SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5w3j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_CCSA381_0
(ESTROGEN RECEPTOR)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		4 / 5 HIS B 190
ALA B 185
SER B 145
HIS B 137
 None
 1.15A 1errA-5w3jB:
undetectable
1errB-5w3jB:
undetectable		 1errA-5w3jB:
19.43
1errB-5w3jB:
19.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IA0_B_TXLB502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 VAL B  23
LEU B 215
ARG B 318
PRO B 358
GLY B 360
 TA1  B 502 (-3.9A)
None
None
None
TA1  B 502 (-3.6A)
 0.81A 1ia0B-5w3jB:
46.0		 1ia0B-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
THR B 274
PRO B 358
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
TA1  B 502 (-4.7A)
None
TA1  B 502 (-3.6A)
 0.78A 1jffB-5w3jB:
54.2		 1jffB-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL B  23
ASP B  26
GLU B  27
SER B 234
PRO B 358
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
TA1  B 502 ( 4.9A)
None
TA1  B 502 (-3.6A)
 0.93A 1jffB-5w3jB:
54.2		 1jffB-5w3jB:
75.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_2
(CARBONIC ANHYDRASE
II)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		4 / 4 HIS B 264
VAL B 258
THR B 166
LEU B 250
 None
 1.32A 1oq5A-5w3jB:
undetectable		 1oq5A-5w3jB:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_A_SAMA1401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 11 LEU B 139
GLY B 146
GLY B 144
ILE B 152
LEU B 418
 None
None
GDP  B 501 (-4.6A)
None
None
 1.09A 1p91A-5w3jB:
undetectable		 1p91A-5w3jB:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 GLY B 223
ASN B  65
SER B  63
GLY B  82
SER B  79
 None
 1.07A 1q8jB-5w3jB:
undetectable		 1q8jB-5w3jB:
23.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TUB_B_TXLB501_1
(TUBULIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 VAL B  23
LEU B 215
ARG B 318
PRO B 358
GLY B 360
 TA1  B 502 (-3.9A)
None
None
None
TA1  B 502 (-3.6A)
 0.81A 1tubB-5w3jB:
46.0		 1tubB-5w3jB:
77.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		3 / 3 PHE B 316
ARG B  46
ASN B 247
 None
 0.76A 1xzxX-5w3jB:
undetectable		 1xzxX-5w3jB:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 253
ALA B 254
ALA B 314
ASP B 249
PHE B 316
 None
 1.23A 2ejtA-5w3jB:
2.2		 2ejtA-5w3jB:
23.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
THR B 274
PRO B 358
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
TA1  B 502 (-4.7A)
None
TA1  B 502 (-3.6A)
 0.78A 2hxfB-5w3jB:
38.9		 2hxfB-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL B  23
ASP B  26
GLU B  27
SER B 234
PRO B 358
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
TA1  B 502 ( 4.9A)
None
TA1  B 502 (-3.6A)
 0.93A 2hxfB-5w3jB:
38.9		 2hxfB-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
THR B 274
PRO B 358
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
TA1  B 502 (-4.7A)
None
TA1  B 502 (-3.6A)
 0.78A 2hxhB-5w3jB:
38.9		 2hxhB-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL B  23
ASP B  26
GLU B  27
SER B 234
PRO B 358
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
TA1  B 502 ( 4.9A)
None
TA1  B 502 (-3.6A)
 0.93A 2hxhB-5w3jB:
38.9		 2hxhB-5w3jB:
75.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 GLY B  98
GLY B 148
GLY B 146
GLY B 104
THR B 149
ILE B 135
 GDP  B 501 (-4.4A)
None
None
None
None
None
 1.22A 2oxtB-5w3jB:
undetectable		 2oxtB-5w3jB:
18.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
THR B 274
PRO B 358
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
TA1  B 502 (-4.7A)
None
TA1  B 502 (-3.6A)
 0.78A 2p4nB-5w3jB:
54.2		 2p4nB-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL B  23
ASP B  26
GLU B  27
SER B 234
PRO B 358
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
TA1  B 502 ( 4.9A)
None
TA1  B 502 (-3.6A)
 0.94A 2p4nB-5w3jB:
54.2		 2p4nB-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
THR B 274
PRO B 358
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
TA1  B 502 (-4.7A)
None
TA1  B 502 (-3.6A)
 0.77A 2wbeB-5w3jB:
54.1		 2wbeB-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL B  23
ASP B  26
GLU B  27
SER B 234
PRO B 358
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
TA1  B 502 ( 4.9A)
None
TA1  B 502 (-3.6A)
 0.92A 2wbeB-5w3jB:
54.1		 2wbeB-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
THR B 274
PRO B 358
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
TA1  B 502 (-4.7A)
None
TA1  B 502 (-3.6A)
 0.77A 3dcoB-5w3jB:
54.1		 3dcoB-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL B  23
ASP B  26
GLU B  27
SER B 234
PRO B 358
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
TA1  B 502 ( 4.9A)
None
TA1  B 502 (-3.6A)
 0.93A 3dcoB-5w3jB:
54.1		 3dcoB-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
