SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5w8o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CET_A_CLQA1001_0
(PROTEIN (L-LACTATE
DEHYDROGENASE))		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		5 / 9 VAL A 301
GLY A 300
ALA A 304
ILE A 168
GLU A 165
 None
 1.03A 1cetA-5w8oA:
undetectable		 1cetA-5w8oA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		5 / 11 LEU A 164
VAL A 312
VAL A 153
GLY A 177
LEU A 331
 None
 1.26A 1fkpA-5w8oA:
undetectable		 1fkpA-5w8oA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JKH_A_EFZA999_1
(HIV-1 RT, A-CHAIN
HIV-1 RT, B-CHAIN)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		5 / 11 LEU A 164
VAL A 312
VAL A 153
GLY A 177
LEU A 331
 None
 1.10A 1jkhA-5w8oA:
0.4
1jkhB-5w8oA:
undetectable		 1jkhA-5w8oA:
20.93
1jkhB-5w8oA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 6 PHE A 277
ALA A 279
GLY A 280
TYR A 282
 None
 1.13A 1l5qB-5w8oA:
2.4		 1l5qB-5w8oA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 6 PHE A 277
ALA A 279
GLY A 280
TYR A 282
 None
 1.14A 1l7xA-5w8oA:
undetectable		 1l7xA-5w8oA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 6 PHE A 277
ALA A 279
GLY A 280
TYR A 282
 None
 1.12A 1l7xB-5w8oA:
undetectable		 1l7xB-5w8oA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		5 / 12 ILE A 179
LEU A 305
GLY A 155
GLY A 160
LEU A 331
 None
 0.94A 1liiA-5w8oA:
undetectable		 1liiA-5w8oA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWF_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		5 / 9 LEU A 164
VAL A 312
VAL A 153
GLY A 177
LEU A 331
 None
 1.36A 1lwfA-5w8oA:
1.0		 1lwfA-5w8oA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		5 / 12 GLY A 216
GLY A 214
TYR A 213
TYR A 212
LEU A 273
 None
 1.04A 1p91B-5w8oA:
undetectable		 1p91B-5w8oA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 7 LEU A 368
ASP A  91
THR A  92
HIS A  65
 None
 0.97A 1v55C-5w8oA:
undetectable
1v55N-5w8oA:
undetectable
1v55P-5w8oA:
undetectable		 1v55C-5w8oA:
19.78
1v55N-5w8oA:
20.38
1v55P-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA1_1
(CES1 PROTEIN)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		6 / 12 GLY A 159
GLY A 160
LEU A 164
LEU A 289
LEU A 327
HIS A 350
 None
 1.28A 1ya4A-5w8oA:
12.7		 1ya4A-5w8oA:
22.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_A_CSCA1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		7 / 11 LEU A  60
ARG A 227
TYR A 234
ARG A 243
HIS A 350
ASP A 351
PHE A 353
 None
 0.94A 2vavA-5w8oA:
45.7		 2vavA-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_A_CSCA1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		7 / 11 LEU A  60
THR A  61
ARG A 227
TYR A 234
ARG A 243
HIS A 350
PHE A 353
 None
 0.79A 2vavA-5w8oA:
45.7		 2vavA-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_B_CSCB1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		8 / 12 LEU A  60
ARG A 227
TYR A 234
ARG A 243
GLN A 269
HIS A 350
ASP A 351
PHE A 353
 None
 0.99A 2vavB-5w8oA:
45.6		 2vavB-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_B_CSCB1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		8 / 12 LEU A  60
THR A  61
ARG A 227
TYR A 234
ARG A 243
GLN A 269
HIS A 350
PHE A 353
 None
 0.90A 2vavB-5w8oA:
45.6		 2vavB-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_C_CSCC1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		9 / 12 LEU A  60
THR A  61
ARG A 227
TYR A 234
ARG A 243
TYR A 265
GLN A 269
HIS A 350
PHE A 353
 None
 0.92A 2vavC-5w8oA:
45.6		 2vavC-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_D_CSCD1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		9 / 12 LEU A  60
THR A  61
ARG A 227
TYR A 234
ARG A 243
TYR A 265
GLN A 269
HIS A 350
PHE A 353
 None
 0.92A 2vavD-5w8oA:
45.8		 2vavD-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_E_CSCE1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		8 / 12 ARG A 227
TYR A 234
ARG A 243
TYR A 265
GLN A 269
HIS A 350
ASP A 351
PHE A 353
 None
 1.02A 2vavE-5w8oA:
45.5		 2vavE-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_E_CSCE1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		8 / 12 THR A  61
ARG A 227
TYR A 234
ARG A 243
TYR A 265
GLN A 269
HIS A 350
PHE A 353
 None
 0.95A 2vavE-5w8oA:
45.5		 2vavE-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_F_CSCF1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		7 / 12 ARG A 227
TYR A 234
ARG A 243
TYR A 265
GLN A 269
ASP A 351
PHE A 353
 None
 1.04A 2vavF-5w8oA:
45.7		 2vavF-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_F_CSCF1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		7 / 12 THR A  61
ARG A 227
TYR A 234
ARG A 243
TYR A 265
GLN A 269
PHE A 353
 None
 1.00A 2vavF-5w8oA:
45.7		 2vavF-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_G_CSCG1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		8 / 12 ARG A 227
TYR A 234
ARG A 243
TYR A 265
GLN A 269
HIS A 350
ASP A 351
PHE A 353
 None
 0.99A 2vavG-5w8oA:
45.8		 2vavG-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_G_CSCG1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		8 / 12 THR A  61
ARG A 227
TYR A 234
ARG A 243
TYR A 265
GLN A 269
HIS A 350
PHE A 353
 None
 0.95A 2vavG-5w8oA:
45.8		 2vavG-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		7 / 12 LEU A  60
ARG A 227
TYR A 234
ARG A 243
TYR A 265
HIS A 350
ASP A 351
 None
 0.93A 2vavH-5w8oA:
45.7		 2vavH-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		7 / 12 LEU A  60
THR A  61
ARG A 227
TYR A 234
ARG A 243
TYR A 265
HIS A 350
 None
 0.81A 2vavH-5w8oA:
45.7		 2vavH-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_I_CSCI1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		8 / 12 LEU A  60
ARG A 227
TYR A 234
ARG A 243
GLN A 269
HIS A 350
ASP A 351
PHE A 353
 None
 0.99A 2vavI-5w8oA:
45.6		 2vavI-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_I_CSCI1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		8 / 12 LEU A  60
THR A  61
ARG A 227
TYR A 234
ARG A 243
GLN A 269
HIS A 350
PHE A 353
 None
 0.90A 2vavI-5w8oA:
45.6		 2vavI-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		8 / 12 LEU A  60
ARG A 227
TYR A 234
ARG A 243
TYR A 265
GLN A 269
ASP A 351
PHE A 353
 None
 1.03A 2vavJ-5w8oA:
45.5		 2vavJ-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		8 / 12 LEU A  60
THR A  61
ARG A 227
TYR A 234
ARG A 243
TYR A 265
GLN A 269
PHE A 353
 None
 0.95A 2vavJ-5w8oA:
45.5		 2vavJ-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		8 / 12 LEU A  60
THR A  61
ARG A 227
TYR A 234
ARG A 243
TYR A 265
GLN A 269
PHE A 353
 None
 0.95A 2vavK-5w8oA:
45.3		 2vavK-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		8 / 12 ARG A 227
TYR A 234
ARG A 243
TYR A 265
GLN A 269
HIS A 350
ASP A 351
PHE A 353
 None
 1.01A 2vavL-5w8oA:
45.5		 2vavL-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		8 / 12 THR A  61
ARG A 227
TYR A 234
ARG A 243
TYR A 265
GLN A 269
HIS A 350
PHE A 353
 None
 0.95A 2vavL-5w8oA:
45.5		 2vavL-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_A_CSCA1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		9 / 12 LEU A  60
THR A  61
ARG A 227
TYR A 234
ARG A 243
TYR A 265
GLN A 269
HIS A 350
PHE A 353
 None
 1.02A 2vaxA-5w8oA:
6.2		 2vaxA-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_B_CSCB1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		8 / 12 LEU A  60
THR A  61
ARG A 227
TYR A 234
TYR A 265
GLN A 269
HIS A 350
PHE A 353
 None
 0.88A 2vaxB-5w8oA:
45.6		 2vaxB-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_C_CSCC1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		8 / 12 THR A  61
ARG A 227
TYR A 234
ARG A 243
TYR A 265
GLN A 269
HIS A 350
PHE A 353
 None
 1.08A 2vaxC-5w8oA:
45.6		 2vaxC-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_D_CSCD1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		6 / 12 LEU A  60
ARG A 227
TYR A 265
GLN A 269
HIS A 350
PHE A 353
 None
 0.97A 2vaxD-5w8oA:
45.7		 2vaxD-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_D_CSCD1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		7 / 12 LEU A  60
THR A  61
ARG A 227
TYR A 234
TYR A 265
HIS A 350
PHE A 353
 None
 0.68A 2vaxD-5w8oA:
45.7		 2vaxD-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_E_CSCE1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		9 / 12 LEU A  60
THR A  61
ARG A 227
TYR A 234
ARG A 243
TYR A 265
GLN A 269
HIS A 350
PHE A 353
 None
 1.01A 2vaxE-5w8oA:
45.5		 2vaxE-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_F_CSCF1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		8 / 12 LEU A  60
THR A  61
ARG A 227
TYR A 234
ARG A 243
GLN A 269
HIS A 350
PHE A 353
 None
 0.98A 2vaxF-5w8oA:
45.8		 2vaxF-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_F_CSCF1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		8 / 12 LEU A  60
THR A  61
ARG A 227
TYR A 234
ARG A 243
TYR A 265
HIS A 350
PHE A 353
 None
 0.91A 2vaxF-5w8oA:
45.8		 2vaxF-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_G_CSCG1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		8 / 12 LEU A  60
THR A  61
ARG A 227
TYR A 234
ARG A 243
GLN A 269
HIS A 350
PHE A 353
 None
 1.02A 2vaxG-5w8oA:
45.8		 2vaxG-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		9 / 12 LEU A  60
THR A  61
ARG A 227
TYR A 234
ARG A 243
TYR A 265
GLN A 269
HIS A 350
PHE A 353
 None
 0.88A 2vaxH-5w8oA:
45.9		 2vaxH-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_I_CSCI1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		8 / 12 LEU A  60
THR A  61
ARG A 227
TYR A 234
TYR A 265
GLN A 269
HIS A 350
PHE A 353
 None
 0.90A 2vaxI-5w8oA:
45.7		 2vaxI-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		7 / 12 LEU A  60
ARG A 227
ARG A 243
TYR A 265
GLN A 269
HIS A 350
PHE A 353
 None
 1.13A 2vaxJ-5w8oA:
45.6		 2vaxJ-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		8 / 12 LEU A  60
THR A  61
ARG A 227
TYR A 234
ARG A 243
TYR A 265
HIS A 350
PHE A 353
 None
 0.82A 2vaxJ-5w8oA:
45.6		 2vaxJ-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		8 / 12 LEU A  60
THR A  61
ARG A 227
TYR A 234
ARG A 243
TYR A 265
HIS A 350
PHE A 353
 None
 0.90A 2vaxK-5w8oA:
45.6		 2vaxK-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		7 / 12 LEU A  60
TYR A 234
ARG A 243
TYR A 265
GLN A 269
HIS A 350
PHE A 353
 None
 1.15A 2vaxK-5w8oA:
45.6		 2vaxK-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		7 / 12 THR A  61
ARG A 227
TYR A 234
ARG A 243
GLN A 269
HIS A 350
PHE A 353
 None
