SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wco'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O5Y_H_STRH249_1
(CHIMERIC ANTIBODY
FAB 1E9-DB3)		 5wco NS2
(Salmon
isavirus) 		4 / 7 GLY A  42
THR A  46
MET A  41
SER A   4
 None
 1.20A 2o5yH-5wcoA:
undetectable
2o5yL-5wcoA:
undetectable		 2o5yH-5wcoA:
19.41
2o5yL-5wcoA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7A_A_MXDA1002_1
(ANDROGEN RECEPTOR)		 5wco NS2
(Salmon
isavirus) 		3 / 3 GLU A 170
TRP A 125
LYS A 164
 None
 1.46A 4k7aA-5wcoA:
undetectable		 4k7aA-5wcoA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_A_IPHA101_0
(INSULIN)		 5wco NS2
(Salmon
isavirus) 		5 / 10 LEU A 146
HIS A 178
LEU A 180
ALA A 176
LEU A 192
 None
 1.19A 4p65A-5wcoA:
undetectable
4p65B-5wcoA:
undetectable
4p65F-5wcoA:
undetectable
4p65H-5wcoA:
undetectable		 4p65A-5wcoA:
5.88
4p65B-5wcoA:
10.19
4p65F-5wcoA:
10.19
4p65H-5wcoA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WAN_C_ACTC303_0
(BRANCHPOINT-BRIDGING
PROTEIN)		 5wco NS2
(Salmon
isavirus) 		3 / 3 ASP A 119
ARG A  15
PRO A  12
 None
 0.82A 4wanC-5wcoA:
undetectable		 4wanC-5wcoA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJY_A_BEZA304_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 5wco NS2
(Salmon
isavirus) 		3 / 3 MET A 156
GLU A 167
ARG A 153
 None
 1.06A 5tjyA-5wcoA:
undetectable		 5tjyA-5wcoA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 5wco NS2
(Salmon
isavirus) 		3 / 3 MET A 156
GLU A 167
ARG A 153
 None
 1.03A 5tjzA-5wcoA:
undetectable		 5tjzA-5wcoA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 5wco NS2
(Salmon
isavirus) 		4 / 6 LEU A 109
LYS A   1
GLU A   3
LEU A  44
 None
 1.12A 5xooA-5wcoA:
undetectable		 5xooA-5wcoA:
17.07