SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wbg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 12 PRO A 481
THR A 175
GLY A 299
ILE A 356
LEU A 313
 None
None
HEM  A 501 ( 3.9A)
None
None
 1.04A 1r30A-5wbgA:
undetectable		 1r30A-5wbgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 12 PRO A 481
THR A 175
GLY A 299
ILE A 356
LEU A 313
 None
None
HEM  A 501 ( 3.9A)
None
None
 1.04A 1r30B-5wbgA:
undetectable		 1r30B-5wbgA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2BDM_A_TMIA501_1
(CYTOCHROME P450 2B4)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		4 / 7 LEU A 295
PHE A 296
GLY A 299
THR A 303
 HEM  A 501 ( 4.5A)
None
HEM  A 501 ( 3.9A)
HEM  A 501 ( 4.6A)
 0.65A 2bdmA-5wbgA:
39.9		 2bdmA-5wbgA:
86.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BJF_A_DXCA330_0
(CHOLOYLGLYCINE
HYDROLASE)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 12 PHE A 449
PHE A 450
ILE A 353
ILE A 356
THR A 303
 None
None
None
None
HEM  A 501 ( 4.6A)
 1.24A 2bjfA-5wbgA:
undetectable		 2bjfA-5wbgA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NNH_A_9CRA501_1
(CYTOCHROME P450 2C8)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 11 ARG A  98
GLY A  99
ILE A 114
ALA A 298
THR A 302
 HEM  A 501 (-2.8A)
None
9ZJ  A 502 ( 3.6A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
 0.76A 2nnhA-5wbgA:
51.7		 2nnhA-5wbgA:
61.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NNH_A_9CRA501_1
(CYTOCHROME P450 2C8)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		6 / 11 ARG A  98
ILE A 114
ALA A 298
THR A 302
VAL A 367
PRO A 368
 HEM  A 501 (-2.8A)
9ZJ  A 502 ( 3.6A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
9ZJ  A 502 ( 4.2A)
None
 0.64A 2nnhA-5wbgA:
51.7		 2nnhA-5wbgA:
61.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NNH_B_9CRB501_1
(CYTOCHROME P450 2C8)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 9 ARG A  98
ILE A 114
THR A 302
VAL A 367
PRO A 368
 HEM  A 501 (-2.8A)
9ZJ  A 502 ( 3.6A)
9ZJ  A 502 ( 3.9A)
9ZJ  A 502 ( 4.2A)
None
 0.53A 2nnhB-5wbgA:
44.6		 2nnhB-5wbgA:
61.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NNJ_A_225A501_1
(CYTOCHROME P450 2C8)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 10 ILE A 114
ALA A 298
THR A 302
VAL A 367
PRO A 368
 9ZJ  A 502 ( 3.6A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
9ZJ  A 502 ( 4.2A)
None
 0.65A 2nnjA-5wbgA:
52.5		 2nnjA-5wbgA:
61.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QM9_A_TDZA201_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 12 PHE A 377
VAL A 388
ALA A  87
THR A 394
ARG A 378
 None
 1.46A 2qm9A-5wbgA:
undetectable		 2qm9A-5wbgA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1413_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		4 / 6 HIS A 397
ALA A 425
THR A 423
PHE A 413
 None
 0.98A 2xfhA-5wbgA:
28.9		 2xfhA-5wbgA:
13.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E4E_A_4PZA501_1
(CYTOCHROME P450 2E1)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		3 / 3 ALA A 298
THR A 302
CYH A 436
 9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
HEM  A 501 (-2.0A)
 0.39A 3e4eA-5wbgA:
54.8		 3e4eA-5wbgA:
56.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E4E_B_4PZB501_1
(CYTOCHROME P450 2E1)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		3 / 3 ALA A 298
THR A 302
CYH A 436
 9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
HEM  A 501 (-2.0A)
 0.32A 3e4eB-5wbgA:
54.8		 3e4eB-5wbgA:
56.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		4 / 7 VAL A 324
TYR A 348
GLU A 355
PRO A 410