THR B 274
PRO B 358
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
TA1  B 502 (-4.7A)
None
TA1  B 502 (-3.6A)
 0.74A 3edlB-5w3jB:
54.1		 3edlB-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL B  23
ASP B  26
GLU B  27
SER B 234
PRO B 358
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
TA1  B 502 ( 4.9A)
None
TA1  B 502 (-3.6A)
 0.94A 3edlB-5w3jB:
54.1		 3edlB-5w3jB:
75.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_F_TOPF200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 10 ALA B 411
ASN B 184
LEU B 187
LEU B 395
PHE B 389
 None
 1.07A 3fl9F-5w3jB:
undetectable		 3fl9F-5w3jB:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_G_TOPG200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 ALA B 411
ASN B 184
LEU B 187
LEU B 395
PHE B 389
 None
 1.07A 3fl9G-5w3jB:
undetectable		 3fl9G-5w3jB:
16.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
THR B 274
PRO B 358
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
TA1  B 502 (-4.7A)
None
TA1  B 502 (-3.6A)
 0.78A 3iz0B-5w3jB:
54.1		 3iz0B-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL B  23
ASP B  26
GLU B  27
SER B 234
PRO B 358
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
TA1  B 502 ( 4.9A)
None
TA1  B 502 (-3.6A)
 0.94A 3iz0B-5w3jB:
54.1		 3iz0B-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 10 VAL B  23
ASP B  26
LEU B 228
THR B 274
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
TA1  B 502 (-4.7A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.03A 3j6gB-5w3jB:
56.6		 3j6gB-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 10 VAL B  23
ASP B  26
SER B 230
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.40A 3j6gB-5w3jB:
56.6		 3j6gB-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 10 VAL B  23
ASP B  26
SER B 234
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 ( 4.9A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.19A 3j6gB-5w3jB:
56.6		 3j6gB-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_D_TA1D502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 10 VAL B  23
ASP B  26
LEU B 228
THR B 274
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
TA1  B 502 (-4.7A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.03A 3j6gD-5w3jB:
56.6		 3j6gD-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_D_TA1D502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 10 VAL B  23
ASP B  26
SER B 230
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.40A 3j6gD-5w3jB:
56.6		 3j6gD-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_D_TA1D502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 10 VAL B  23
ASP B  26
SER B 234
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 ( 4.9A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.19A 3j6gD-5w3jB:
56.6		 3j6gD-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_F_TA1F502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 10 VAL B  23
ASP B  26
LEU B 228
THR B 274
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
TA1  B 502 (-4.7A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.04A 3j6gF-5w3jB:
56.6		 3j6gF-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_F_TA1F502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 10 VAL B  23
ASP B  26
SER B 230
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.41A 3j6gF-5w3jB:
56.6		 3j6gF-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_F_TA1F502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 10 VAL B  23
ASP B  26
SER B 234
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 ( 4.9A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.19A 3j6gF-5w3jB:
56.6		 3j6gF-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_H_TA1H502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 10 VAL B  23
ASP B  26
LEU B 228
THR B 274
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
TA1  B 502 (-4.7A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.02A 3j6gH-5w3jB:
56.7		 3j6gH-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_H_TA1H502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 10 VAL B  23
ASP B  26
SER B 230
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.40A 3j6gH-5w3jB:
56.7		 3j6gH-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_H_TA1H502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 10 VAL B  23
ASP B  26
SER B 234
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 ( 4.9A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.19A 3j6gH-5w3jB:
56.7		 3j6gH-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_J_TA1J502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 10 VAL B  23
ASP B  26
LEU B 228
THR B 274
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
