SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5w8p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		4 / 6 PHE A 284
ALA A 286
GLY A 287
TYR A 289
 None
 1.15A 1l5qB-5w8pA:
undetectable		 1l5qB-5w8pA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA1_1
(CES1 PROTEIN)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		6 / 12 GLY A 162
GLY A 163
LEU A 167
LEU A 296
LEU A 334
HIS A 357
 None
 1.26A 1ya4A-5w8pA:
12.5		 1ya4A-5w8pA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		5 / 12 LEU A 183
VAL A 320
CYH A 345
GLU A 369
LEU A 370
 None
 1.22A 2bxfA-5w8pA:
undetectable		 2bxfA-5w8pA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		5 / 12 LEU A 183
VAL A 320
CYH A 345
GLU A 369
LEU A 370
 None
 1.23A 2bxfB-5w8pA:
undetectable		 2bxfB-5w8pA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_1
(PROTEASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		5 / 12 ARG A 238
ASP A 327
VAL A 351
GLY A 159
ILE A 324
 None
 0.92A 2r5pA-5w8pA:
undetectable		 2r5pA-5w8pA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_1
(PROTEASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		5 / 12 ARG A 238
ASP A 327
VAL A 351
GLY A 159
ILE A 324
 None
 0.92A 2r5pC-5w8pA:
undetectable		 2r5pC-5w8pA:
14.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_A_CSCA1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		5 / 11 ARG A 230
TYR A 237
HIS A 357
ASP A 358
PHE A 360
 None
 0.70A 2vavA-5w8pA:
46.2		 2vavA-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_A_CSCA1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		6 / 11 LEU A  63
THR A  64
ARG A 230
TYR A 237
ARG A 246
HIS A 357
 None
 0.75A 2vavA-5w8pA:
46.2		 2vavA-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_A_CSCA1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		6 / 11 LEU A  63
THR A  64
ARG A 230
TYR A 237
HIS A 357
PHE A 360
 None
 0.55A 2vavA-5w8pA:
46.2		 2vavA-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_B_CSCB1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
ARG A 246
GLN A 276
HIS A 357
 None
 0.88A 2vavB-5w8pA:
46.1		 2vavB-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_B_CSCB1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
GLN A 276
HIS A 357
PHE A 360
 None
 0.72A 2vavB-5w8pA:
46.1		 2vavB-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_B_CSCB1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		5 / 12 TYR A 237
GLN A 276
HIS A 357
ASP A 358
PHE A 360
 None
 0.78A 2vavB-5w8pA:
46.1		 2vavB-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_C_CSCC1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		8 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
ARG A 246
TYR A 272
GLN A 276
HIS A 357
 None
 0.93A 2vavC-5w8pA:
46.1		 2vavC-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_C_CSCC1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		8 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
TYR A 272
GLN A 276
HIS A 357
PHE A 360
 None
 0.74A 2vavC-5w8pA:
46.1		 2vavC-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_D_CSCD1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		8 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
ARG A 246
TYR A 272
GLN A 276
HIS A 357
 None
 0.92A 2vavD-5w8pA:
46.2		 2vavD-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_D_CSCD1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		8 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
TYR A 272
GLN A 276
HIS A 357
PHE A 360
 None
 0.74A 2vavD-5w8pA:
46.2		 2vavD-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_E_CSCE1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 ARG A 230
TYR A 237
TYR A 272
GLN A 276
HIS A 357
ASP A 358
PHE A 360
 None
 0.79A 2vavE-5w8pA:
46.0		 2vavE-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_E_CSCE1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 THR A  64
ARG A 230
TYR A 237
ARG A 246
TYR A 272
GLN A 276
HIS A 357
 None
 0.98A 2vavE-5w8pA:
46.0		 2vavE-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_E_CSCE1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 THR A  64
ARG A 230
TYR A 237
TYR A 272
GLN A 276
HIS A 357
PHE A 360
 None
 0.76A 2vavE-5w8pA:
46.0		 2vavE-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_F_CSCF1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		6 / 12 ARG A 230
TYR A 237
TYR A 272
GLN A 276
ASP A 358
PHE A 360
 None
 0.82A 2vavF-5w8pA:
