SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wde'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		 5wde KINESIN-LIKE PROTEIN
KIFC3
(Homo
sapiens) 		4 / 7 ARG A 665
ASP A 659
ASP A 565
TRP A 566
 None
 1.36A 1cebA-5wdeA:
undetectable		 1cebA-5wdeA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5wde KINESIN-LIKE PROTEIN
KIFC3
(Homo
sapiens) 		5 / 12 SER A 746
VAL A 452
ILE A 479
SER A 489
PHE A 471
 None
None
None
UNX  A 920 ( 4.4A)
None
 1.33A 2vdyA-5wdeA:
undetectable		 2vdyA-5wdeA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_A_CAMA423_0
(CYTOCHROME P450)		 5wde KINESIN-LIKE PROTEIN
KIFC3
(Homo
sapiens) 		5 / 10 THR A 739
THR A 726
LEU A 704
GLY A 705
VAL A 718
 None
 1.24A 3lxiA-5wdeA:
undetectable		 3lxiA-5wdeA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5wde KINESIN-LIKE PROTEIN
KIFC3
(Homo
sapiens) 		5 / 12 SER A 746
VAL A 452
ILE A 479
SER A 489
PHE A 471
 None
None
None
UNX  A 920 ( 4.4A)
None
 1.12A 4c49A-5wdeA:
undetectable		 4c49A-5wdeA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5wde KINESIN-LIKE PROTEIN
KIFC3
(Homo
sapiens) 		5 / 12 SER A 746
VAL A 452
ILE A 479
SER A 489
PHE A 471
 None
None
None
UNX  A 920 ( 4.4A)
None
 1.38A 4c49C-5wdeA:
undetectable		 4c49C-5wdeA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5wde KINESIN-LIKE PROTEIN
KIFC3
(Homo
sapiens) 		5 / 12 SER A 746
VAL A 452
ILE A 479
SER A 489
PHE A 471
 None
None
None
UNX  A 920 ( 4.4A)
None
 1.34A 4c49D-5wdeA:
undetectable		 4c49D-5wdeA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_A_CAMA424_0
(CYTOCHROME P450)		 5wde KINESIN-LIKE PROTEIN
KIFC3
(Homo
sapiens) 		5 / 9 THR A 739
THR A 726
LEU A 704
GLY A 705
VAL A 718
 None
 1.21A 4c9kA-5wdeA:
undetectable		 4c9kA-5wdeA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 5wde KINESIN-LIKE PROTEIN
KIFC3
(Homo
sapiens) 		5 / 9 THR A 739
THR A 726
LEU A 704
GLY A 705
VAL A 718
 None
 1.27A 4c9pA-5wdeA:
undetectable		 4c9pA-5wdeA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 5wde KINESIN-LIKE PROTEIN
KIFC3
(Homo
sapiens) 		4 / 5 CYH A 523
SER A 732
LEU A 606
LEU A 725
 None
UNX  A 932 ( 2.7A)
None
None
 1.24A 4n09D-5wdeA:
undetectable		 4n09D-5wdeA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 5wde KINESIN-LIKE PROTEIN
KIFC3
(Homo
sapiens) 		5 / 12 SER A 732
PHE A 525
LEU A 701
LEU A 675
VAL A 673
 UNX  A 932 ( 2.7A)
None
UNX  A 931 ( 4.6A)
UNX  A 931 ( 4.2A)
None
 1.08A 5tudA-5wdeA:
undetectable		 5tudA-5wdeA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 5wde KINESIN-LIKE PROTEIN
KIFC3
(Homo
sapiens) 		5 / 12 VAL A 452
VAL A 745
ASP A 472
PHE A 471
ASN A 467
 None
None
UNX  A 909 ( 3.7A)
None
None
 1.45A 6iblA-5wdeA:
undetectable		 6iblA-5wdeA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 5wde KINESIN-LIKE PROTEIN
KIFC3
(Homo
sapiens) 		5 / 12 VAL A 452
VAL A 745
ASP A 472
PHE A 471
ASN A 467
 None
None
UNX  A 909 ( 3.7A)
None
None
 1.36A 6iblB-5wdeA:
undetectable		 6iblB-5wdeA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_0
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 5wde KINESIN-LIKE PROTEIN
KIFC3
(Homo
sapiens) 		5 / 12 VAL A 452
VAL A 745
ASP A 472
PHE A 471
ASN A 467
 None
None
UNX  A 909 ( 3.7A)
None
None
 1.42A 6mxtA-5wdeA:
undetectable		 6mxtA-5wdeA:
22.80