TA1  B 502 (-4.7A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.03A 3j6gJ-5w3jB:
56.6		 3j6gJ-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_J_TA1J502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 10 VAL B  23
ASP B  26
SER B 230
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.40A 3j6gJ-5w3jB:
56.6		 3j6gJ-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_J_TA1J502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 10 VAL B  23
ASP B  26
SER B 234
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 ( 4.9A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.19A 3j6gJ-5w3jB:
56.6		 3j6gJ-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_L_TA1L502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 10 VAL B  23
ASP B  26
LEU B 228
THR B 274
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
TA1  B 502 (-4.7A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.03A 3j6gL-5w3jB:
56.6		 3j6gL-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_L_TA1L502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 10 VAL B  23
ASP B  26
SER B 230
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.40A 3j6gL-5w3jB:
56.6		 3j6gL-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_L_TA1L502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 10 VAL B  23
ASP B  26
SER B 234
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 ( 4.9A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.19A 3j6gL-5w3jB:
56.6		 3j6gL-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_N_TA1N502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 10 VAL B  23
ASP B  26
LEU B 228
THR B 274
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
TA1  B 502 (-4.7A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.03A 3j6gN-5w3jB:
56.6		 3j6gN-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_N_TA1N502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 10 VAL B  23
ASP B  26
SER B 230
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.40A 3j6gN-5w3jB:
56.6		 3j6gN-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_N_TA1N502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 10 VAL B  23
ASP B  26
SER B 234
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 ( 4.9A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.19A 3j6gN-5w3jB:
56.6		 3j6gN-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_P_TA1P502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 10 VAL B  23
ASP B  26
LEU B 228
THR B 274
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
TA1  B 502 (-4.7A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.03A 3j6gP-5w3jB:
56.6		 3j6gP-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_P_TA1P502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 10 VAL B  23
ASP B  26
SER B 230
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.41A 3j6gP-5w3jB:
56.6		 3j6gP-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_P_TA1P502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 10 VAL B  23
ASP B  26
SER B 234
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 ( 4.9A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.19A 3j6gP-5w3jB:
56.6		 3j6gP-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_R_TA1R502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 10 VAL B  23
ASP B  26
LEU B 228
THR B 274
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
TA1  B 502 (-4.7A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.03A 3j6gR-5w3jB:
56.6		 3j6gR-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_R_TA1R502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 10 VAL B  23
ASP B  26
SER B 230
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.40A 3j6gR-5w3jB:
56.6		 3j6gR-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6G_R_TA1R502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 10 VAL B  23
ASP B  26
SER B 234
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 ( 4.9A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.19A 3j6gR-5w3jB:
56.6		 3j6gR-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 ASP B  26
LEU B 215
THR B 274
PRO B 358
GLY B 360
LEU B 361
 TA1  B 502 (-4.1A)
None
TA1  B 502 (-4.7A)
None
TA1  B 502 (-3.6A)
TA1  B 502 (-3.7A)
 1.24A 3j6pB-5w3jB:
53.4		 3j6pB-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 ASP B  26
SER B 234
PRO B 358
GLY B 360
LEU B 361
 TA1  B 502 (-4.1A)
TA1  B 502 ( 4.9A)
None
TA1  B 502 (-3.6A)
TA1  B 502 (-3.7A)
 1.28A 3j6pB-5w3jB:
53.4		 3j6pB-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
THR B 274
PRO B 358
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
TA1  B 502 (-4.7A)
None
TA1  B 502 (-3.6A)
 0.79A 3j6pB-5w3jB:
53.4		 3j6pB-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL B  23
ASP B  26
GLU B  27
SER B 234
PRO B 358
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
TA1  B 502 ( 4.9A)
None
TA1  B 502 (-3.6A)
 0.92A 3j6pB-5w3jB:
53.4		 3j6pB-5w3jB:
75.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 GLU B 108
GLY B  98
VAL B 116
GLY B  93
SER B  95
 None
GDP  B 501 (-4.4A)
None
None
None
 1.06A 3k13B-5w3jB:
2.4		 3k13B-5w3jB:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 GLU B 108
GLY B  98
VAL B 116
GLY B  93
SER B  95
 None
GDP  B 501 (-4.4A)
None
None
None
 1.05A 3k13C-5w3jB:
2.4		 3k13C-5w3jB:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZMD_A_SALA201_1
(PUTATIVE
TRANSCRIPTIONAL
REGULATOR)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		4 / 8 TRP B 101
MET B 403
TYR B 398
GLU B 401
 None
 1.39A 3zmdA-5w3jB:
undetectable
3zmdB-5w3jB:
undetectable		 3zmdA-5w3jB:
17.67
3zmdB-5w3jB:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		4 / 8 GLY B 144
GLY B 104
GLU B 111
LEU B 112
 GDP  B 501 (-4.6A)
None
None
None
 0.69A 4mwzB-5w3jB:
undetectable		 4mwzB-5w3jB:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 ALA B  97
GLY B 109
ILE B 135
THR B 166
GLY B 144
 None
None
None
None
GDP  B 501 (-4.6A)
 1.02A 4n48B-5w3jB:
4.1		 4n48B-5w3jB:
22.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O2B_B_LOCB503_2
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 253
ASN B 256
THR B 312
ALA B 314
ILE B 368
 None
 0.81A 4o2bB-5w3jB:
55.1		 4o2bB-5w3jB:
75.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 253
ASN B 256
THR B 312
ALA B 314
ILE B 368
 None
 0.75A 4x1iD-5w3jB:
53.3		 4x1iD-5w3jB:
75.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 253
ASN B 256
THR B 312
ALA B 314
ILE B 368
 None
 0.84A 4x1yB-5w3jB:
53.8		 4x1yB-5w3jB:
75.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 253
ASN B 256
THR B 312
ALA B 314
ILE B 368
 None
 0.72A 4x1yD-5w3jB:
53.6		 4x1yD-5w3jB:
75.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X20_B_LOCB502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 253
ASN B 256
THR B 312
ALA B 314
ILE B 368
 None
 0.86A 4x20B-5w3jB:
53.5		 4x20B-5w3jB:
75.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 11 LEU B 253
ASN B 256
THR B 312
ALA B 314
ILE B 368
 None
 0.87A 4x20D-5w3jB:
53.2		 4x20D-5w3jB:
75.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 10 GLY B  17
ASN B  65
SER B   8
ILE B  24
PRO B  61
 None
 1.12A 4xj7C-5w3jB:
2.3
4xj7D-5w3jB:
undetectable		 4xj7C-5w3jB:
19.29
4xj7D-5w3jB:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		4 / 6 ARG B  77
ASP B  74
VAL B  66
ASP B  67
 None
 1.06A 4xqeA-5w3jB:
4.3		 4xqeA-5w3jB:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		4 / 6 ARG B  77
ASP B  74
VAL B  66
ASP B  67
 None
 1.06A 4xqeB-5w3jB:
3.4		 4xqeB-5w3jB:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_A_AG2A505_1
(HOMOSPERMIDINE
SYNTHASE)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		4 / 8 ARG B  77
ASP B  74
VAL B  66
ASP B  67
 None
 1.06A 4xqgA-5w3jB:
4.1		 4xqgA-5w3jB:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		4 / 8 ARG B  77
ASP B  74
VAL B  66
ASP B  67
 None
 1.05A 4xqgB-5w3jB:
4.4		 4xqgB-5w3jB:
23.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
THR B 274
PRO B 358
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
TA1  B 502 (-4.7A)
None
 0.59A 5hnwB-5w3jB:
54.1		 5hnwB-5w3jB:
75.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 228
THR B 274
PRO B 358
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
TA1  B 502 (-4.7A)
None
 0.79A 5hnwB-5w3jB:
54.1		 5hnwB-5w3jB:
75.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 VAL B  23
ASP B  26
GLU B  27
SER B 234
PRO B 358
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
TA1  B 502 ( 4.9A)
None
 0.92A 5hnwB-5w3jB:
54.1		 5hnwB-5w3jB:
75.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HNX_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 228
THR B 274
PRO B 358
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
TA1  B 502 (-4.7A)
None
 0.89A 5hnxB-5w3jB:
54.1		 5hnxB-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HNX_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 VAL B  23
ASP B  26
GLU B  27
SER B 234
PRO B 358
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
TA1  B 502 ( 4.9A)
None
 0.93A 5hnxB-5w3jB:
54.1		 5hnxB-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
THR B 274
PRO B 358
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
TA1  B 502 (-4.7A)
None
 0.72A 5hnyB-5w3jB:
54.0		 5hnyB-5w3jB:
77.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 228
THR B 274
PRO B 358
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
TA1  B 502 (-4.7A)
None
 0.97A 5hnyB-5w3jB:
54.0		 5hnyB-5w3jB:
77.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 VAL B  23
ASP B  26
GLU B  27
SER B 234
PRO B 358
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
TA1  B 502 ( 4.9A)
None
 0.99A 5hnyB-5w3jB:
54.0		 5hnyB-5w3jB:
77.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HNZ_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
ASP B 224
THR B 274
PRO B 358
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
None
TA1  B 502 (-4.7A)
None
 0.52A 5hnzB-5w3jB:
54.2		 5hnzB-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HNZ_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 VAL B  23
ASP B  26
GLU B  27
SER B 234
PRO B 358
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
TA1  B 502 ( 4.9A)
None
 0.95A 5hnzB-5w3jB:
54.2		 5hnzB-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 253
ASN B 256
THR B 312
ALA B 314
ILE B 368
 None
 0.81A 5itzB-5w3jB:
53.4		 5itzB-5w3jB:
75.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		4 / 6 SER B  63
GLY B  13
ASN B  14
ILE B 135
 None
 1.04A 5j4nA-5w3jB:
undetectable		 5j4nA-5w3jB:
21.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M50_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 SER B 234
THR B 274
GLN B 279
ARG B 318
PRO B 358
GLY B 360
LEU B 361
 TA1  B 502 ( 4.9A)
TA1  B 502 (-4.7A)
TA1  B 502 ( 4.3A)
None
None
TA1  B 502 (-3.6A)
TA1  B 502 (-3.7A)
 1.31A 5m50B-5w3jB:
58.0		 5m50B-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M50_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
GLU B  27
THR B 274
GLN B 279
ARG B 318
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
TA1  B 502 (-4.7A)
TA1  B 502 ( 4.3A)
None
TA1  B 502 (-3.6A)
 1.05A 5m50B-5w3jB:
58.0		 5m50B-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M50_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
SER B 234
THR B 274
GLN B 279
ARG B 318
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 ( 4.9A)
TA1  B 502 (-4.7A)
TA1  B 502 ( 4.3A)
None
TA1  B 502 (-3.6A)
 1.09A 5m50B-5w3jB:
58.0		 5m50B-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M50_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
GLU B  27
THR B 274
GLN B 279
ARG B 318
PRO B 358
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-3.6A)
TA1  B 502 (-4.7A)
TA1  B 502 ( 4.3A)
None
None
TA1  B 502 (-3.6A)
 1.03A 5m50B-5w3jB:
58.0		 5m50B-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M50_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
SER B 234
THR B 274
GLN B 279
ARG B 318
PRO B 358
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 ( 4.9A)
TA1  B 502 (-4.7A)
TA1  B 502 ( 4.3A)
None
None
TA1  B 502 (-3.6A)
 1.10A 5m50B-5w3jB:
58.0		 5m50B-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M50_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 215
THR B 274
GLN B 279
GLY B 360
LEU B 361
 None
TA1  B 502 (-4.7A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.6A)
TA1  B 502 (-3.7A)
 1.02A 5m50E-5w3jB:
undetectable		 5m50E-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M50_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 SER B 234
THR B 274
GLN B 279
GLY B 360
LEU B 361
 TA1  B 502 ( 4.9A)
TA1  B 502 (-4.7A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.6A)
TA1  B 502 (-3.7A)
 1.33A 5m50E-5w3jB:
undetectable		 5m50E-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M50_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		8 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
THR B 274
GLN B 279
ARG B 318
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
TA1  B 502 (-4.7A)
TA1  B 502 ( 4.3A)
None
TA1  B 502 (-3.6A)
 1.01A 5m50E-5w3jB:
undetectable		 5m50E-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M50_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
SER B 234
THR B 274
GLN B 279
ARG B 318
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 ( 4.9A)
TA1  B 502 (-4.7A)
TA1  B 502 ( 4.3A)
None
TA1  B 502 (-3.6A)
 1.03A 5m50E-5w3jB:
undetectable		 5m50E-5w3jB:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 VAL B  23
ASP B  26
GLU B  27
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.09A 5m54B-5w3jB:
58.4		 5m54B-5w3jB:
77.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 VAL B  23
ASP B  26
SER B 230
THR B 274
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
TA1  B 502 (-4.7A)
TA1  B 502 (-3.7A)
 1.42A 5m54B-5w3jB:
58.4		 5m54B-5w3jB:
77.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL B  23
ASP B  26
SER B 234
THR B 274
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 ( 4.9A)
TA1  B 502 (-4.7A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.10A 5m54B-5w3jB:
58.4		 5m54B-5w3jB:
77.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M54_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
