SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5w7l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)
5w7l N,N'-DIACETYLBACILLI
OSAMINYL-1-PHOSPHATE
TRANSFERASE

(Campylobacter
concisus)
4 / 6 ILE A 172
ASP A 169
GLY A 135
VAL A 101
None
1.08A 4oltA-5w7lA:
undetectable
4oltA-5w7lA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)
5w7l N,N'-DIACETYLBACILLI
OSAMINYL-1-PHOSPHATE
TRANSFERASE

(Campylobacter
concisus)
4 / 7 ILE A 136
GLY A 135
ASP A 169
PHE A 166
PG4  A 305 (-4.4A)
None
None
None
0.78A 5hieA-5w7lA:
undetectable
5hieA-5w7lA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)
5w7l N,N'-DIACETYLBACILLI
OSAMINYL-1-PHOSPHATE
TRANSFERASE

(Campylobacter
concisus)
4 / 6 MET A  57
GLU A  94
GLY A 135
GLY A 110
None
PO4  A 302 ( 3.3A)
None
None
0.86A 5x7pB-5w7lA:
undetectable
5x7pB-5w7lA:
5.18