 LEU A 204	None	1.39A	1a8uA-5w35A: undetectable	1a8uA-5w35A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A8U_B_BEZB294_0 (CHLOROPEROXIDASE T)	5w35	DNA PRIMASE (Mycobacterium tuberculosis)	5 / 10	GLY A 158 PHE A 157 LEU A 144 PHE A 249 LEU A 204	None	1.38A	1a8uB-5w35A: undetectable	1a8uB-5w35A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E7B_B_HLTB4003_1 (SERUM ALBUMIN)	5w35	DNA PRIMASE (Mycobacterium tuberculosis)	4 / 6	VAL A 406 GLY A 407 ALA A 419 LEU A 422	None	0.77A	1e7bB-5w35A: undetectable	1e7bB-5w35A: 8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1H9Z_A_RWFA3001_1 (SERUM ALBUMIN)	5w35	DNA PRIMASE (Mycobacterium tuberculosis)	5 / 11	ALA A 131 LEU A 132 ARG A 141 LEU A 223 ALA A 138	None	1.05A	1h9zA-5w35A: undetectable	1h9zA-5w35A: 8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MX8_A_RTLA135_0 (CELLULAR RETINOL-BINDING PROTEIN I, HOLO)	5w35	DNA PRIMASE (Mycobacterium tuberculosis)	5 / 12	PHE A 200 LEU A 205 LEU A 188 THR A 239 ILE A 208	None	1.17A	1mx8A-5w35A: undetectable	1mx8A-5w35A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WYG_A_SALA4005_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	5w35	DNA PRIMASE (Mycobacterium tuberculosis)	5 / 10	LEU A 169 SER A 189 PHE A 178 ALA A 123 ALA A 120	None	1.34A	1wygA-5w35A: undetectable	1wygA-5w35A: 6.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Z0Y_B_SAMB400_0 (PUTATIVE UNCHARACTERIZED PROTEIN TTHA0657)	5w35	DNA PRIMASE (Mycobacterium tuberculosis)	5 / 9	ALA A 186 GLY A 112 LEU A 188 LEU A 173 ALA A 120	None	0.92A	2z0yB-5w35A: undetectable	2z0yB-5w35A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Z0Y_B_SAMB400_0 (PUTATIVE UNCHARACTERIZED PROTEIN TTHA0657)	5w35	DNA PRIMASE (Mycobacterium tuberculosis)	5 / 9	ALA A 186 GLY A 112 LEU A 188 LEU A 173 ALA A 120	None	0.95A	2z0yB-5w35A: undetectable	2z0yB-5w35A: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1A8U_A_BEZA295_0","CHLOROPEROXIDASE T","5w35","DNA PRIMASE","Mycobacterium tuberculosis",5,"GLY A 158;PHE A 157;LEU A 144;PHE A 249;LEU A 204","None","1.39A","1a8uA-5w35A:undetectable","1a8uA-5w35A:undetectable"],["1A8U_B_BEZB294_0","CHLOROPEROXIDASE T","5w35","DNA PRIMASE","Mycobacterium tuberculosis",5,"GLY A 158;PHE A 157;LEU A 144;PHE A 249;LEU A 204","None","1.38A","1a8uB-5w35A:undetectable","1a8uB-5w35A:undetectable"],["1E7B_B_HLTB4003_1","SERUM ALBUMIN","5w35","DNA PRIMASE","Mycobacterium tuberculosis",4,"VAL A 406;GLY A 407;ALA A 419;LEU A 422","None","0.77A","1e7bB-5w35A:undetectable","1e7bB-5w35A:8.72"],["1H9Z_A_RWFA3001_1","SERUM ALBUMIN","5w35","DNA PRIMASE","Mycobacterium tuberculosis",5,"ALA A 131;LEU A 132;ARG A 141;LEU A 223;ALA A 138","None","1.05A","1h9zA-5w35A:undetectable","1h9zA-5w35A:8.72"],["1MX8_A_RTLA135_0","CELLULAR RETINOL-BINDING PROTEIN I, HOLO","5w35","DNA PRIMASE","Mycobacterium tuberculosis",5,"PHE A 200;LEU A 205;LEU A 188;THR A 239;ILE A 208","None","1.17A","1mx8A-5w35A:undetectable","1mx8A-5w35A:undetectable"],["1WYG_A_SALA4005_1","XANTHINE DEHYDROGENASE\/OXIDASE","5w35","DNA PRIMASE","Mycobacterium tuberculosis",5,"LEU A 169;SER A 189;PHE A 178;ALA A 123;ALA A 120","None","1.34A","1wygA-5w35A:undetectable","1wygA-5w35A:6.23"],["2Z0Y_B_SAMB400_0","PUTATIVE UNCHARACTERIZED PROTEIN TTHA0657","5w35","DNA PRIMASE","Mycobacterium tuberculosis",5,"ALA A 186;GLY A 112;LEU A 188;LEU A 173;ALA A 120","None","0.92A","2z0yB-5w35A:undetectable","2z0yB-5w35A:undetectable"],["2Z0Y_B_SAMB400_0","PUTATIVE UNCHARACTERIZED PROTEIN TTHA0657","5w35","DNA PRIMASE","Mycobacterium tuberculosis",5,"ALA A 186;GLY A 112;LEU A 188;LEU A 173;ALA A 120","None","0.95A","2z0yB-5w35A:undetectable","2z0yB-5w35A:undetectable"]]