SER B 230
THR B 274
GLN B 279
GLY B 360
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
TA1  B 502 (-4.7A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.6A)
TA1  B 502 (-3.7A)
 1.49A 5m54E-5w3jB:
58.4		 5m54E-5w3jB:
77.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M54_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
SER B 234
THR B 274
GLN B 279
GLY B 360
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 ( 4.9A)
TA1  B 502 (-4.7A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.6A)
TA1  B 502 (-3.7A)
 1.20A 5m54E-5w3jB:
58.4		 5m54E-5w3jB:
77.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M5C_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 GLU B  27
LEU B 228
THR B 274
GLN B 279
GLY B 360
LEU B 361
 TA1  B 502 (-3.6A)
None
TA1  B 502 (-4.7A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.6A)
TA1  B 502 (-3.7A)
 1.18A 5m5cB-5w3jB:
58.5		 5m5cB-5w3jB:
77.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M5C_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 228
THR B 274
GLN B 279
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
TA1  B 502 (-4.7A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.6A)
 1.10A 5m5cB-5w3jB:
58.5		 5m5cB-5w3jB:
77.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M5C_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL B  23
ASP B  26
SER B 234
THR B 274
GLN B 279
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 ( 4.9A)
TA1  B 502 (-4.7A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.6A)
 0.95A 5m5cB-5w3jB:
58.5		 5m5cB-5w3jB:
77.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M5C_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 10 GLU B  27
LEU B 228
THR B 274
GLY B 360
LEU B 361
 TA1  B 502 (-3.6A)
None
TA1  B 502 (-4.7A)
TA1  B 502 (-3.6A)
TA1  B 502 (-3.7A)
 1.16A 5m5cE-5w3jB:
58.5		 5m5cE-5w3jB:
77.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M5C_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 10 VAL B  23
ASP B  26
GLU B  27
LEU B 228
THR B 274
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
TA1  B 502 (-4.7A)
TA1  B 502 (-3.6A)
 1.17A 5m5cE-5w3jB:
58.5		 5m5cE-5w3jB:
77.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M5C_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 10 VAL B  23
ASP B  26
SER B 234
THR B 274
GLY B 360
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 ( 4.9A)
TA1  B 502 (-4.7A)
TA1  B 502 (-3.6A)
 0.97A 5m5cE-5w3jB:
58.5		 5m5cE-5w3jB:
77.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MIO_B_LOCB502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 253
ASN B 256
THR B 312
ALA B 314
ILE B 368
 None
 0.80A 5mioB-5w3jB:
54.7		 5mioB-5w3jB:
75.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MM4_B_TA1B501_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 10 VAL B  23
LEU B 217
SER B 234
THR B 274
PRO B 358
LEU B 361
 TA1  B 502 (-3.9A)
None
TA1  B 502 ( 4.9A)
TA1  B 502 (-4.7A)
None
TA1  B 502 (-3.7A)
 1.11A 5mm4B-5w3jB:
57.7		 5mm4B-5w3jB:
17.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ND2_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
ARG B 318
PRO B 358
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
None
None
TA1  B 502 (-3.7A)
 0.82A 5nd2B-5w3jB:
55.7		 5nd2B-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ND2_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
GLU B  27
SER B 234
ARG B 318
PRO B 358
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
TA1  B 502 ( 4.9A)
None
None
TA1  B 502 (-3.7A)
 0.94A 5nd2B-5w3jB:
55.7		 5nd2B-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ND3_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
LEU B 228
THR B 274
ARG B 318
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
None
TA1  B 502 (-4.7A)
None
 1.19A 5nd3B-5w3jB:
56.2		 5nd3B-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ND3_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
SER B 234
ARG B 318
PRO B 358
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
TA1  B 502 ( 4.9A)
None
None
 1.17A 5nd3B-5w3jB:
56.2		 5nd3B-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ND3_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
THR B 274
ARG B 318
PRO B 358
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
TA1  B 502 (-4.7A)
None
None
 1.22A 5nd3B-5w3jB:
56.2		 5nd3B-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 228
ARG B 318
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
None
TA1  B 502 (-3.7A)
 1.11A 5nd4B-5w3jB:
56.0		 5nd4B-5w3jB:
77.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL B  23
ASP B  26
LEU B 228
ARG B 318
PRO B 358
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
None
None
TA1  B 502 (-3.7A)