 0.99A 2vaxL-5w8oA:
45.7		 2vaxL-5w8oA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		7 / 12 THR A  61
ARG A 227
TYR A 234
ARG A 243
TYR A 265
HIS A 350
PHE A 353
 None
 0.89A 2vaxL-5w8oA:
45.7		 2vaxL-5w8oA:
33.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 ASP A  91
THR A  92
HIS A  65
LEU A 368
 None
 0.97A 3ablA-5w8oA:
undetectable
3ablC-5w8oA:
undetectable
3ablP-5w8oA:
undetectable		 3ablA-5w8oA:
20.38
3ablC-5w8oA:
19.78
3ablP-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 LEU A 368
ASP A  91
THR A  92
HIS A  65
 None
 0.99A 3ablC-5w8oA:
undetectable
3ablN-5w8oA:
undetectable
3ablP-5w8oA:
undetectable		 3ablC-5w8oA:
19.78
3ablN-5w8oA:
20.38
3ablP-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 ASP A  91
THR A  92
HIS A  65
LEU A 368
 None
 0.94A 3abmA-5w8oA:
undetectable
3abmC-5w8oA:
undetectable
3abmP-5w8oA:
undetectable		 3abmA-5w8oA:
20.38
3abmC-5w8oA:
19.78
3abmP-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 LEU A 368
ASP A  91
THR A  92
HIS A  65
 None
 1.00A 3asnC-5w8oA:
undetectable
3asnN-5w8oA:
undetectable
3asnP-5w8oA:
undetectable		 3asnC-5w8oA:
19.78
3asnN-5w8oA:
20.38
3asnP-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 ASP A  91
THR A  92
HIS A  65
LEU A 368
 None
 1.03A 3asoA-5w8oA:
undetectable
3asoC-5w8oA:
undetectable
3asoP-5w8oA:
undetectable		 3asoA-5w8oA:
20.38
3asoC-5w8oA:
19.78
3asoP-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 LEU A 368
ASP A  91
THR A  92
HIS A  65
 None
 1.02A 3asoC-5w8oA:
undetectable
3asoN-5w8oA:
undetectable
3asoP-5w8oA:
undetectable		 3asoC-5w8oA:
19.78
3asoN-5w8oA:
20.38
3asoP-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 5 PHE A 277
ALA A 279
GLY A 280
TYR A 282
 None
 1.19A 3bcrA-5w8oA:
3.6		 3bcrA-5w8oA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 6 PHE A 277
ALA A 279
GLY A 280
TYR A 282
 None
 1.13A 3dd1A-5w8oA:
undetectable		 3dd1A-5w8oA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 6 PHE A 277
ALA A 279
GLY A 280
TYR A 282
 None
 1.13A 3dd1B-5w8oA:
undetectable		 3dd1B-5w8oA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 6 PHE A 277
ALA A 279
GLY A 280
TYR A 282
 None
 1.13A 3ddsA-5w8oA:
undetectable		 3ddsA-5w8oA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 6 PHE A 277
ALA A 279
GLY A 280
TYR A 282
 None
 1.13A 3ddsB-5w8oA:
undetectable		 3ddsB-5w8oA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 6 PHE A 277
ALA A 279
GLY A 280
TYR A 282
 None
 1.13A 3ddwA-5w8oA:
undetectable		 3ddwA-5w8oA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 6 PHE A 277
ALA A 279
GLY A 280
TYR A 282
 None
 1.15A 3ddwB-5w8oA:
undetectable		 3ddwB-5w8oA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		5 / 10 ILE A 168
VAL A 153
GLY A 155
VAL A 131
LEU A 331
 None
 1.29A 3em0A-5w8oA:
undetectable		 3em0A-5w8oA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		5 / 12 THR A 281
THR A 284
LEU A 103
ILE A  33
HIS A  58
 None
 1.37A 3gwxB-5w8oA:
undetectable		 3gwxB-5w8oA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_1
(CYTOCHROME P450 3A4)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		5 / 12 SER A 109
PHE A 353
ILE A  38
ALA A 137
GLY A 159
 None
 0.80A 3nxuA-5w8oA:
undetectable		 3nxuA-5w8oA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 6 GLY A 159
GLY A 156
TRP A  80
LEU A 354
 None
 0.79A 3o9mB-5w8oA:
13.1		 3o9mB-5w8oA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 ASP A  91
THR A  92
HIS A  65
LEU A 368
