SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wdi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_2
(ESTROGEN RECEPTOR)		 5wdi UBIQUITIN-ASSOCIATED
AND SH3
DOMAIN-CONTAINING
PROTEIN A
(Homo
sapiens) 		4 / 6 LEU A 584
LEU A 620
LEU A 532
LEU A 529
 None
 0.78A 1errA-5wdiA:
undetectable		 1errA-5wdiA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5wdi UBIQUITIN-ASSOCIATED
AND SH3
DOMAIN-CONTAINING
PROTEIN A
(Homo
sapiens) 		4 / 7 PHE A 547
ALA A 567
ILE A 511
ILE A 572
 None
 0.95A 1oniD-5wdiA:
undetectable
1oniF-5wdiA:
undetectable		 1oniD-5wdiA:
19.46
1oniF-5wdiA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)		 5wdi UBIQUITIN-ASSOCIATED
AND SH3
DOMAIN-CONTAINING
PROTEIN A
(Homo
sapiens) 		4 / 6 ARG A 564
THR A 566
ALA A 567
PRO A 604
 None
 1.15A 2ql8A-5wdiA:
undetectable
2ql8B-5wdiA:
undetectable		 2ql8A-5wdiA:
18.56
2ql8B-5wdiA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_B_J01B500_1
(ORF12)		 5wdi UBIQUITIN-ASSOCIATED
AND SH3
DOMAIN-CONTAINING
PROTEIN A
(Homo
sapiens) 		5 / 9 VAL A 582
ILE A 475
LEU A 620
GLY A 465
ALA A 464
 None
 0.98A 2xf3B-5wdiA:
undetectable		 2xf3B-5wdiA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_B_J01B500_1
(ORF12)		 5wdi UBIQUITIN-ASSOCIATED
AND SH3
DOMAIN-CONTAINING
PROTEIN A
(Homo
sapiens) 		5 / 9 VAL A 582
ILE A 475
LEU A 620
GLY A 465
ALA A 464
 None
 0.99A 2xfsB-5wdiA:
undetectable		 2xfsB-5wdiA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_B_J01B1436_1
(ORF12)		 5wdi UBIQUITIN-ASSOCIATED
AND SH3
DOMAIN-CONTAINING
PROTEIN A
(Homo
sapiens) 		5 / 9 VAL A 582
ILE A 475
LEU A 620
GLY A 465
ALA A 464
 None
 0.99A 2xh9B-5wdiA:
undetectable		 2xh9B-5wdiA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 5wdi UBIQUITIN-ASSOCIATED
AND SH3
DOMAIN-CONTAINING
PROTEIN A
(Homo
sapiens) 		4 / 6 ARG A 564
GLY A 510
LEU A 549
PRO A 482
 None
 0.90A 3bgdA-5wdiA:
undetectable		 3bgdA-5wdiA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_2
(FIV PROTEASE)		 5wdi UBIQUITIN-ASSOCIATED
AND SH3
DOMAIN-CONTAINING
PROTEIN A
(Homo
sapiens) 		5 / 10 LEU A 399
ILE A 505
VAL A 478
VAL A 582
LEU A 584
 None
 1.21A 3ogpB-5wdiA:
undetectable		 3ogpB-5wdiA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_G_CHDG401_0
(BILE SALT HYDROLASE)		 5wdi UBIQUITIN-ASSOCIATED
AND SH3
DOMAIN-CONTAINING
PROTEIN A
(Homo
sapiens) 		5 / 10 PHE A 447
LEU A 484
ALA A 483
LEU A 526
GLU A 556
 None
 1.25A 5y7pG-5wdiA:
undetectable		 5y7pG-5wdiA:
22.51