SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wd8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GM7_B_PNNB1577_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 5wd8 LEM22
(Legionella
pneumophila) 		4 / 8 SER A  63
SER A   7
ALA A   9
ILE A  58
 None
 0.99A 1gm7A-5wd8A:
undetectable
1gm7B-5wd8A:
undetectable		 1gm7A-5wd8A:
16.59
1gm7B-5wd8A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)		 5wd8 LEM22
(Legionella
pneumophila) 		3 / 3 HIS A  48
MET A  21
MET A  52
 None
 1.24A 2vj1A-5wd8A:
undetectable		 2vj1A-5wd8A:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 5wd8 LEM22
(Legionella
pneumophila) 		4 / 5 LEU A  14
LEU A  17
LEU A  76
SER A  75
 None
 0.96A 3vhuA-5wd8A:
undetectable		 3vhuA-5wd8A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIX_A_NIMA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5wd8 LEM22
(Legionella
pneumophila) 		4 / 4 LEU A  14
ALA A   9
ILE A  58
LYS A  70
 None
 1.28A 4eixA-5wd8A:
undetectable		 4eixA-5wd8A:
22.66