 None
 0.99A 3wg7A-5w8oA:
undetectable
3wg7C-5w8oA:
undetectable
3wg7P-5w8oA:
undetectable		 3wg7A-5w8oA:
20.38
3wg7C-5w8oA:
19.78
3wg7P-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 LEU A 368
ASP A  91
THR A  92
HIS A  65
 None
 1.04A 3wg7C-5w8oA:
undetectable
3wg7N-5w8oA:
undetectable
3wg7P-5w8oA:
1.7		 3wg7C-5w8oA:
19.78
3wg7N-5w8oA:
20.38
3wg7P-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA502_1
(CHITINASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 5 TRP A  80
GLY A 159
ALA A  59
PHE A 317
 None
 0.95A 3wqwA-5w8oA:
undetectable		 3wqwA-5w8oA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 ASP A  91
THR A  92
HIS A  65
LEU A 368
 None
 0.97A 3x2qA-5w8oA:
undetectable
3x2qC-5w8oA:
undetectable
3x2qP-5w8oA:
undetectable		 3x2qA-5w8oA:
20.38
3x2qC-5w8oA:
19.78
3x2qP-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 LEU A 368
ASP A  91
THR A  92
HIS A  65
 None
 0.99A 3x2qC-5w8oA:
undetectable
3x2qN-5w8oA:
undetectable
3x2qP-5w8oA:
undetectable		 3x2qC-5w8oA:
19.78
3x2qN-5w8oA:
20.38
3x2qP-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		5 / 12 LEU A 289
HIS A  58
GLY A 156
LEU A  60
GLY A  62
 None
 1.15A 4blvA-5w8oA:
undetectable		 4blvA-5w8oA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 6 PHE A 126
GLY A 105
LEU A 103
VAL A 102
 None
 0.94A 4dubA-5w8oA:
undetectable		 4dubA-5w8oA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		3 / 3 ARG A  42
TRP A  43
GLY A  15
 None
 0.87A 4e7cA-5w8oA:
undetectable		 4e7cA-5w8oA:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		5 / 9 VAL A  54
VAL A  55
VAL A  83
GLY A 177
ALA A 371
 None
 1.17A 4fwdA-5w8oA:
undetectable		 4fwdA-5w8oA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 6 ARG A 185
GLY A 183
GLU A 330
GLN A 194
 None
 1.31A 4g0vB-5w8oA:
undetectable		 4g0vB-5w8oA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 5 GLU A 239
SER A 346
ARG A 243
SER A 319
 None
 1.46A 4k17B-5w8oA:
1.0		 4k17B-5w8oA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA206_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 4 ALA A 137
ALA A 140
ALA A 141
ALA A 144
 None
 0.12A 4oadA-5w8oA:
undetectable		 4oadA-5w8oA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA208_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 4 ALA A 137
ALA A 140
ALA A 141
ALA A 144
 None
 0.10A 4oaeA-5w8oA:
undetectable		 4oaeA-5w8oA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_ACTA202_0
(RETINOL-BINDING
PROTEIN 2)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 6 TYR A 234
THR A 286
LEU A  60
GLN A 197
 None
 1.10A 4qztA-5w8oA:
undetectable		 4qztA-5w8oA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		5 / 12 VAL A  55
LEU A  57
LEU A 103
VAL A 135
LEU A 142
 None
 1.08A 4rrwC-5w8oA:
undetectable		 4rrwC-5w8oA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		5 / 12 VAL A  55
LEU A  57
LEU A 103
VAL A 135
LEU A 142
 None
 1.08A 4rrzC-5w8oA:
undetectable		 4rrzC-5w8oA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 4 ALA A 137
VAL A 102
GLY A 111
THR A 110
 None
 1.07A 4ubeA-5w8oA:
undetectable		 4ubeA-5w8oA:
26.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 ASP A  91
THR A  92
HIS A  65
LEU A 368
 None
 1.02A 5b1aA-5w8oA:
undetectable
5b1aC-5w8oA:
undetectable
5b1aP-5w8oA:
undetectable		 5b1aA-5w8oA:
20.38
5b1aC-5w8oA:
19.78
5b1aP-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 ASP A  91
THR A  92
HIS A  65
LEU A 368
 None
 0.96A 5b1bA-5w8oA:
undetectable
