SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5w66'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DHF_A_FOLA187_0 (DIHYDROFOLATE REDUCTASE)	5w66	RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN7 (Saccharomyces cerevisiae)	5 / 12	ILE P 314 GLN P 486 LEU P 338 TYR P 326 THR P 270	None	1.14A	1dhfA-5w66P: undetectable	1dhfA-5w66P: 14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_A_FOLA605_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5w66	RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN7 (Saccharomyces cerevisiae)	5 / 12	VAL P 257 LEU P 338 ILE P 331 LEU P 318 TYR P 446	None	1.13A	1qzfA-5w66P: undetectable	1qzfA-5w66P: 22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_B_FOLB609_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5w66	RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN7 (Saccharomyces cerevisiae)	5 / 12	VAL P 257 LEU P 338 ILE P 331 LEU P 318 TYR P 446	None	1.13A	1qzfB-5w66P: undetectable	1qzfB-5w66P: 22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_C_FOLC613_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5w66	RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN7 (Saccharomyces cerevisiae)	5 / 12	VAL P 257 LEU P 338 ILE P 331 LEU P 318 TYR P 446	None	1.12A	1qzfC-5w66P: undetectable	1qzfC-5w66P: 22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_D_FOLD617_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5w66	RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN7 (Saccharomyces cerevisiae)	5 / 12	VAL P 257 LEU P 338 ILE P 331 LEU P 318 TYR P 446	None	1.13A	1qzfD-5w66P: undetectable	1qzfD-5w66P: 22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_E_FOLE621_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5w66	RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN7 (Saccharomyces cerevisiae)	5 / 12	VAL P 257 LEU P 338 ILE P 331 LEU P 318 TYR P 446	None	1.13A	1qzfE-5w66P: undetectable	1qzfE-5w66P: 22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TYR_A_9CRA131_1 (TRANSTHYRETIN)	5w66	RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN7 (Saccharomyces cerevisiae)	4 / 6	LEU P 498 LEU P 488 SER P 485 THR P 481	None	1.33A	1tyrA-5w66P: undetectable	1tyrA-5w66P: 11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1U1J_A_C2FA773_0 (5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE)	5w66	RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN7 (Saccharomyces cerevisiae)	4 / 8	ARG P 289 LYS P 240 ASN P 228 HIS P 301	None	1.20A	1u1jA-5w66P: undetectable	1u1jA-5w66P: 21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W3M_A_FOLA1188_0 (DIHYDROFOLATE REDUCTASE)	5w66	RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN7 (Saccharomyces cerevisiae)	5 / 12	ILE P 314 GLN P 486 LEU P 338 TYR P 326 THR P 270	None	1.12A	2w3mA-5w66P: undetectable	2w3mA-5w66P: 14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FU9_A_ACTA311_0 (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)	5w66	RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN7 (Saccharomyces cerevisiae)	3 / 3	GLN P 435 THR P 344 THR P 343	None	0.76A	4fu9A-5w66P: undetectable	4fu9A-5w66P: 18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FUF_A_ACTA310_0 (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)	5w66	RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN7 (Saccharomyces cerevisiae)	3 / 3	GLN P 435 THR P 344 THR P 343	None	0.76A	4fufA-5w66P: undetectable	4fufA-5w66P: 18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OK1_A_198A1001_2 (ANDROGEN RECEPTOR)	5w66	RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN7 (Saccharomyces cerevisiae)	4 / 8	LEU P 119 LEU P 172 HIS P 171 ILE P 135	None	1.06A	4ok1A-5w66P: undetectable	4ok1A-5w66P: 18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PB1_A_RBVA501_1 (NUPC FAMILY PROTEIN)	5w66	RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN7 (Saccharomyces cerevisiae)	5 / 12	GLY P 224 ALA P 492 LEU P 304 SER P 163 ILE P 230	None	1.24A	4pb1A-5w66P: undetectable	4pb1A-5w66P: 21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PD5_A_GEOA501_1 (NUPC FAMILY PROTEIN)	5w66	RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN7 (Saccharomyces cerevisiae)	5 / 12	GLY P 224 ALA P 492 LEU P 304 SER P 163 ILE P 230	None	1.15A	4pd5A-5w66P: undetectable	4pd5A-5w66P: 21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HBS_A_RTLA201_1 (RETINOL-BINDING PROTEIN 1)	5w66	RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN7 (Saccharomyces cerevisiae)	4 / 8	LEU P 487 THR P 270 TYR P 309 GLN P 250	None	1.09A	5hbsA-5w66P: undetectable	5hbsA-5w66P: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XOO_A_ADNA506_1 (GLYCOSAMINOGLYCAN XYLOSYLKINASE)	5w66	RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN7 (Saccharomyces cerevisiae)	4 / 6	TYR P 210 LEU P 105 GLU P 151 LEU P 154	None	1.40A	5xooA-5w66P: undetectable	5xooA-5w66P: 10.18