SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5w63'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 5w63 APOPTOSIS REGULATOR
BAX
(Ictalurus
punctatus) 		4 / 5 GLN A 154
THR A  54
HIS A  55
LEU A  21
 None
 1.35A 4lvcA-5w63A:
undetectable		 4lvcA-5w63A:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 5w63 APOPTOSIS REGULATOR
BAX
(Ictalurus
punctatus) 		4 / 5 GLN A 154
THR A  54
HIS A  55
LEU A  21
 None
 1.35A 4lvcC-5w63A:
undetectable		 4lvcC-5w63A:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 5w63 APOPTOSIS REGULATOR
BAX
(Ictalurus
punctatus) 		5 / 11 VAL A  20
ILE A  14
ILE A 148
ILE A 151
PHE A 113
 None
 1.32A 5hw8B-5w63A:
undetectable		 5hw8B-5w63A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 5w63 APOPTOSIS REGULATOR
BAX
(Ictalurus
punctatus) 		4 / 5 GLN A 154
THR A  54
HIS A  55
LEU A  21
 None
 1.36A 6gbnA-5w63A:
undetectable		 6gbnA-5w63A:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)		 5w63 APOPTOSIS REGULATOR
BAX
(Ictalurus
punctatus) 		4 / 5 GLN A 154
THR A  54
HIS A  55
LEU A  21
 None
 1.36A 6gbnD-5w63A:
undetectable		 6gbnD-5w63A:
9.93