SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5w5f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 5w5f TAIL TUBE PROTEIN
GP19
(Enterobacteria
phage
T4
sensu
lato) 		5 / 11 LEU A 132
LEU A 157
VAL A 137
GLN A  89
ILE A  25
 None
 1.16A 2q6hA-5w5fA:
undetectable		 2q6hA-5w5fA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		 5w5f TAIL TUBE PROTEIN
GP19
(Enterobacteria
phage
T4
sensu
lato) 		5 / 11 LEU A 132
LEU A 157
VAL A 137
GLN A  89
ILE A  25
 None
 1.18A 2q72A-5w5fA:
undetectable		 2q72A-5w5fA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 5w5f TAIL TUBE PROTEIN
GP19
(Enterobacteria
phage
T4
sensu
lato) 		5 / 12 LEU A 132
LEU A 157
VAL A 137
GLN A  89
ILE A  25
 None
 1.16A 2qb4A-5w5fA:
undetectable		 2qb4A-5w5fA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 5w5f TAIL TUBE PROTEIN
GP19
(Enterobacteria
phage
T4
sensu
lato) 		5 / 11 LEU A 132
LEU A 157
VAL A 137
GLN A  89
ILE A  25
 None
 1.15A 2qeiA-5w5fA:
undetectable		 2qeiA-5w5fA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 5w5f TAIL TUBE PROTEIN
GP19
(Enterobacteria
phage
T4
sensu
lato) 		5 / 12 ILE A  91
ILE A 129
ILE A  25
LEU A  28
VAL A  71
 None
 1.19A 2qo5A-5w5fA:
undetectable		 2qo5A-5w5fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5w5f TAIL TUBE PROTEIN
GP19
(Enterobacteria
phage
T4
sensu
lato) 		4 / 7 ILE A  25
LEU A  28
PHE A  32
THR A  70
 None
 1.15A 2zxwN-5w5fA:
undetectable
2zxwW-5w5fA:
undetectable		 2zxwN-5w5fA:
15.76
2zxwW-5w5fA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5w5f TAIL TUBE PROTEIN
GP19
(Enterobacteria
phage
T4
sensu
lato) 		4 / 7 ILE A  25
LEU A  28
PHE A  32
THR A 156
 None
 0.99A 2zxwN-5w5fA:
undetectable
2zxwW-5w5fA:
undetectable		 2zxwN-5w5fA:
15.76
2zxwW-5w5fA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5w5f TAIL TUBE PROTEIN
GP19
(Enterobacteria
phage
T4
sensu
lato) 		4 / 7 ILE A  25
LEU A  28
PHE A  32
THR A 156
 None
 1.04A 3ag2N-5w5fA:
undetectable
3ag2W-5w5fA:
undetectable		 3ag2N-5w5fA:
15.76
3ag2W-5w5fA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5w5f TAIL TUBE PROTEIN
GP19
(Enterobacteria
phage
T4
sensu
lato) 		4 / 5 GLN A  35
THR A  33
THR A  39
LEU A 157
 None
 1.28A 3ce6A-5w5fA:
undetectable		 3ce6A-5w5fA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5w5f TAIL TUBE PROTEIN
GP19
(Enterobacteria
phage
T4
sensu
lato) 		4 / 5 GLN A  35
THR A  33
THR A  39
LEU A 157
 None
 1.25A 3ce6C-5w5fA:
undetectable		 3ce6C-5w5fA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_A_CAMA1419_0
(CYTOCHROME P450)		 5w5f TAIL TUBE PROTEIN
GP19
(Enterobacteria
phage
T4
sensu
lato) 		5 / 12 ILE A 127
LEU A 159
LEU A 132
GLY A 131
ILE A 112
 None
 1.01A 4c9lA-5w5fA:
undetectable		 4c9lA-5w5fA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_B_CAMB1419_0
(CYTOCHROME P450)		 5w5f TAIL TUBE PROTEIN
GP19
(Enterobacteria
phage
T4
sensu
lato) 		5 / 12 ILE A 127
LEU A 159
LEU A 132
GLY A 131
ILE A 112
 None
 1.03A 4c9lB-5w5fA:
undetectable		 4c9lB-5w5fA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 5w5f TAIL TUBE PROTEIN
GP19
(Enterobacteria
phage
T4
sensu
lato) 		5 / 12 ILE A 127
LEU A 159
LEU A 132
GLY A 131
ILE A 112
 None
 1.01A 4c9oA-5w5fA:
undetectable		 4c9oA-5w5fA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 5w5f TAIL TUBE PROTEIN
GP19
(Enterobacteria
phage
T4
sensu
lato) 		5 / 12 ILE A 127
LEU A 159
LEU A 132
GLY A 131
ILE A 112
 None
 1.00A 4c9oB-5w5fA:
undetectable		 4c9oB-5w5fA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5w5f TAIL TUBE PROTEIN
GP19
(Enterobacteria
phage
T4
sensu
lato) 		4 / 6 ILE A  25
LEU A  28
PHE A  32
THR A 156
 None
 1.04A 5b1aN-5w5fA:
undetectable
5b1aW-5w5fA:
undetectable		 5b1aN-5w5fA:
15.76
5b1aW-5w5fA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_B_ADNB502_2
(-)		 5w5f TAIL TUBE PROTEIN
GP19
(Enterobacteria
phage
T4
sensu
lato) 		4 / 4 GLN A  35
THR A  33
THR A  39
LEU A 157
 None
 1.39A 6f3mB-5w5fA:
undetectable		 6f3mB-5w5fA:
15.87