SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5w3v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)		 5w3v APOBEC3H
(Macaca
nemestrina) 		4 / 8 GLN B  33
LEU B 104
ARG B 105
LEU B  30
 None
 0.97A 1hk3A-5w3vB:
undetectable		 1hk3A-5w3vB:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_2
(ESTROGEN RECEPTOR)		 5w3v APOBEC3H
(Macaca
nemestrina) 		4 / 4 LEU B  80
THR B  81
ILE B  57
HIS B  54
 None
None
None
ZN  B 301 (-3.1A)
 1.32A 2jfaB-5w3vB:
undetectable		 2jfaB-5w3vB:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 5w3v APOBEC3H
(Macaca
nemestrina) 		3 / 3 THR B  43
PRO B  42
THR B  35
 None
 0.88A 316dC-5w3vB:
undetectable		 316dC-5w3vB:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 5w3v APOBEC3H
(Macaca
nemestrina) 		4 / 7 LYS B 162
LEU B 166
GLU B 165
VAL B  19
 None
None
None
A  F   2 ( 4.8A)
 0.98A 4tvtA-5w3vB:
undetectable		 4tvtA-5w3vB:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5w3v APOBEC3H
(Macaca
nemestrina) 		4 / 5 PRO B  36
LEU B  47
TYR B  79
PHE B 107
 None
 1.13A 5igjA-5w3vB:
undetectable		 5igjA-5w3vB:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		 5w3v APOBEC3H
(Macaca
nemestrina) 		5 / 10 ILE B 173
LEU B  80
VAL B 133
LEU B 126
SER B  83
 None
 1.27A 5tixB-5w3vB:
undetectable		 5tixB-5w3vB:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_B_RITB602_1
(CYTOCHROME P450 3A5)		 5w3v APOBEC3H
(Macaca
nemestrina) 		5 / 12 LEU B  92
ILE B 106
ALA B 108
ALA B  28
ILE B  48
 None
 1.08A 5veuB-5w3vB:
undetectable		 5veuB-5w3vB:
19.05