SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5w6g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y03_A_5FWA601_1 (BETA-1 ADRENERGIC RECEPTOR)	5w6g	6649 ANTIBODY HEAVY CHAIN (Homo sapiens)	5 / 12	VAL H 175 VAL H 194 SER H 192 ASN H 209 ASN H 167	None	1.41A	2y03A-5w6gH: undetectable	2y03A-5w6gH: 13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y03_B_5FWB601_1 (BETA-1 ADRENERGIC RECEPTOR)	5w6g	6649 ANTIBODY HEAVY CHAIN (Homo sapiens)	5 / 12	VAL H 175 VAL H 194 SER H 192 ASN H 209 ASN H 167	None	1.45A	2y03B-5w6gH: undetectable	2y03B-5w6gH: 13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JWQ_B_VIAB901_1 (CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA)	5w6g	6649 ANTIBODY HEAVY CHAIN (Homo sapiens)	5 / 11	TYR H 157 HIS H 212 LEU H 120 ALA H 180 THR H 92	None	1.19A	3jwqB-5w6gH: undetectable 3jwqC-5w6gH: undetectable	3jwqB-5w6gH: 12.12 3jwqC-5w6gH: 12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NYA_A_JTZA1203_1 (BETA-2 ADRENERGIC RECEPTOR, LYSOZYME)	5w6g	6649 ANTIBODY HEAVY CHAIN (Homo sapiens)	5 / 12	VAL H 175 VAL H 194 SER H 192 ASN H 209 ASN H 167	None	1.42A	3nyaA-5w6gH: undetectable	3nyaA-5w6gH: 10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LDO_A_ALEA1402_1 (LYSOZYME, BETA-2 ADRENERGIC RECEPTOR)	5w6g	6649 ANTIBODY HEAVY CHAIN (Homo sapiens)	5 / 10	VAL H 175 VAL H 194 SER H 192 ASN H 209 ASN H 167	None	1.46A	4ldoA-5w6gH: undetectable	4ldoA-5w6gH: 9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6H7M_B_68HB405_0 (BETA-1 ADRENERGIC RECEPTOR)	5w6g	6649 ANTIBODY HEAVY CHAIN (Homo sapiens)	5 / 12	VAL H 175 VAL H 194 SER H 192 ASN H 209 ASN H 167	None	1.42A	6h7mB-5w6gH: undetectable	6h7mB-5w6gH: 19.78

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2Y03_A_5FWA601_1","BETA-1 ADRENERGIC RECEPTOR","5w6g","6649 ANTIBODY HEAVY CHAIN","Homo sapiens",5,"VAL H 175;VAL H 194;SER H 192;ASN H 209;ASN H 167","None","1.41A","2y03A-5w6gH:undetectable","2y03A-5w6gH:13.95"],["2Y03_B_5FWB601_1","BETA-1 ADRENERGIC RECEPTOR","5w6g","6649 ANTIBODY HEAVY CHAIN","Homo sapiens",5,"VAL H 175;VAL H 194;SER H 192;ASN H 209;ASN H 167","None","1.45A","2y03B-5w6gH:undetectable","2y03B-5w6gH:13.95"],["3JWQ_B_VIAB901_1","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA;CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA","5w6g","6649 ANTIBODY HEAVY CHAIN","Homo sapiens",5,"TYR H 157;HIS H 212;LEU H 120;ALA H 180;THR H  92","None","1.19A","3jwqB-5w6gH:undetectable;3jwqC-5w6gH:undetectable","3jwqB-5w6gH:12.12;3jwqC-5w6gH:12.12"],["3NYA_A_JTZA1203_1","BETA-2 ADRENERGIC RECEPTOR, LYSOZYME","5w6g","6649 ANTIBODY HEAVY CHAIN","Homo sapiens",5,"VAL H 175;VAL H 194;SER H 192;ASN H 209;ASN H 167","None","1.42A","3nyaA-5w6gH:undetectable","3nyaA-5w6gH:10.91"],["4LDO_A_ALEA1402_1","LYSOZYME, BETA-2 ADRENERGIC RECEPTOR","5w6g","6649 ANTIBODY HEAVY CHAIN","Homo sapiens",5,"VAL H 175;VAL H 194;SER H 192;ASN H 209;ASN H 167","None","1.46A","4ldoA-5w6gH:undetectable","4ldoA-5w6gH:9.19"],["6H7M_B_68HB405_0","BETA-1 ADRENERGIC RECEPTOR","5w6g","6649 ANTIBODY HEAVY CHAIN","Homo sapiens",5,"VAL H 175;VAL H 194;SER H 192;ASN H 209;ASN H 167","None","1.42A","6h7mB-5w6gH:undetectable","6h7mB-5w6gH:19.78"]]