46.1		 2vavF-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_F_CSCF1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		6 / 12 THR A  64
ARG A 230
TYR A 237
ARG A 246
TYR A 272
GLN A 276
 None
 1.05A 2vavF-5w8pA:
46.1		 2vavF-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_F_CSCF1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		6 / 12 THR A  64
ARG A 230
TYR A 237
TYR A 272
GLN A 276
PHE A 360
 None
 0.85A 2vavF-5w8pA:
46.1		 2vavF-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_G_CSCG1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 ARG A 230
TYR A 237
TYR A 272
GLN A 276
HIS A 357
ASP A 358
PHE A 360
 None
 0.77A 2vavG-5w8pA:
46.2		 2vavG-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_G_CSCG1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 THR A  64
ARG A 230
TYR A 237
ARG A 246
TYR A 272
GLN A 276
HIS A 357
 None
 0.99A 2vavG-5w8pA:
46.2		 2vavG-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_G_CSCG1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 THR A  64
ARG A 230
TYR A 237
TYR A 272
GLN A 276
HIS A 357
PHE A 360
 None
 0.79A 2vavG-5w8pA:
46.2		 2vavG-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
ARG A 246
TYR A 272
HIS A 357
 None
 0.86A 2vavH-5w8pA:
46.2		 2vavH-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_I_CSCI1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
ARG A 246
GLN A 276
HIS A 357
 None
 0.88A 2vavI-5w8pA:
46.1		 2vavI-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_I_CSCI1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
GLN A 276
HIS A 357
PHE A 360
 None
 0.72A 2vavI-5w8pA:
46.1		 2vavI-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_I_CSCI1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		5 / 12 TYR A 237
GLN A 276
HIS A 357
ASP A 358
PHE A 360
 None
 0.77A 2vavI-5w8pA:
46.1		 2vavI-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
ARG A 246
TYR A 272
GLN A 276
 None
 0.96A 2vavJ-5w8pA:
45.9		 2vavJ-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
TYR A 272
GLN A 276
PHE A 360
 None
 0.78A 2vavJ-5w8pA:
45.9		 2vavJ-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		5 / 12 TYR A 237
TYR A 272
GLN A 276
ASP A 358
PHE A 360
 None
 0.82A 2vavJ-5w8pA:
45.9		 2vavJ-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
ARG A 246
TYR A 272
GLN A 276
 None
 0.95A 2vavK-5w8pA:
45.7		 2vavK-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
TYR A 272
GLN A 276
PHE A 360
 None
 0.79A 2vavK-5w8pA:
45.7		 2vavK-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 THR A  64
ARG A 230
TYR A 237
ARG A 246
TYR A 272
GLN A 276
HIS A 357
 None
 0.98A 2vavL-5w8pA:
46.0		 2vavL-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 THR A  64
ARG A 230
TYR A 237
TYR A 272
GLN A 276
HIS A 357
PHE A 360
 None
 0.80A 2vavL-5w8pA:
46.0		 2vavL-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		6 / 12 TYR A 237
TYR A 272
GLN A 276
HIS A 357
ASP A 358
PHE A 360
 None
 0.79A 2vavL-5w8pA:
46.0		 2vavL-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_A_CSCA1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		8 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
ARG A 246
TYR A 272
GLN A 276
HIS A 357
 None
 1.00A 2vaxA-5w8pA:
46.1		 2vaxA-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_A_CSCA1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		8 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
TYR A 272
GLN A 276
HIS A 357
PHE A 360
 None
 0.86A 2vaxA-5w8pA:
46.1		 2vaxA-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_B_CSCB1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		8 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
TYR A 272
GLN A 276
HIS A 357
PHE A 360
 None
 0.86A 2vaxB-5w8pA:
46.2		 2vaxB-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_C_CSCC1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 THR A  64
ARG A 230
TYR A 237
ARG A 246
TYR A 272
GLN A 276
HIS A 357
 None
 1.06A 2vaxC-5w8pA:
46.1		 2vaxC-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_C_CSCC1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 THR A  64
ARG A 230
TYR A 237
TYR A 272
GLN A 276
HIS A 357
PHE A 360
 None
 0.93A 2vaxC-5w8pA:
46.1		 2vaxC-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_D_CSCD1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		8 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
TYR A 272
GLN A 276
HIS A 357