 None
 1.12A 3hs4A-5wbgA:
undetectable		 3hs4A-5wbgA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		3 / 3 ASN A 200
ASN A 237
GLU A 240
 None
 0.84A 3kpdB-5wbgA:
undetectable		 3kpdB-5wbgA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		7 / 11 ILE A 114
ILE A 209
SER A 210
ALA A 298
VAL A 367
VAL A 477
GLY A 478
 9ZJ  A 502 ( 3.6A)
9ZJ  A 502 ( 4.8A)
None
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 4.2A)
None
None
 0.77A 3kw4A-5wbgA:
58.4		 3kw4A-5wbgA:
86.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		7 / 11 ILE A 114
ILE A 209
SER A 210
THR A 302
VAL A 367
VAL A 477
GLY A 478
 9ZJ  A 502 ( 3.6A)
9ZJ  A 502 ( 4.8A)
None
9ZJ  A 502 ( 3.9A)
9ZJ  A 502 ( 4.2A)
None
None
 0.85A 3kw4A-5wbgA:
58.4		 3kw4A-5wbgA:
86.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ME6_A_CGEA501_1
(CYTOCHROME P450 2B4)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		9 / 10 VAL A 104
PHE A 108
PHE A 206
ILE A 209
PHE A 297
ALA A 298
THR A 302
VAL A 367
VAL A 477
 None
9ZJ  A 502 (-4.4A)
9ZJ  A 502 (-2.6A)
9ZJ  A 502 ( 4.8A)
9ZJ  A 502 ( 4.5A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
9ZJ  A 502 ( 4.2A)
None
 0.54A 3me6A-5wbgA:
59.1		 3me6A-5wbgA:
86.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ME6_A_CGEA501_1
(CYTOCHROME P450 2B4)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		7 / 10 VAL A 104
PHE A 115
PHE A 206
ILE A 209
PHE A 297
ALA A 298
THR A 302
 None
9ZJ  A 502 (-4.7A)
9ZJ  A 502 (-2.6A)
9ZJ  A 502 ( 4.8A)
9ZJ  A 502 ( 4.5A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
 1.46A 3me6A-5wbgA:
59.1		 3me6A-5wbgA:
86.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		8 / 8 PHE A 108
PHE A 206
ILE A 209
PHE A 297
ALA A 298
THR A 302
VAL A 367
VAL A 477
 9ZJ  A 502 (-4.4A)
9ZJ  A 502 (-2.6A)
9ZJ  A 502 ( 4.8A)
9ZJ  A 502 ( 4.5A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
9ZJ  A 502 ( 4.2A)
None
 0.66A 3me6B-5wbgA:
59.3		 3me6B-5wbgA:
86.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 8 PHE A 115
PHE A 206
ILE A 209
PHE A 297
ALA A 298
 9ZJ  A 502 (-4.7A)
9ZJ  A 502 (-2.6A)
9ZJ  A 502 ( 4.8A)
9ZJ  A 502 ( 4.5A)
9ZJ  A 502 ( 3.5A)
 1.19A 3me6B-5wbgA:
59.3		 3me6B-5wbgA:
86.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		9 / 9 VAL A 104
PHE A 108
PHE A 206
ILE A 209
PHE A 297
ALA A 298
THR A 302
VAL A 367
VAL A 477
 None
9ZJ  A 502 (-4.4A)
9ZJ  A 502 (-2.6A)
9ZJ  A 502 ( 4.8A)
9ZJ  A 502 ( 4.5A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
9ZJ  A 502 ( 4.2A)
None
 0.46A 3me6C-5wbgA:
59.1		 3me6C-5wbgA:
86.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		7 / 9 VAL A 104
PHE A 115
PHE A 206
ILE A 209
PHE A 297
ALA A 298
THR A 302
 None
9ZJ  A 502 (-4.7A)
9ZJ  A 502 (-2.6A)
9ZJ  A 502 ( 4.8A)
9ZJ  A 502 ( 4.5A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
 1.42A 3me6C-5wbgA:
59.1		 3me6C-5wbgA:
86.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		9 / 9 VAL A 104
PHE A 108
PHE A 206
ILE A 209
PHE A 297
ALA A 298
THR A 302
VAL A 367
VAL A 477
 None
9ZJ  A 502 (-4.4A)
9ZJ  A 502 (-2.6A)
9ZJ  A 502 ( 4.8A)
9ZJ  A 502 ( 4.5A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
9ZJ  A 502 ( 4.2A)
None
 0.62A 3me6D-5wbgA:
59.1		 3me6D-5wbgA:
86.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		7 / 9 VAL A 104
PHE A 115
PHE A 206
ILE A 209
PHE A 297
ALA A 298
THR A 302
 None
9ZJ  A 502 (-4.7A)
9ZJ  A 502 (-2.6A)
9ZJ  A 502 ( 4.8A)
9ZJ  A 502 ( 4.5A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
 1.47A 3me6D-5wbgA:
59.1		 3me6D-5wbgA:
86.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 10 PHE A 108
PHE A 115
PHE A 297
ALA A 298
THR A 302
 9ZJ  A 502 (-4.4A)
9ZJ  A 502 (-4.7A)
9ZJ  A 502 ( 4.5A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
 0.53A 3t3qA-5wbgA:
56.5		 3t3qA-5wbgA:
66.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 10 PHE A 108
PHE A 115
PHE A 297
ALA A 298
THR A 302
 9ZJ  A 502 (-4.4A)
9ZJ  A 502 (-4.7A)
9ZJ  A 502 ( 4.5A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
 0.51A 3t3qB-5wbgA:
56.4		 3t3qB-5wbgA:
66.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 10 PHE A 108
PHE A 115
PHE A 297
ALA A 298
THR A 302
 9ZJ  A 502 (-4.4A)
9ZJ  A 502 (-4.7A)
9ZJ  A 502 ( 4.5A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
 0.51A 3t3qC-5wbgA:
56.4		 3t3qC-5wbgA:
66.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 10 PHE A 108
PHE A 115
PHE A 297
ALA A 298
THR A 302
 9ZJ  A 502 (-4.4A)
9ZJ  A 502 (-4.7A)
9ZJ  A 502 ( 4.5A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
 0.54A 3t3qD-5wbgA:
56.6		 3t3qD-5wbgA:
66.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 10 PHE A 107
PHE A 108
PHE A 202
ASN A 242
ILE A 241
 None
9ZJ  A 502 (-4.4A)
None
None
None
 1.34A 3t3rD-5wbgA:
55.6		 3t3rD-5wbgA:
66.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3S_A_9PLA1_1
(CYTOCHROME P450 2A13)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 9 PHE A 108
PHE A 206
PHE A 297
ALA A 298
THR A 302
 9ZJ  A 502 (-4.4A)
9ZJ  A 502 (-2.6A)
9ZJ  A 502 ( 4.5A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
 0.71A 3t3sA-5wbgA:
56.2		 3t3sA-5wbgA:
65.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3S_A_9PLA1_1
(CYTOCHROME P450 2A13)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 9 PHE A 115
PHE A 206
PHE A 297
ALA A 298
THR A 302
 9ZJ  A 502 (-4.7A)
9ZJ  A 502 (-2.6A)
9ZJ  A 502 ( 4.5A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
 1.29A 3t3sA-5wbgA:
56.2		 3t3sA-5wbgA:
65.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3S_B_9PLB1_1
(CYTOCHROME P450 2A13)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		4 / 6 PHE A 108
PHE A 297
ALA A 298
THR A 302
 9ZJ  A 502 (-4.4A)
9ZJ  A 502 ( 4.5A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
 0.41A 3t3sB-5wbgA:
56.0		 3t3sB-5wbgA:
65.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		4 / 7 PHE A 297
ALA A 298
THR A 302
LEU A 363
 9ZJ  A 502 ( 4.5A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
HEM  A 501 (-4.3A)
 0.47A 3t3sC-5wbgA:
55.8		 3t3sC-5wbgA:
65.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		4 / 8 PHE A 108
PHE A 297
ALA A 298
THR A 302
 9ZJ  A 502 (-4.4A)
9ZJ  A 502 ( 4.5A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
 0.25A 3t3sE-5wbgA:
54.9		 3t3sE-5wbgA:
65.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		4 / 5 PHE A 108
PHE A 297
ALA A 298
THR A 302
 9ZJ  A 502 (-4.4A)
9ZJ  A 502 ( 4.5A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
 1.15A 3t3zC-5wbgA:
54.4		 3t3zC-5wbgA:
56.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		6 / 11 ILE A 101
ILE A 114
ILE A 209
ALA A 298
VAL A 367
PRO A 368
 9ZJ  A 502 (-4.5A)
9ZJ  A 502 ( 3.6A)
9ZJ  A 502 ( 4.8A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 4.2A)
None
 0.92A 3tmzA-5wbgA:
55.7		 3tmzA-5wbgA:
86.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		6 / 11 ILE A 101
ILE A 114
ILE A 209
THR A 302
VAL A 367
PRO A 368
 9ZJ  A 502 (-4.5A)
9ZJ  A 502 ( 3.6A)
9ZJ  A 502 ( 4.8A)
9ZJ  A 502 ( 3.9A)
9ZJ  A 502 ( 4.2A)
None
 0.99A 3tmzA-5wbgA:
55.7		 3tmzA-5wbgA:
86.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 11 ILE A 114
