SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wdu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 12 LEU G 454
ASN G 283
GLY G 471
GLN G 258
VAL G 371
 None
 0.89A 1nhzA-5wduG:
undetectable		 1nhzA-5wduG:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1;
Human
immunodeficiency
virus
1) 		5 / 10 THR A 639
VAL G  38
VAL G  44
ASP A 632
VAL G  42
 None
 1.43A 1o76A-5wduA:
undetectable		 1o76A-5wduA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAK_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		6 / 12 GLY I 101
SER I  34
ILE I  33
VAL I  97
LEU I   4
GLY I  99
 None
 1.36A 1uakA-5wduI:
undetectable		 1uakA-5wduI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 VAL I 106
ARG I  61
VAL I  19
GLU I  83
 None
 1.17A 1zzrA-5wduI:
undetectable
1zzrB-5wduI:
undetectable		 1zzrA-5wduI:
11.97
1zzrB-5wduI:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 GLU I  83
VAL I 106
ARG I  61
VAL I  19
 None
 1.22A 1zzrA-5wduI:
undetectable
1zzrB-5wduI:
undetectable		 1zzrA-5wduI:
11.97
1zzrB-5wduI:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 VAL I 106
ARG I  61
VAL I  19
GLU I  83
 None
 1.19A 1zzuA-5wduI:
undetectable
1zzuB-5wduI:
undetectable		 1zzuA-5wduI:
11.97
1zzuB-5wduI:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 GLU I  83
VAL I 106
ARG I  61
VAL I  19
 None
 1.23A 1zzuA-5wduI:
undetectable
1zzuB-5wduI:
undetectable		 1zzuA-5wduI:
11.97
1zzuB-5wduI:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 12 LEU G 349
ILE G 272
PHE G 288
GLY G 451
LEU G 454
 None
 1.19A 2bxeB-5wduG:
undetectable		 2bxeB-5wduG:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1321_0
(CHLOROPEROXIDASE)		 5wdu BNAB NIH45-46 SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 5 LEU E  76
PHE E  60
VAL E  98
ALA E  19
 None
 1.04A 2cizA-5wduE:
undetectable		 2cizA-5wduE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA501_1
(CYTOCHROME P450 2C8)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 11 GLY A 527
ALA G 497
THR G  37
VAL G  42
PRO G  43
 None
 1.14A 2nnhA-5wduA:
undetectable		 2nnhA-5wduA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OLD_B_IPHB2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 5wdu BNAB NIH45-46 SCFV
HEAVY CHAIN
BNAB NIH45-46 SCFV
LIGHT CHAIN
(Homo
sapiens;
Homo
sapiens) 		4 / 7 TYR E  34
PRO E  42
TYR E  85
PRO D  45
 None
 0.73A 2oldA-5wduE:
17.1
2oldB-5wduE:
17.0		 2oldA-5wduE:
undetectable
2oldB-5wduE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 5wdu BNAB NIH45-46 SCFV
HEAVY CHAIN
BNAB NIH45-46 SCFV
LIGHT CHAIN
(Homo
sapiens;
Homo
sapiens) 		4 / 7 PRO D  45
TYR E  34
PRO E  42
TYR E  85
 None
 0.70A 2ombC-5wduD:
14.0
2ombD-5wduD:
14.1		 2ombC-5wduD:
undetectable
2ombD-5wduD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		4 / 7 THR G 290
PRO G 291
VAL G 292
GLU G 340
 None
NAG  G 652 (-4.5A)
None
None
 1.07A 2v2gA-5wduG:
undetectable
2v2gB-5wduG:
undetectable		 2v2gA-5wduG:
undetectable
2v2gB-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		4 / 7 THR G 290
PRO G 291
VAL G 292
GLU G 340
 None
NAG  G 652 (-4.5A)
None
None
 1.04A 2v2gA-5wduG:
undetectable
2v2gB-5wduG:
undetectable		 2v2gA-5wduG:
undetectable
2v2gB-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		4 / 7 THR G 290
PRO G 291
VAL G 292
GLU G 340
 None
NAG  G 652 (-4.5A)
None
None
 1.07A 2v2gC-5wduG:
undetectable
2v2gD-5wduG:
undetectable		 2v2gC-5wduG:
undetectable
2v2gD-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		4 / 7 THR G 290
PRO G 291
VAL G 292
GLU G 340