PHE A 360
 None
 0.92A 2vaxD-5w8pA:
46.2		 2vaxD-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_E_CSCE1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		8 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
ARG A 246
TYR A 272
GLN A 276
HIS A 357
 None
 0.99A 2vaxE-5w8pA:
46.0		 2vaxE-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_E_CSCE1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		8 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
TYR A 272
GLN A 276
HIS A 357
PHE A 360
 None
 0.86A 2vaxE-5w8pA:
46.0		 2vaxE-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_F_CSCF1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
ARG A 246
GLN A 276
HIS A 357
 None
 0.92A 2vaxF-5w8pA:
46.3		 2vaxF-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_F_CSCF1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
ARG A 246
TYR A 272
HIS A 357
 None
 0.87A 2vaxF-5w8pA:
46.3		 2vaxF-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_F_CSCF1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
GLN A 276
HIS A 357
PHE A 360
 None
 0.83A 2vaxF-5w8pA:
46.3		 2vaxF-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_F_CSCF1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
TYR A 272
HIS A 357
PHE A 360
 None
 0.71A 2vaxF-5w8pA:
46.3		 2vaxF-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_G_CSCG1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
ARG A 246
GLN A 276
HIS A 357
 None
 0.97A 2vaxG-5w8pA:
46.3		 2vaxG-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_G_CSCG1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
GLN A 276
HIS A 357
PHE A 360
 None
 0.86A 2vaxG-5w8pA:
46.3		 2vaxG-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		8 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
ARG A 246
TYR A 272
GLN A 276
HIS A 357
 None
 0.83A 2vaxH-5w8pA:
46.4		 2vaxH-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		8 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
TYR A 272
GLN A 276
HIS A 357
PHE A 360
 None
 0.68A 2vaxH-5w8pA:
46.4		 2vaxH-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_I_CSCI1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		8 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
TYR A 272
GLN A 276
HIS A 357
PHE A 360
 None
 0.89A 2vaxI-5w8pA:
46.2		 2vaxI-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		8 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
ARG A 246
TYR A 272
GLN A 276
HIS A 357
 None
 0.99A 2vaxJ-5w8pA:
46.1		 2vaxJ-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		8 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
TYR A 272
GLN A 276
HIS A 357
PHE A 360
 None
 0.87A 2vaxJ-5w8pA:
46.1		 2vaxJ-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 LEU A  63
ARG A 230
TYR A 237
ARG A 246
TYR A 272
GLN A 276
HIS A 357
 None
 1.07A 2vaxK-5w8pA:
46.0		 2vaxK-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 LEU A  63
ARG A 230
TYR A 237
TYR A 272
GLN A 276
HIS A 357
PHE A 360
 None
 0.90A 2vaxK-5w8pA:
46.0		 2vaxK-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
ARG A 246
TYR A 272
HIS A 357
 None
 0.87A 2vaxK-5w8pA:
46.0		 2vaxK-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		7 / 12 LEU A  63
THR A  64
ARG A 230
TYR A 237
TYR A 272
HIS A 357
PHE A 360
 None
 0.71A 2vaxK-5w8pA:
46.0		 2vaxK-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		6 / 12 THR A  64
ARG A 230
TYR A 237
ARG A 246
GLN A 276
HIS A 357
 None
 0.94A 2vaxL-5w8pA:
46.2		 2vaxL-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		6 / 12 THR A  64
ARG A 230
TYR A 237
ARG A 246
TYR A 272
HIS A 357
 None
 0.86A 2vaxL-5w8pA:
46.2		 2vaxL-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		6 / 12 THR A  64
ARG A 230
TYR A 237
GLN A 276
HIS A 357
PHE A 360
 None
 0.83A 2vaxL-5w8pA:
46.2		 2vaxL-5w8pA:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		6 / 12 THR A  64
ARG A 230
TYR A 237
TYR A 272
HIS A 357
PHE A 360
 None
 0.67A 2vaxL-5w8pA:
46.2		 2vaxL-5w8pA:
32.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		4 / 5 PHE A 284
ALA A 286
GLY A 287
TYR A 289
 None
 1.20A 3bcrA-5w8pA:
2.5		 3bcrA-5w8pA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		4 / 6 PHE A 284
ALA A 286
GLY A 287
TYR A 289
 None
 1.15A 3dd1A-5w8pA:
2.7		 3dd1A-5w8pA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		4 / 6 PHE A 284
ALA A 286
GLY A 287
TYR A 289
 None
 1.15A 3ddsA-5w8pA:
undetectable		 3ddsA-5w8pA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		4 / 6 PHE A 284
ALA A 286
GLY A 287
TYR A 289
 None
 1.15A 3ddsB-5w8pA:
undetectable		 3ddsB-5w8pA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		4 / 6 PHE A 284
ALA A 286
GLY A 287
TYR A 289
 None
 1.15A 3ddwA-5w8pA:
undetectable		 3ddwA-5w8pA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		4 / 6 GLY A 162
GLY A 159
TRP A  83
LEU A 361
 None
 0.74A 3o9mB-5w8pA:
12.8		 3o9mB-5w8pA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		5 / 12 GLY A 163
ARG A 238
GLY A 322
ALA A 184
ALA A 359
 None
 0.94A 3sudA-5w8pA:
undetectable		 3sudA-5w8pA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		5 / 12 GLY A 163
ARG A 238
GLY A 322
ALA A 184
ALA A 359
 None
 0.86A 3sudC-5w8pA:
undetectable		 3sudC-5w8pA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		5 / 12 GLY A 163
GLY A 322
ALA A 184
ALA A 359
ASP A 358
 None
 0.93A 3sudD-5w8pA:
undetectable		 3sudD-5w8pA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		4 / 8 LEU A 167
VAL A 319
VAL A 156
LEU A 338
 None
 1.07A 3v81C-5w8pA:
undetectable		 3v81C-5w8pA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_1
(PROTEASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		5 / 9 ARG A 238
ASP A 327
ALA A 184
VAL A 351
ILE A 324
 None
 1.28A 3wsjA-5w8pA:
undetectable		 3wsjA-5w8pA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_1
(ASPARTYL PROTEASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		5 / 10 ARG A 238
ASP A 327
VAL A 351
GLY A 159
ILE A 324
 None
 1.07A 4dqcA-5w8pA:
undetectable		 4dqcA-5w8pA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_2
(PROTEASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		5 / 10 ARG A 238
ASP A 327
VAL A 351
GLY A 159
ILE A 324
 None
 1.06A 4njuB-5w8pA:
undetectable		 4njuB-5w8pA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_2
(PROTEASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		5 / 10 ARG A 238
ASP A 327
VAL A 351
GLY A 159
ILE A 324
 None
 1.05A 4njuD-5w8pA:
undetectable		 4njuD-5w8pA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		4 / 8 LEU A 167
VAL A 319
VAL A 156
LEU A 338
 None
 1.03A 4pwdC-5w8pA:
undetectable		 4pwdC-5w8pA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_ACTA202_0
(RETINOL-BINDING
PROTEIN 2)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		4 / 6 TYR A 237
THR A 293
LEU A  63
GLN A 200
 None
 1.14A 4qztA-5w8pA:
undetectable		 4qztA-5w8pA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		4 / 4 ALA A 140
VAL A 105
GLY A 114
THR A 113
 None
None
GOL  A 407 ( 4.4A)
None
 1.06A 4ubeA-5w8pA:
undetectable		 4ubeA-5w8pA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_B_ACTB403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		3 / 3 ARG A  53
ASP A  54
ARG A  52
 PO4  A 406 (-2.9A)
None
None
 0.68A 4wq4B-5w8pA:
undetectable		 4wq4B-5w8pA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		5 / 11 GLY A 114
ALA A 140
ILE A  28
LEU A  30
ILE A 291
 GOL  A 407 ( 4.4A)
None
None
None
None
 0.96A 4xumB-5w8pA:
undetectable		 4xumB-5w8pA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		4 / 4 VAL A 142
ALA A 144
PHE A  58
THR A 103
 None
 1.21A 4z4fA-5w8pA:
2.2		 4z4fA-5w8pA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		4 / 4 VAL A 142
ALA A 144
PHE A  58
THR A 103
 None
 1.23A 4z4hA-5w8pA:
2.6		 4z4hA-5w8pA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		5 / 9 ARG A 135
GLY A 307
ALA A 187
VAL A 308
GLU A 168
 None
None
None
PO4  A 405 ( 4.5A)
None
 1.36A 5i3cA-5w8pA:
2.4		 5i3cA-5w8pA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		3 / 3 GLY A  90
ASP A  94
ASN A  55
 None
 0.62A 5jglA-5w8pA:
undetectable		 5jglA-5w8pA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN8_A_ACRA1016_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		4 / 5 ASP A 285
GLY A 126
PRO A 115
CYH A 109
 None
 1.47A 5nn8A-5w8pA:
undetectable		 5nn8A-5w8pA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW5_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		4 / 8 SER A  67
THR A 112
GLY A 111
ALA A  21
 None
None
GOL  A 407 (-3.5A)
None
 0.66A 5vw5A-5w8pA:
undetectable		 5vw5A-5w8pA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 5w8p HOMOSERINE
O-ACETYLTRANSFERASE
(Mycobacteroides
abscessus) 		3 / 3 GLY A 108
ASN A 104
ARG A 165
 GOL  A 407 (-4.7A)
GOL  A 407 ( 4.8A)
None
 0.61A 5w7bD-5w8pA:
3.4		 5w7bD-5w8pA:
12.65