SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5w7k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 5w7k OXAG
(Penicillium
oxalicum) 		4 / 8 LEU A  64
ASN A 102
LEU A  48
LEU A  50
 None
 1.08A 1e7cA-5w7kA:
undetectable		 1e7cA-5w7kA:
7.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 5w7k OXAG
(Penicillium
oxalicum) 		6 / 12 ALA A  54
GLY A  56
ILE A  83
SER A  84
ALA A 110
PHE A 132
 SAH  A 301 (-3.4A)
SAH  A 301 (-3.4A)
SAH  A 301 (-3.9A)
None
SAH  A 301 (-3.4A)
SAH  A 301 (-4.6A)
 0.82A 1ve3A-5w7kA:
19.5		 1ve3A-5w7kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 5w7k OXAG
(Penicillium
oxalicum) 		6 / 12 TYR A  20
ALA A  54
ILE A  83
SER A  84
ALA A 110
PHE A 132
 SAH  A 301 (-4.6A)
SAH  A 301 (-3.4A)
SAH  A 301 (-3.9A)
None
SAH  A 301 (-3.4A)
SAH  A 301 (-4.6A)
 1.07A 1ve3A-5w7kA:
19.5		 1ve3A-5w7kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 5w7k OXAG
(Penicillium
oxalicum) 		6 / 12 ALA A  54
GLY A  56
ILE A  83
SER A  84
ALA A 110
PHE A 132
 SAH  A 301 (-3.4A)
SAH  A 301 (-3.4A)
SAH  A 301 (-3.9A)
None
SAH  A 301 (-3.4A)
SAH  A 301 (-4.6A)
 0.84A 1ve3B-5w7kA:
20.2		 1ve3B-5w7kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 5w7k OXAG
(Penicillium
oxalicum) 		6 / 12 TYR A  20
ALA A  54
ILE A  83
SER A  84
ALA A 110
PHE A 132
 SAH  A 301 (-4.6A)
SAH  A 301 (-3.4A)
SAH  A 301 (-3.9A)
None
SAH  A 301 (-3.4A)
SAH  A 301 (-4.6A)
 1.11A 1ve3B-5w7kA:
20.2		 1ve3B-5w7kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 5w7k OXAG
(Penicillium
oxalicum) 		5 / 12 ASP A  52
ILE A  83
SER A  84
ALA A 110
PHE A 132
 None
SAH  A 301 (-3.9A)
None
SAH  A 301 (-3.4A)
SAH  A 301 (-4.6A)
 1.15A 2ejtA-5w7kA:
12.5		 2ejtA-5w7kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8L_A_SAMA400_1
(HYPOTHETICAL PROTEIN
LMO1582)		 5w7k OXAG
(Penicillium
oxalicum) 		4 / 4 THR A  27
THR A  57
ASP A  82
ASP A 109
 SAH  A 301 (-2.9A)
None
SAH  A 301 (-2.7A)
SAH  A 301 (-3.6A)
 0.97A 2f8lA-5w7kA:
13.6		 2f8lA-5w7kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 5w7k OXAG
(Penicillium
oxalicum) 		5 / 11 GLY A  58
THR A  57
GLU A  62
THR A  31
GLU A  24
 None
 1.19A 2fn1B-5w7kA:
undetectable		 2fn1B-5w7kA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 5w7k OXAG
(Penicillium
oxalicum) 		4 / 6 THR A  27
THR A  57
ASP A  82
ASP A 109
 SAH  A 301 (-2.9A)
None
SAH  A 301 (-2.7A)
SAH  A 301 (-3.6A)
 1.04A 2okcA-5w7kA:
12.6		 2okcA-5w7kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 5w7k OXAG
(Penicillium
oxalicum) 		4 / 6 THR A  27
THR A  57
ASP A  82
ASP A 109
 SAH  A 301 (-2.9A)
None
SAH  A 301 (-2.7A)
SAH  A 301 (-3.6A)
 1.08A 2okcB-5w7kA:
12.7		 2okcB-5w7kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRH_A_NIOA200_1
(PROTEIN HP0721)		 5w7k OXAG
(Penicillium
oxalicum) 		4 / 7 GLY A  89
ARG A  93
MET A  21
LEU A  87
 None
None
None
SAH  A 301 (-4.4A)
 0.95A 2xrhA-5w7kA:
undetectable		 2xrhA-5w7kA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5w7k OXAG
(Penicillium
oxalicum) 		5 / 12 LEU A  50
PHE A 124
ILE A  35
GLY A  39
SER A  43
 None
 1.03A 3kk6A-5w7kA:
undetectable		 3kk6A-5w7kA:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5w7k OXAG
(Penicillium
oxalicum) 		5 / 12 LEU A  50
PHE A 124
ILE A  35
GLY A  39
SER A  43
 None
 1.22A 3kk6B-5w7kA:
undetectable		 3kk6B-5w7kA:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5w7k OXAG
(Penicillium
oxalicum) 		5 / 12 LEU A  50
PHE A 124
ILE A  35
GLY A  39
SER A  43
 None
 1.25A 3n8xA-5w7kA:
undetectable		 3n8xA-5w7kA:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_I_SAMI228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 5w7k OXAG
(Penicillium
oxalicum) 		6 / 12 GLY A  81
ALA A 105
ASP A 109
ALA A 110
ASP A  52
GLU A  62
 None
None
SAH  A 301 (-3.6A)
SAH  A 301 (-3.4A)
None
None
 1.37A 3nvkI-5w7kA:
13.6		 3nvkI-5w7kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5w7k OXAG
(Penicillium
oxalicum) 		5 / 12 ALA A  54
GLY A  56
SER A  84
ASP A 109
ALA A 126
 SAH  A 301 (-3.4A)
SAH  A 301 (-3.4A)
None
SAH  A 301 (-3.6A)
SAH  A 301 (-3.5A)
 0.71A 3ou6A-5w7kA:
15.6		 3ou6A-5w7kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5w7k OXAG
(Penicillium
oxalicum) 		3 / 3 GLY A  56
ASP A  82
ASP A 109
 SAH  A 301 (-3.4A)
SAH  A 301 (-2.7A)
SAH  A 301 (-3.6A)
 0.41A 3ou7C-5w7kA:
15.4		 3ou7C-5w7kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5w7k OXAG
(Penicillium
oxalicum) 		5 / 12 GLY A  56
ASP A  82
ILE A  83
ASP A 109
ALA A 128
 SAH  A 301 (-3.4A)
SAH  A 301 (-2.7A)
SAH  A 301 (-3.9A)
SAH  A 301 (-3.6A)
SAH  A 301 ( 3.9A)
 0.62A 4iv8A-5w7kA:
18.8		 4iv8A-5w7kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5w7k OXAG
(Penicillium
oxalicum) 		5 / 12 GLY A  56
ASP A  82
ILE A  83
ASP A 109
ALA A 128
 SAH  A 301 (-3.4A)
SAH  A 301 (-2.7A)
SAH  A 301 (-3.9A)
SAH  A 301 (-3.6A)
SAH  A 301 ( 3.9A)
 0.62A 4iv8B-5w7kA:
18.8		 4iv8B-5w7kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 5w7k OXAG
(Penicillium
oxalicum) 		4 / 4 ILE A  35
SER A  38
ASP A  52
ASP A  82
 None
None
None
SAH  A 301 (-2.7A)
 1.21A 4krhB-5w7kA:
17.7		 4krhB-5w7kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 5w7k OXAG
(Penicillium
oxalicum) 		4 / 7 LEU A 120
MET A 108
LEU A  53
ILE A  35
 None
 0.80A 4ojbA-5w7kA:
undetectable		 4ojbA-5w7kA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 5w7k OXAG
(Penicillium
oxalicum) 		4 / 8 LEU A 146
MET A 108
LEU A  53
ILE A  35
 None
 1.03A 4ok1A-5w7kA:
undetectable		 4ok1A-5w7kA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_1
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 5w7k OXAG
(Penicillium
oxalicum) 		4 / 4 ASP A  52
GLY A  56
ASP A  82
ASP A 109
 None
SAH  A 301 (-3.4A)
SAH  A 301 (-2.7A)
SAH  A 301 (-3.6A)
 0.69A 5e72A-5w7kA:
16.9		 5e72A-5w7kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5w7k OXAG
(Penicillium
oxalicum) 		6 / 12 ALA A  54
SER A  84
ALA A 110
ALA A 126
SER A 131
PRO A 133
 SAH  A 301 (-3.4A)
None
SAH  A 301 (-3.4A)
SAH  A 301 (-3.5A)
SAH  A 301 ( 4.5A)
None
 0.52A 5jglA-5w7kA:
29.5		 5jglA-5w7kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5w7k OXAG
(Penicillium
oxalicum) 		5 / 12 THR A  27
ALA A  54
SER A  84
ALA A 110
ALA A 126
 SAH  A 301 (-2.9A)
SAH  A 301 (-3.4A)
None
SAH  A 301 (-3.4A)
SAH  A 301 (-3.5A)
 0.67A 5jglA-5w7kA:
29.5		 5jglA-5w7kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5w7k OXAG
(Penicillium
oxalicum) 		6 / 12 ALA A  54
GLY A  56
ALA A 110
ALA A 126
SER A 131
PRO A 133
 SAH  A 301 (-3.4A)
SAH  A 301 (-3.4A)
SAH  A 301 (-3.4A)
SAH  A 301 (-3.5A)
SAH  A 301 ( 4.5A)
None
 0.46A 5jglB-5w7kA:
29.8		 5jglB-5w7kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5w7k OXAG
(Penicillium
oxalicum) 		5 / 12 THR A  27
ALA A  54
GLY A  56
ALA A 110
ALA A 126
 SAH  A 301 (-2.9A)
SAH  A 301 (-3.4A)
SAH  A 301 (-3.4A)
SAH  A 301 (-3.4A)
SAH  A 301 (-3.5A)
 0.68A 5jglB-5w7kA:
29.8		 5jglB-5w7kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7J_A_TESA502_0
(CYTOCHROME P450)		 5w7k OXAG
(Penicillium
oxalicum) 		4 / 7 LEU A 263
LEU A 259
ALA A 232
ALA A 231
 None
 0.87A 6a7jA-5w7kA:
undetectable		 6a7jA-5w7kA:
17.20