ALA A 298
VAL A 367
PRO A 368
VAL A 477
 9ZJ  A 502 ( 3.6A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 4.2A)
None
None
 0.86A 3tmzA-5wbgA:
55.7		 3tmzA-5wbgA:
86.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 11 ILE A 114
THR A 302
VAL A 367
PRO A 368
VAL A 477
 9ZJ  A 502 ( 3.6A)
9ZJ  A 502 ( 3.9A)
9ZJ  A 502 ( 4.2A)
None
None
 0.83A 3tmzA-5wbgA:
55.7		 3tmzA-5wbgA:
86.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TMZ_A_06XA504_1
(CYTOCHROME P450 2B4)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 9 ILE A 101
ILE A 209
GLN A 215
GLU A 218
GLU A 387
 9ZJ  A 502 (-4.5A)
9ZJ  A 502 ( 4.8A)
None
None
None
 0.90A 3tmzA-5wbgA:
55.7		 3tmzA-5wbgA:
86.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TMZ_A_06XA504_1
(CYTOCHROME P450 2B4)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 9 LEU A  52
ILE A 101
ILE A 209
GLN A 215
GLU A 218
 None
9ZJ  A 502 (-4.5A)
9ZJ  A 502 ( 4.8A)
None
None
 1.17A 3tmzA-5wbgA:
55.7		 3tmzA-5wbgA:
86.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TMZ_A_06XA504_1
(CYTOCHROME P450 2B4)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 9 LEU A  70
ILE A 101
ILE A 209
GLN A 215
GLU A 387
 None
9ZJ  A 502 (-4.5A)
9ZJ  A 502 ( 4.8A)
None
None
 0.86A 3tmzA-5wbgA:
55.7		 3tmzA-5wbgA:
86.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UA5_A_06XA502_1
(CYTOCHROME P450 2B6)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 11 ARG A  73
GLN A 215
GLU A 218
PRO A 368
GLU A 387
 None
 1.09A 3ua5A-5wbgA:
54.8		 3ua5A-5wbgA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UA5_A_06XA502_1
(CYTOCHROME P450 2B6)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 11 ARG A  73
GLN A 215
PRO A 368
GLU A 387
VAL A 477
 None
 1.20A 3ua5A-5wbgA:
54.8		 3ua5A-5wbgA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UA5_A_06XA502_1
(CYTOCHROME P450 2B6)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		6 / 11 ARG A  73
MET A 365
PRO A 368
GLU A 387
PHE A 389
VAL A 477
 None
 0.83A 3ua5A-5wbgA:
54.8		 3ua5A-5wbgA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UA5_A_06XA502_1
(CYTOCHROME P450 2B6)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 11 GLN A 215
GLU A 218
LEU A 219
PRO A 368
GLU A 387
 None
 1.07A 3ua5A-5wbgA:
54.8		 3ua5A-5wbgA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UA5_A_06XA502_1
(CYTOCHROME P450 2B6)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 11 GLN A 215
LEU A 219
PRO A 368
GLU A 387
VAL A 477
 None
 1.12A 3ua5A-5wbgA:
54.8		 3ua5A-5wbgA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UA5_A_06XA502_1
(CYTOCHROME P450 2B6)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 11 LEU A 219
PRO A 368
GLU A 387
PHE A 389
VAL A 477
 None
 1.03A 3ua5A-5wbgA:
54.8		 3ua5A-5wbgA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		4 / 7 ILE A 114
THR A 302
LEU A 363
VAL A 477
 9ZJ  A 502 ( 3.6A)
9ZJ  A 502 ( 3.9A)
HEM  A 501 (-4.3A)
None
 0.66A 3ua5B-5wbgA:
54.8		 3ua5B-5wbgA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UA5_B_06XB502_1
(CYTOCHROME P450 2B6)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		6 / 10 ARG A  73
GLN A 215
GLU A 218
LEU A 219
PRO A 368
GLU A 387
 None
 1.11A 3ua5B-5wbgA:
54.8		 3ua5B-5wbgA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UA5_B_06XB502_1
(CYTOCHROME P450 2B6)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		6 / 10 ARG A  73
GLN A 215
LEU A 219
PRO A 368
GLU A 387
VAL A 477
 None
 1.20A 3ua5B-5wbgA:
54.8		 3ua5B-5wbgA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UA5_B_06XB502_1
