SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5w93'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 5w93 BREAST CANCER
ANTI-ESTROGEN
RESISTANCE PROTEIN 1
(Mus
musculus) 		4 / 7 SER A 786
SER A 843
ALA A 847
PHE A 782
 None
 1.11A 1fxvA-5w93A:
undetectable
1fxvB-5w93A:
undetectable		 1fxvA-5w93A:
20.60
1fxvB-5w93A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_A_STRA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 5w93 BREAST CANCER
ANTI-ESTROGEN
RESISTANCE PROTEIN 1
(Mus
musculus) 		5 / 11 GLN A 754
ALA A 755
THR A 763
VAL A 766
LEU A 857
 None
 1.11A 4j6cA-5w93A:
undetectable		 4j6cA-5w93A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_B_STRB503_1
(CYTOCHROME P450
MONOOXYGENASE)		 5w93 BREAST CANCER
ANTI-ESTROGEN
RESISTANCE PROTEIN 1
(Mus
musculus) 		5 / 10 GLN A 754
ALA A 755
THR A 763
VAL A 766
LEU A 857
 None
 1.11A 4j6cB-5w93A:
undetectable		 4j6cB-5w93A:
16.03