 1.10A 5nd4B-5w3jB:
56.0		 5nd4B-5w3jB:
77.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL B  23
ASP B  26
SER B 234
ARG B 318
PRO B 358
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 ( 4.9A)
None
None
TA1  B 502 (-3.7A)
 0.95A 5nd4B-5w3jB:
56.0		 5nd4B-5w3jB:
77.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ND7_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
LEU B 228
ARG B 318
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
None
None
TA1  B 502 (-3.7A)
 1.12A 5nd7B-5w3jB:
55.9		 5nd7B-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ND7_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL B  23
ASP B  26
GLU B  27
SER B 234
ARG B 318
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
TA1  B 502 ( 4.9A)
None
TA1  B 502 (-3.7A)
 1.10A 5nd7B-5w3jB:
55.9		 5nd7B-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGC_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		8 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
THR B 274
PRO B 358
GLY B 360
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
TA1  B 502 (-4.7A)
None
TA1  B 502 (-3.6A)
TA1  B 502 (-3.7A)
 1.01A 5ogcB-5w3jB:
54.6		 5ogcB-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGC_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
GLU B  27
SER B 234
PRO B 358
GLY B 360
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
TA1  B 502 ( 4.9A)
None
TA1  B 502 (-3.6A)
TA1  B 502 (-3.7A)
 1.00A 5ogcB-5w3jB:
54.6		 5ogcB-5w3jB:
75.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SYE_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 GLU B  22
VAL B  23
ASP B 224
GLN B 279
ARG B 318
PRO B 358
GLY B 360
 TA1  B 502 ( 4.2A)
TA1  B 502 (-3.9A)
None
TA1  B 502 ( 4.3A)
None
None
TA1  B 502 (-3.6A)
 1.06A 5syeB-5w3jB:
59.3		 5syeB-5w3jB:
78.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SYE_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 GLU B  22
VAL B  23
LEU B 215
ASP B 224
ARG B 318
PRO B 358
GLY B 360
 TA1  B 502 ( 4.2A)
TA1  B 502 (-3.9A)
None
None
None
None
TA1  B 502 (-3.6A)
 0.85A 5syeB-5w3jB:
59.3		 5syeB-5w3jB:
78.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SYE_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 GLU B  22
VAL B  23
LEU B 215
SER B 234
ARG B 318
PRO B 358
GLY B 360
 TA1  B 502 ( 4.2A)
TA1  B 502 (-3.9A)
None
TA1  B 502 ( 4.9A)
None
None
TA1  B 502 (-3.6A)
 0.84A 5syeB-5w3jB:
59.3		 5syeB-5w3jB:
78.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SYE_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 VAL B  23
ASP B  26
LEU B 215
SER B 234
ARG B 318
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
TA1  B 502 ( 4.9A)
None
 0.98A 5syeB-5w3jB:
59.3		 5syeB-5w3jB:
78.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL B  23
ASP B  26
LEU B 215
ASP B 224
SER B 234
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
None
TA1  B 502 ( 4.9A)
TA1  B 502 (-3.7A)
 0.75A 5syfB-5w3jB:
60.1		 5syfB-5w3jB:
78.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL B  23
ASP B  26
LEU B 215
SER B 234
PRO B 358
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
TA1  B 502 ( 4.9A)
None
TA1  B 502 (-3.7A)
 0.74A 5syfB-5w3jB:
60.1		 5syfB-5w3jB:
78.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 GLU B 108
GLY B  98
VAL B 116
GLY B  93
SER B  95
 None
GDP  B 501 (-4.4A)
None
None
None
 1.17A 5vooA-5w3jB:
2.2		 5vooA-5w3jB:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_B_C2FB702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 GLU B 108
GLY B  98
VAL B 116
GLY B  93
SER B  95
 None
GDP  B 501 (-4.4A)
None
None
None
 1.16A 5vooB-5w3jB:
2.3		 5vooB-5w3jB:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 GLU B 108
GLY B  98
VAL B 116
GLY B  93
SER B  95
 None
GDP  B 501 (-4.4A)
None
None
None
 1.15A 5vooC-5w3jB:
2.3		 5vooC-5w3jB:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 GLU B 108
GLY B  98
VAL B 116
GLY B  93
SER B  95
 None
GDP  B 501 (-4.4A)
None
None
None
 1.18A 5vooD-5w3jB:
undetectable		 5vooD-5w3jB:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 GLU B 108
GLY B  98
VAL B 116
GLY B  93
SER B  95
 None
GDP  B 501 (-4.4A)
None
None
None
 1.14A 5vooE-5w3jB:
undetectable		 5vooE-5w3jB:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_F_C2FF3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 GLU B 108
GLY B  98
VAL B 116
GLY B  93
SER B  95
 None
GDP  B 501 (-4.4A)
None
None
None
 1.19A 5vooF-5w3jB:
2.1		 5vooF-5w3jB:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 GLU B 108
GLY B  98
VAL B 116
GLY B  93
SER B  95
 None
GDP  B 501 (-4.4A)
None
None
None
 1.17A 5vopB-5w3jB:
undetectable		 5vopB-5w3jB:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		4 / 7 THR B 312
LEU B 311
ILE B 374