(CYTOCHROME P450 2B6)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		6 / 10 ARG A  73
LEU A 219
PRO A 368
GLU A 387
PHE A 389
VAL A 477
 None
 1.11A 3ua5B-5wbgA:
54.8		 3ua5B-5wbgA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UA5_B_06XB502_1
(CYTOCHROME P450 2B6)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 10 MET A 365
PRO A 368
GLU A 387
PHE A 389
VAL A 477
 None
 0.76A 3ua5B-5wbgA:
54.8		 3ua5B-5wbgA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		4 / 7 PHE A 115
PHE A 297
ALA A 298
THR A 302
 9ZJ  A 502 (-4.7A)
9ZJ  A 502 ( 4.5A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
 0.41A 4ejgA-5wbgA:
56.5		 4ejgA-5wbgA:
65.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 8 PHE A 115
PHE A 297
ALA A 298
THR A 302
LEU A 363
 9ZJ  A 502 (-4.7A)
9ZJ  A 502 ( 4.5A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
HEM  A 501 (-4.3A)
 0.60A 4ejgB-5wbgA:
56.4		 4ejgB-5wbgA:
65.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EJG_C_NCTC501_1
(CYTOCHROME P450 2A13)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		4 / 7 PHE A 108
PHE A 115
ALA A 298
LEU A 363
 9ZJ  A 502 (-4.4A)
9ZJ  A 502 (-4.7A)
9ZJ  A 502 ( 3.5A)
HEM  A 501 (-4.3A)
 0.46A 4ejgC-5wbgA:
56.5		 4ejgC-5wbgA:
65.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		4 / 6 PHE A 115
ALA A 298
THR A 302
LEU A 363
 9ZJ  A 502 (-4.7A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
HEM  A 501 (-4.3A)
 0.44A 4ejgD-5wbgA:
56.4		 4ejgD-5wbgA:
65.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4H1N_A_CGEA505_1
(CYTOCHROME P450 2B4)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		8 / 11 ILE A 101
ILE A 114
ILE A 209
LEU A 238
ALA A 298
THR A 302
VAL A 367
VAL A 477
 9ZJ  A 502 (-4.5A)
9ZJ  A 502 ( 3.6A)
9ZJ  A 502 ( 4.8A)
None
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
9ZJ  A 502 ( 4.2A)
None
 0.73A 4h1nA-5wbgA:
58.0		 4h1nA-5wbgA:
86.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		6 / 8 ILE A 101
ILE A 114
GLU A 218
ALA A 298
VAL A 367
PRO A 368
 9ZJ  A 502 (-4.5A)
9ZJ  A 502 ( 3.6A)
None
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 4.2A)
None
 0.70A 4jltA-5wbgA:
57.9		 4jltA-5wbgA:
86.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_2
(BLUE-LIGHT
PHOTORECEPTOR)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 9 LEU A 396
VAL A  81
ILE A  84
LEU A  88
GLY A 366
 None
None
None
None
HEM  A 501 ( 4.5A)
 0.98A 4kukA-5wbgA:
undetectable		 4kukA-5wbgA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		4 / 6 PHE A 311
MET A 459
ILE A 453
VAL A 324
 None
 1.13A 4mk4B-5wbgA:
undetectable		 4mk4B-5wbgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 12 ASP A 266
LEU A 269
LEU A 288
LEU A 264
ILE A 265
 None
 1.10A 4x1fA-5wbgA:
2.0		 4x1fA-5wbgA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		4 / 4 LEU A 431
ILE A 435
PRO A 428
LEU A 392
 None
 1.23A 5eb3A-5wbgA:
undetectable		 5eb3A-5wbgA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 12 LEU A 437
GLY A 299
ILE A 441
MET A 132
LEU A 199
 HEM  A 501 (-4.7A)
HEM  A 501 ( 3.9A)
HEM  A 501 ( 4.5A)
HEM  A 501 ( 4.7A)
None
 0.94A 5ycnA-5wbgA:
undetectable		 5ycnA-5wbgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AY4_A_TPFA506_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 5wbg CYTOCHROME P450 2B6
(Homo
sapiens) 		5 / 10 PHE A 297
ALA A 298
THR A 302
LEU A 363
CYH A 436
 9ZJ  A 502 ( 4.5A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
HEM  A 501 (-4.3A)
HEM  A 501 (-2.0A)
 0.76A 6ay4A-5wbgA:
31.7		 6ay4A-5wbgA:
14.25