SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wd6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 5wd6 SHORT PALATE, LUNG
AND NASAL EPITHELIUM
CARCINOMA-ASSOCIATED
PROTEIN 2B
(Bos
taurus) 		5 / 11 GLN A 109
VAL A 110
PRO A 111
ILE A  60
ILE A  93
 None
 1.36A 3ganA-5wd6A:
undetectable		 3ganA-5wd6A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_A_QI9A602_0
(CYTOCHROME P450 2D6)		 5wd6 SHORT PALATE, LUNG
AND NASAL EPITHELIUM
CARCINOMA-ASSOCIATED
PROTEIN 2B
(Bos
taurus) 		5 / 9 LEU A  42
SER A 207
VAL A 133
VAL A 103
LEU A 148
 None
 1.28A 4wnvA-5wd6A:
undetectable		 4wnvA-5wd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 5wd6 SHORT PALATE, LUNG
AND NASAL EPITHELIUM
CARCINOMA-ASSOCIATED
PROTEIN 2B
(Bos
taurus) 		4 / 7 THR A 154
LEU A  89
VAL A 108
GLU A  81
 None
 1.03A 5tudA-5wd6A:
undetectable		 5tudA-5wd6A:
14.07