SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wdd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5wdd BCL-2-RELATED
OVARIAN KILLER
PROTEIN
(Gallus
gallus) 		4 / 6 PHE A 115
VAL A 158
LEU A 154
ALA A 111
 None
 0.80A 2e1qA-5wddA:
undetectable		 2e1qA-5wddA:
5.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5wdd BCL-2-RELATED
OVARIAN KILLER
PROTEIN
(Gallus
gallus) 		4 / 6 PHE A 115
VAL A 158
LEU A 154
ALA A 111
 None
 0.78A 2e1qC-5wddA:
undetectable		 2e1qC-5wddA:
5.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 5wdd BCL-2-RELATED
OVARIAN KILLER
PROTEIN
(Gallus
gallus) 		4 / 5 LEU A  34
ILE A 175
ILE A  70
ALA A  69
 None
 0.74A 2i2zA-5wddA:
1.5		 2i2zA-5wddA:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)		 5wdd BCL-2-RELATED
OVARIAN KILLER
PROTEIN
(Gallus
gallus) 		4 / 4 LEU A  34
ILE A 175
ILE A  70
ALA A  69
 None
 0.76A 2i30A-5wddA:
2.8		 2i30A-5wddA:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5wdd BCL-2-RELATED
OVARIAN KILLER
PROTEIN
(Gallus
gallus) 		4 / 7 PHE A 115
VAL A 158
LEU A 154
ALA A 111
 None
 0.83A 3uniA-5wddA:
undetectable		 3uniA-5wddA:
5.15