5b1bC-5w8oA:
1.6
5b1bP-5w8oA:
1.6		 5b1bA-5w8oA:
20.38
5b1bC-5w8oA:
19.78
5b1bP-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 ASP A  91
THR A  92
HIS A  65
LEU A 368
 None
 1.03A 5b3sA-5w8oA:
undetectable
5b3sC-5w8oA:
undetectable
5b3sP-5w8oA:
1.6		 5b3sA-5w8oA:
20.38
5b3sC-5w8oA:
19.78
5b3sP-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 TRP A  43
GLU A  41
HIS A  58
THR A 357
 None
 1.44A 5hqaA-5w8oA:
undetectable		 5hqaA-5w8oA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		5 / 9 ARG A 132
GLY A 300
ALA A 184
VAL A 301
GLU A 165
 None
 1.35A 5i3cA-5w8oA:
undetectable		 5i3cA-5w8oA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 LEU A 368
ASP A  91
THR A  92
HIS A  65
 None
 0.98A 5iy5C-5w8oA:
undetectable
5iy5N-5w8oA:
undetectable
5iy5P-5w8oA:
undetectable		 5iy5C-5w8oA:
19.41
5iy5N-5w8oA:
20.38
5iy5P-5w8oA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		3 / 3 GLY A  87
ASP A  91
ASN A  52
 None
 0.57A 5jglA-5w8oA:
undetectable		 5jglA-5w8oA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		3 / 3 GLY A 105
ASN A 101
ARG A 162
 None
 0.55A 5w7bD-5w8oA:
2.8		 5w7bD-5w8oA:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 ASP A  91
THR A  92
HIS A  65
LEU A 368
 None
 1.01A 5w97A-5w8oA:
undetectable
5w97C-5w8oA:
undetectable
5w97c-5w8oA:
undetectable		 5w97A-5w8oA:
20.38
5w97C-5w8oA:
19.78
5w97c-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 7 LEU A 368
ASP A  91
THR A  92
HIS A  65
 None
 1.03A 5w97C-5w8oA:
undetectable
5w97a-5w8oA:
undetectable
5w97c-5w8oA:
undetectable		 5w97C-5w8oA:
19.78
5w97a-5w8oA:
20.38
5w97c-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 ASP A  91
THR A  92
HIS A  65
LEU A 368
 None
 0.94A 5wauA-5w8oA:
undetectable
5wauC-5w8oA:
undetectable
5wauc-5w8oA:
undetectable		 5wauA-5w8oA:
20.38
5wauC-5w8oA:
19.78
5wauc-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 7 LEU A 368
ASP A  91
THR A  92
HIS A  65
 None
 0.91A 5wauC-5w8oA:
1.5
5waua-5w8oA:
undetectable
5wauc-5w8oA:
1.5		 5wauC-5w8oA:
19.78
5waua-5w8oA:
20.38
5wauc-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 ASP A  91
THR A  92
HIS A  65
LEU A 368
 None
 0.96A 5x19A-5w8oA:
undetectable
5x19C-5w8oA:
undetectable
5x19P-5w8oA:
1.6		 5x19A-5w8oA:
20.38
5x19C-5w8oA:
19.78
5x19P-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 7 ASP A  91
THR A  92
HIS A  65
LEU A 368
 None
 0.94A 5x1bA-5w8oA:
undetectable
5x1bC-5w8oA:
1.6
5x1bP-5w8oA:
undetectable		 5x1bA-5w8oA:
20.38
5x1bC-5w8oA:
19.78
5x1bP-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 7 ASP A  91
THR A  92
HIS A  65
LEU A 368
 None
 0.96A 5x1fA-5w8oA:
undetectable
5x1fC-5w8oA:
undetectable
5x1fP-5w8oA:
1.5		 5x1fA-5w8oA:
20.38
5x1fC-5w8oA:
19.78
5x1fP-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 ASP A  91
THR A  92
HIS A  65
LEU A 368
 None
 1.00A 5xdqA-5w8oA:
undetectable
5xdqC-5w8oA:
undetectable
5xdqP-5w8oA:
undetectable		 5xdqA-5w8oA:
20.38
5xdqC-5w8oA:
19.78
5xdqP-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 LEU A 368
ASP A  91
THR A  92
HIS A  65
 None
 1.00A 5xdqC-5w8oA:
undetectable
5xdqN-5w8oA:
undetectable
5xdqP-5w8oA:
undetectable		 5xdqC-5w8oA:
19.78
5xdqN-5w8oA:
20.38
5xdqP-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 LEU A 368
ASP A  91
THR A  92
HIS A  65
 None
 0.99A 5xdxC-5w8oA:
undetectable
5xdxN-5w8oA:
undetectable
5xdxP-5w8oA:
undetectable		 5xdxC-5w8oA:
19.41
5xdxN-5w8oA:
20.38
