SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5w7i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2001_1
(SERUM ALBUMIN)		 5w7i PALMITOYLTRANSFERASE
ZDHHC17
(Homo
sapiens) 		4 / 8 SER A 242
ALA A 232
ALA A 265
LEU A 262
 None
 0.85A 2bxmA-5w7iA:
undetectable		 2bxmA-5w7iA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_B_017B203_1
(HIV-1 PROTEASE)		 5w7i PALMITOYLTRANSFERASE
ZDHHC17
(Homo
sapiens) 		4 / 7 GLU A 156
PRO A 193
MET A 186
GLY A 157
 None
 1.29A 2hs1B-5w7iA:
undetectable		 2hs1B-5w7iA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_1
(FIV PROTEASE)		 5w7i PALMITOYLTRANSFERASE
ZDHHC17
(Homo
sapiens) 		5 / 9 GLY A 147
ALA A 148
ASP A 149
ILE A 115
LEU A 143
 None
 0.99A 3ogpA-5w7iA:
undetectable		 3ogpA-5w7iA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 5w7i PALMITOYLTRANSFERASE
ZDHHC17
(Homo
sapiens) 		3 / 3 LYS A 266
LEU A 229
ASP A 252
 None
 0.90A 5zv2A-5w7iA:
undetectable		 5zv2A-5w7iA:
18.70