SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wb9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WFH_B_P2EB301_1
(MAB FAB H FRAGMENT
MAB FAB L FRAGMENT)		 5wb9 N60P23 FAB HEAVY
CHAIN
(Homo
sapiens) 		5 / 12 PHE H  33
HIS H  35
VAL H  37
TRP H  50
TRP H 110
 None
 0.58A 3wfhA-5wb9H:
26.2
3wfhB-5wb9H:
19.1		 3wfhA-5wb9H:
23.19
3wfhB-5wb9H:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WHX_B_XPGB301_1
(MAB FAB H FRAGMENT
MAB FAB L FRAGMENT)		 5wb9 N60P23 FAB HEAVY
CHAIN
(Homo
sapiens) 		5 / 12 PHE H  33
HIS H  35
VAL H  37
TRP H  50
TRP H 110
 None
 0.61A 3whxA-5wb9H:
26.3
3whxB-5wb9H:
19.1		 3whxA-5wb9H:
23.19
3whxB-5wb9H:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_A_ML1A302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5wb9 N60P23 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 8 PHE H  29
ILE H  74
PHE H  33
GLY H  56
 None
 0.88A 4qogA-5wb9H:
undetectable
4qogB-5wb9H:
undetectable		 4qogA-5wb9H:
19.90
4qogB-5wb9H:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)		 5wb9 N60P23 FAB HEAVY
CHAIN
(Homo
sapiens) 		3 / 3 PRO H 192
SER H 194
SER H 195
 None
 0.65A 6bpyA-5wb9H:
undetectable		 6bpyA-5wb9H:
undetectable