5xdxP-5w8oA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 ASP A  91
THR A  92
HIS A  65
LEU A 368
 None
 1.00A 5z84A-5w8oA:
undetectable
5z84C-5w8oA:
undetectable
5z84P-5w8oA:
undetectable		 5z84A-5w8oA:
20.38
5z84C-5w8oA:
19.78
5z84P-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 7 LEU A 368
ASP A  91
THR A  92
HIS A  65
 None
 1.00A 5z84C-5w8oA:
undetectable
5z84N-5w8oA:
undetectable
5z84P-5w8oA:
undetectable		 5z84C-5w8oA:
19.78
5z84N-5w8oA:
20.38
5z84P-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 7 LEU A 368
ASP A  91
THR A  92
HIS A  65
 None
 1.01A 5z85C-5w8oA:
undetectable
5z85N-5w8oA:
undetectable
5z85P-5w8oA:
undetectable		 5z85C-5w8oA:
19.78
5z85N-5w8oA:
20.38
5z85P-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 ASP A  91
THR A  92
HIS A  65
LEU A 368
 None
 1.00A 5z86A-5w8oA:
undetectable
5z86C-5w8oA:
undetectable
5z86P-5w8oA:
undetectable		 5z86A-5w8oA:
20.38
5z86C-5w8oA:
19.78
5z86P-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 LEU A 368
ASP A  91
THR A  92
HIS A  65
 None
 1.02A 5z86C-5w8oA:
undetectable
5z86N-5w8oA:
undetectable
5z86P-5w8oA:
undetectable		 5z86C-5w8oA:
19.78
5z86N-5w8oA:
20.38
5z86P-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 ASP A  91
THR A  92
HIS A  65
LEU A 368
 None
 1.02A 5zcoA-5w8oA:
undetectable
5zcoC-5w8oA:
undetectable
5zcoP-5w8oA:
undetectable		 5zcoA-5w8oA:
20.38
5zcoC-5w8oA:
19.78
5zcoP-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 LEU A 368
ASP A  91
THR A  92
HIS A  65
 None
 1.00A 5zcoC-5w8oA:
undetectable
5zcoN-5w8oA:
undetectable
5zcoP-5w8oA:
undetectable		 5zcoC-5w8oA:
19.78
5zcoN-5w8oA:
20.38
5zcoP-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 ASP A  91
THR A  92
HIS A  65
LEU A 368
 None
 1.04A 5zcpA-5w8oA:
undetectable
5zcpC-5w8oA:
undetectable
5zcpP-5w8oA:
undetectable		 5zcpA-5w8oA:
20.38
5zcpC-5w8oA:
19.78
5zcpP-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 LEU A 368
ASP A  91
THR A  92
HIS A  65
 None
 1.02A 5zcpC-5w8oA:
undetectable
5zcpN-5w8oA:
undetectable
5zcpP-5w8oA:
undetectable		 5zcpC-5w8oA:
19.78
5zcpN-5w8oA:
20.38
5zcpP-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 ASP A  91
THR A  92
HIS A  65
LEU A 368
 None
 1.02A 5zcqA-5w8oA:
undetectable
5zcqC-5w8oA:
1.7
5zcqP-5w8oA:
undetectable		 5zcqA-5w8oA:
20.38
5zcqC-5w8oA:
19.78
5zcqP-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSJ_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		5 / 10 LEU A 164
VAL A 312
VAL A 153
GLY A 177
LEU A 331
 None
 1.12A 6bsjA-5w8oA:
undetectable		 6bsjA-5w8oA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		5 / 12 ASP A  51
SER A 372
ALA A 151
ALA A 152
VAL A 153
 None
 1.06A 6c2mC-5w8oA:
undetectable		 6c2mC-5w8oA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_1
(STIE PROTEIN)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 5 THR A 130
ARG A 296
GLN A 194
ASP A 320
 None
 1.36A 6ecxA-5w8oA:
undetectable		 6ecxA-5w8oA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 8 LEU A 368
ASP A  91
THR A  92
HIS A  65
 None
 0.98A 6nknC-5w8oA:
undetectable
6nknN-5w8oA:
undetectable
6nknP-5w8oA:
undetectable		 6nknC-5w8oA:
19.78
6nknN-5w8oA:
20.38
6nknP-5w8oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5w8o HOMOSERINE
O-ACETYLTRANSFERASE
(Mycolicibacteriu
m
hassiacum) 		4 / 7 ASP A  91
THR A  92
HIS A  65
LEU A 368
 None
 0.94A 6nmfA-5w8oA:
undetectable
6nmfC-5w8oA:
undetectable
6nmfP-5w8oA:
undetectable		 6nmfA-5w8oA:
20.38
6nmfC-5w8oA:
19.78
6nmfP-5w8oA:
19.78