SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5w6y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 5w6y CHORISMATE MUTASE
(Physcomitrella
patens) 		4 / 8 ARG A 135
GLU A 141
HIS A 216
SER A 212
 None
 1.34A 1nx9B-5w6yA:
undetectable		 1nx9B-5w6yA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 5w6y CHORISMATE MUTASE
(Physcomitrella
patens) 		4 / 8 ARG A 135
GLU A 141
HIS A 216
SER A 212
 None
 1.33A 1nx9C-5w6yA:
undetectable		 1nx9C-5w6yA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 5w6y CHORISMATE MUTASE
(Physcomitrella
patens) 		4 / 8 ARG A 135
GLU A 141
HIS A 216
SER A 212
 None
 1.33A 1nx9D-5w6yA:
undetectable		 1nx9D-5w6yA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB504_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5w6y CHORISMATE MUTASE
(Physcomitrella
patens) 		4 / 7 LEU A 249
ILE A 245
ALA A 222
ILE A 170
 None
 0.86A 1oniB-5w6yA:
undetectable
1oniC-5w6yA:
undetectable		 1oniB-5w6yA:
20.90
1oniC-5w6yA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 5w6y CHORISMATE MUTASE
(Physcomitrella
patens) 		4 / 6 MET A 122
VAL A 119
LEU A 118
PHE A 109
 None
 1.03A 1x8vA-5w6yA:
1.0		 1x8vA-5w6yA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5w6y CHORISMATE MUTASE
(Physcomitrella
patens) 		4 / 7 VAL A 254
VAL A 299
MET A 179
ARG A  82
 None
 1.31A 3ms9B-5w6yA:
undetectable		 3ms9B-5w6yA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H4D_A_BBIA403_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 5w6y CHORISMATE MUTASE
(Physcomitrella
patens) 		4 / 6 PHE A 114
GLU A 120
PHE A 145
VAL A 205
 None
 1.42A 5h4dA-5w6yA:
undetectable		 5h4dA-5w6yA:
20.60