SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5w42'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 5w42 -
(-) 		4 / 7 ALA H  93
SER H  33
THR H  35
VAL H  37
 None
 0.42A 1dvxB-5w42H:
undetectable		 1dvxB-5w42H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 5w42 -
(-) 		4 / 7 ALA H  93
SER H  33
THR H  35
VAL H  37
 None
 0.32A 3ozkB-5w42H:
undetectable		 3ozkB-5w42H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_B_1FLB201_1
(TRANSTHYRETIN)		 5w42 -
(-) 		4 / 4 LYS H  23
ALA H  24
SER H  30
THR H  28
 None
 1.38A 4i89B-5w42H:
undetectable		 4i89B-5w42H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 5w42 -
(-) 		4 / 8 ALA H  93
SER H  33
THR H  35
VAL H  37
 None
 0.40A 4ik7B-5w42H:
undetectable		 4ik7B-5w42H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA606_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5w42 -
(-) 		4 / 5 GLU H 148
PHE H 146
HIS H 200
THR H 110
 None
 1.21A 6b58A-5w42H:
undetectable		 6b58A-5w42H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 5w42 -
(-) 		5 / 12 VAL H 207
THR H 205
VAL H 211
GLY H 118
VAL H 152
 None
 1.13A 6drzA-5w42H:
undetectable		 6drzA-5w42H:
undetectable