SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5w5x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5w5x 3C10 FAB' HEAVY
CHAIN
(Rattus
norvegicus) 		5 / 7 GLY H  54
PRO H  53
THR H  58
ILE H  51
GLY H  56
 None
 1.05A 1usqA-5w5xH:
undetectable		 1usqA-5w5xH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5w5x 3C10 FAB' HEAVY
CHAIN
(Rattus
norvegicus) 		4 / 6 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.79A 1usqB-5w5xH:
undetectable		 1usqB-5w5xH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5w5x 3C10 FAB' HEAVY
CHAIN
(Rattus
norvegicus) 		4 / 6 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.79A 1usqC-5w5xH:
undetectable		 1usqC-5w5xH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5w5x 3C10 FAB' HEAVY
CHAIN
(Rattus
norvegicus) 		4 / 6 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.80A 1usqD-5w5xH:
undetectable		 1usqD-5w5xH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5w5x 3C10 FAB' HEAVY
CHAIN
(Rattus
norvegicus) 		4 / 6 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.80A 1usqE-5w5xH:
undetectable		 1usqE-5w5xH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5w5x 3C10 FAB' HEAVY
CHAIN
(Rattus
norvegicus) 		4 / 6 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.87A 2jkjA-5w5xH:
undetectable		 2jkjA-5w5xH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5w5x 3C10 FAB' HEAVY
CHAIN
(Rattus
norvegicus) 		4 / 6 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.87A 2jkjB-5w5xH:
1.5		 2jkjB-5w5xH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5w5x 3C10 FAB' HEAVY
CHAIN
(Rattus
norvegicus) 		5 / 7 GLY H  54
PRO H  53
THR H  58
ILE H  51
GLY H  56
 None
 1.08A 2jklA-5w5xH:
undetectable		 2jklA-5w5xH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5w5x 3C10 FAB' HEAVY
CHAIN
(Rattus
norvegicus) 		4 / 6 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.86A 2jklB-5w5xH:
undetectable		 2jklB-5w5xH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5w5x 3C10 FAB' HEAVY
CHAIN
(Rattus
norvegicus) 		5 / 7 GLY H  54
PRO H  53
THR H  58
ILE H  51
GLY H  56
 None
 1.08A 2jklC-5w5xH:
undetectable		 2jklC-5w5xH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5w5x 3C10 FAB' HEAVY
CHAIN
(Rattus
norvegicus) 		5 / 7 GLY H  54
PRO H  53
THR H  58
ILE H  51
GLY H  56
 None
 1.07A 2jklD-5w5xH:
undetectable		 2jklD-5w5xH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5w5x 3C10 FAB' HEAVY
CHAIN
(Rattus
norvegicus) 		5 / 7 GLY H  54
PRO H  53
THR H  58
ILE H  51
GLY H  56
 None
 1.08A 2jklF-5w5xH:
undetectable		 2jklF-5w5xH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5w5x 3C10 FAB' HEAVY
CHAIN
(Rattus
norvegicus) 		5 / 12 VAL H 168
VAL H 186
SER H 184
ASN H 201
ASN H 160
 None
None
None
None
EDO  H 303 ( 4.1A)
 1.45A 2y03A-5w5xH:
undetectable		 2y03A-5w5xH:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5w5x 3C10 FAB' HEAVY
CHAIN
(Rattus
norvegicus) 		5 / 12 VAL H 168
VAL H 186
SER H 184
ASN H 201
ASN H 160
 None
None
None
None
EDO  H 303 ( 4.1A)
 1.48A 2y03B-5w5xH:
undetectable		 2y03B-5w5xH:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 5w5x 3C10 FAB' HEAVY
CHAIN
(Rattus
norvegicus) 		5 / 12 VAL H 168
VAL H 186
SER H 184
ASN H 201
ASN H 160
 None
None
None
None
EDO  H 303 ( 4.1A)
 1.42A 3nyaA-5w5xH:
undetectable		 3nyaA-5w5xH:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 5w5x 3C10 FAB' HEAVY
CHAIN
(Rattus
norvegicus) 		4 / 5 VAL H   2
TYR H  27
ARG H  98
TYR H 107
 PCA  H   1 ( 3.3A)
None
None
None
 0.34A 4m7kH-5w5xH:
23.8		 4m7kH-5w5xH:
undetectable