THR B 372
 None
 0.90A 5zsfA-5w3jB:
undetectable
5zsfB-5w3jB:
undetectable		 5zsfA-5w3jB:
13.29
5zsfB-5w3jB:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL B  23
ASP B  26
LEU B 215
ASP B 224
HIS B 227
LEU B 228
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
None
TA1  B 502 (-4.3A)
None
 1.23A 6b0iB-5w3jB:
59.6		 6b0iB-5w3jB:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		8 / 12 VAL B  23
ASP B  26
LEU B 215
ASP B 224
LEU B 228
PRO B 358
GLY B 360
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
None
None
None
TA1  B 502 (-3.6A)
TA1  B 502 (-3.7A)
 0.73A 6b0iB-5w3jB:
59.6		 6b0iB-5w3jB:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
LEU B 215
SER B 234
PRO B 358
GLY B 360
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
TA1  B 502 ( 4.9A)
None
TA1  B 502 (-3.6A)
TA1  B 502 (-3.7A)
 0.72A 6b0iB-5w3jB:
59.6		 6b0iB-5w3jB:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		9 / 12 VAL B  23
ASP B  26
LEU B 215
ASP B 224
LEU B 228
THR B 274
PRO B 358
GLY B 360
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
None
None
TA1  B 502 (-4.7A)
None
TA1  B 502 (-3.6A)
TA1  B 502 (-3.7A)
 0.86A 6b0lB-5w3jB:
58.6		 6b0lB-5w3jB:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
LEU B 215
SER B 234
THR B 274
GLY B 360
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
TA1  B 502 ( 4.9A)
TA1  B 502 (-4.7A)
TA1  B 502 (-3.6A)
TA1  B 502 (-3.7A)
 0.93A 6b0lB-5w3jB:
58.6		 6b0lB-5w3jB:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		3 / 3 SER B 371
SER B 373
ALA B 296
 None
 0.69A 6dwnC-5w3jB:
undetectable		 6dwnC-5w3jB:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 VAL B  23
ASP B  26
GLU B  27
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.09A 6ew0B-5w3jB:
60.4		 6ew0B-5w3jB:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
LEU B 217
SER B 234
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
None
TA1  B 502 ( 4.9A)
TA1  B 502 (-3.7A)
 0.76A 6ew0B-5w3jB:
60.4		 6ew0B-5w3jB:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 VAL B  23
ASP B  26
GLU B  27
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.09A 6ew0D-5w3jB:
60.4		 6ew0D-5w3jB:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
LEU B 217
SER B 234
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
None
TA1  B 502 ( 4.9A)
TA1  B 502 (-3.7A)
 0.76A 6ew0D-5w3jB:
60.4		 6ew0D-5w3jB:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 VAL B  23
ASP B  26
GLU B  27
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.09A 6ew0F-5w3jB:
60.5		 6ew0F-5w3jB:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
ASP B 224
SER B 234
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
None
TA1  B 502 ( 4.9A)
TA1  B 502 (-3.7A)
 0.80A 6ew0F-5w3jB:
60.5		 6ew0F-5w3jB:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 273
SER B 234
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
TA1  B 502 ( 4.9A)
 1.24A 6ew0F-5w3jB:
60.5		 6ew0F-5w3jB:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 VAL B  23
ASP B  26
GLU B  27
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.10A 6ew0G-5w3jB:
60.4		 6ew0G-5w3jB:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
SER B 234
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
TA1  B 502 ( 4.9A)
TA1  B 502 (-3.7A)
 0.80A 6ew0G-5w3jB:
60.4		 6ew0G-5w3jB:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 VAL B  23
ASP B  26
GLU B  27
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.10A 6ew0H-5w3jB:
60.4		 6ew0H-5w3jB:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
LEU B 217
SER B 234
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
None
TA1  B 502 ( 4.9A)
TA1  B 502 (-3.7A)
 0.75A 6ew0H-5w3jB:
60.4		 6ew0H-5w3jB:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		5 / 12 VAL B  23
ASP B  26
GLU B  27
GLN B 279
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
TA1  B 502 ( 4.3A)
TA1  B 502 (-3.7A)
 1.09A 6ew0I-5w3jB:
60.4		 6ew0I-5w3jB:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		7 / 12 VAL B  23
ASP B  26
GLU B  27
LEU B 215
LEU B 217
SER B 234
LEU B 361
 TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
None
TA1  B 502 ( 4.9A)
TA1  B 502 (-3.7A)
 0.75A 6ew0I-5w3jB:
60.4		 6ew0I-5w3jB:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		4 / 5 GLY B  29
LEU B  30
TYR B 242
GLN B  43
 None
 1.23A 6ji6A-5w3jB:
undetectable		 6ji6A-5w3jB:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		4 / 5 GLY B 269
THR B 366
SER B 230
SER B 231
 None
 1.09A 6jmjA-5w3jB:
undetectable		 6jmjA-5w3jB:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5w3j TUBULIN BETA CHAIN
(Saccharomyces
cerevisiae) 		4 / 6 GLY B 269
THR B 366
SER B 230
SER B 231
 None
 1.10A 6jogA-5w3jB:
undetectable		 6jogA-5w3jB:
18.37