SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wax'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 5wax -
(-) 		3 / 3 GLN A 295
TYR A  13
ARG A  28
 None
 0.95A 1gtbA-5waxA:
undetectable		 1gtbA-5waxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAK_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 5wax -
(-) 		5 / 12 GLN A 115
GLY A 142
ILE A  70
LEU A 139
GLY A  91
 None
GOL  A 502 ( 4.4A)
None
None
None
 0.93A 1uakA-5waxA:
undetectable		 1uakA-5waxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B2000_1
(P38A)		 5wax -
(-) 		5 / 10 ILE A 175
ILE A 249
ILE A 258
TRP A 193
VAL A 179
 None
 1.46A 3ohtA-5waxA:
6.1
3ohtB-5waxA:
5.9		 3ohtA-5waxA:
undetectable
3ohtB-5waxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 5wax -
(-) 		3 / 3 TYR A 174
THR A 198
GLU A 210
 None
 0.65A 4df3A-5waxA:
undetectable		 4df3A-5waxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 5wax -
(-) 		3 / 3 TYR A 174
THR A 198
GLU A 210
 None
 0.66A 4df3B-5waxA:
undetectable		 4df3B-5waxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5wax -
(-) 		5 / 12 LEU A 133
VAL A 120
ALA A 176
PHE A 113
THR A 198
 None
 1.44A 4iaqA-5waxA:
2.8		 4iaqA-5waxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5wax -
(-) 		5 / 12 LEU A 133
VAL A 120
ALA A 176
PHE A 113
THR A 198
 None
 1.42A 4iarA-5waxA:
2.8		 4iarA-5waxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5wax -
(-) 		5 / 9 ILE A 238
GLU A 106
LEU A 116
LEU A 245
ILE A 263
 None
 1.19A 4r38C-5waxA:
undetectable		 4r38C-5waxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 5wax -
(-) 		5 / 12 LEU A 199
ILE A 263
GLU A 106
LEU A 203
SER A 239
 None
 1.21A 4r88A-5waxA:
undetectable		 4r88A-5waxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 5wax -
(-) 		5 / 12 LEU A 199
ILE A 263
GLU A 106
LEU A 203
SER A 239
 None
 1.18A 4r88B-5waxA:
undetectable		 4r88B-5waxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 5wax -
(-) 		5 / 12 LEU A 199
ILE A 263
GLU A 106
LEU A 203
SER A 239
 None
 1.21A 4r88C-5waxA:
undetectable		 4r88C-5waxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 5wax -
(-) 		5 / 12 LEU A 199
ILE A 263
GLU A 106
LEU A 203
SER A 239
 None
 1.21A 4r88D-5waxA:
undetectable		 4r88D-5waxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 5wax -
(-) 		5 / 12 LEU A 199
ILE A 263
GLU A 106
LEU A 203
SER A 239
 None
 1.19A 4r88E-5waxA:
undetectable		 4r88E-5waxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 5wax -
(-) 		5 / 12 LEU A 199
ILE A 263
GLU A 106
LEU A 203
SER A 239
 None
 1.20A 4r88F-5waxA:
undetectable		 4r88F-5waxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 5wax -
(-) 		5 / 12 GLN A 115
GLY A 142
ILE A  70
LEU A 139
GLY A  91
 None
GOL  A 502 ( 4.4A)
None
None
None
 0.93A 5wyqB-5waxA:
undetectable		 5wyqB-5waxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_D_GLYD713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 5wax -
(-) 		3 / 3 ARG A 147
HIS A  66
ARG A  71
 GOL  A 502 ( 4.3A)
None
None
 1.15A 6dwdD-5waxA:
undetectable		 6dwdD-5waxA:
undetectable