 None
NAG  G 652 (-4.5A)
None
None
 1.05A 2v2gC-5wduG:
undetectable
2v2gD-5wduG:
undetectable		 2v2gC-5wduG:
undetectable
2v2gD-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		4 / 7 THR G 290
PRO G 291
VAL G 292
GLU G 340
 None
NAG  G 652 (-4.5A)
None
None
 1.07A 2v41E-5wduG:
undetectable
2v41F-5wduG:
undetectable		 2v41E-5wduG:
undetectable
2v41F-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)		 5wdu BNAB NIH45-46 SCFV
LIGHT CHAIN
(Homo
sapiens) 		3 / 3 GLY E  29
TYR E  89
SER E  30
 NAG  G 633 ( 4.5A)
None
None
 0.78A 2xatA-5wduE:
undetectable		 2xatA-5wduE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 5wdu BNAB NIH45-46 SCFV
HEAVY CHAIN
(Homo
sapiens) 		3 / 3 ARG D  53
ASP D  76
ASN D  31
 None
 0.62A 2zzmA-5wduD:
undetectable		 2zzmA-5wduD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA2_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		3 / 3 LYS G 487
LYS G  46
VAL G 489
 None
 0.85A 3brfA-5wduG:
undetectable		 3brfA-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 VAL I 106
ARG I  61
VAL I  19
GLU I  83
 None
 1.17A 3dqrA-5wduI:
undetectable
3dqrB-5wduI:
undetectable		 3dqrA-5wduI:
11.91
3dqrB-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 GLU I  83
VAL I 106
ARG I  61
VAL I  19
 None
 1.21A 3dqrA-5wduI:
undetectable
3dqrB-5wduI:
undetectable		 3dqrA-5wduI:
11.91
3dqrB-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 5 PRO I  26
VAL I  27
THR I 102
GLY I 101
 None
 0.81A 3elzB-5wduI:
undetectable		 3elzB-5wduI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 VAL I 106
ARG I  61
VAL I  19
GLU I  83
 None
 1.18A 3jx2A-5wduI:
undetectable
3jx2B-5wduI:
undetectable		 3jx2A-5wduI:
11.91
3jx2B-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 GLU I  83
VAL I 106
ARG I  61
VAL I  19
 None
 1.17A 3jx2A-5wduI:
undetectable
3jx2B-5wduI:
undetectable		 3jx2A-5wduI:
11.91
3jx2B-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 VAL I 106
ARG I  61
VAL I  19
GLU I  83
 None
 1.19A 3jx3A-5wduI:
undetectable
3jx3B-5wduI:
undetectable		 3jx3A-5wduI:
11.91
3jx3B-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 GLU I  83
VAL I 106
ARG I  61
VAL I  19
 None
 1.17A 3jx3A-5wduI:
undetectable
3jx3B-5wduI:
undetectable		 3jx3A-5wduI:
11.91
3jx3B-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 GLU I  83
VAL I 106
ARG I  61
VAL I  19
 None
 1.17A 3jx4A-5wduI:
undetectable
3jx4B-5wduI:
undetectable		 3jx4A-5wduI:
11.91
3jx4B-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 VAL I 106
ARG I  61
VAL I  19
GLU I  83
 None
 1.15A 3jx5A-5wduI:
undetectable
3jx5B-5wduI:
undetectable		 3jx5A-5wduI:
11.91
3jx5B-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 GLU I  83
VAL I 106
ARG I  61
VAL I  19
 None
 1.14A 3jx5A-5wduI:
undetectable
3jx5B-5wduI:
undetectable		 3jx5A-5wduI:
11.91
3jx5B-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 VAL I 106
ARG I  61
VAL I  19
GLU I  83
 None
 1.12A 3jx6A-5wduI:
undetectable
3jx6B-5wduI:
undetectable		 3jx6A-5wduI:
11.91
3jx6B-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 GLU I  83
VAL I 106
ARG I  61
VAL I  19
 None
 1.16A 3jx6A-5wduI:
undetectable
3jx6B-5wduI:
undetectable		 3jx6A-5wduI:
11.91
3jx6B-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		3 / 3 ASP G 457
ASN G 280
SER G 365
 None
 0.97A 3lsfB-5wduG:
undetectable
3lsfE-5wduG:
undetectable		 3lsfB-5wduG:
undetectable
3lsfE-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 VAL I 106
ARG I  61
VAL I  19
GLU I  83
 None
 1.14A 3nljA-5wduI:
undetectable
3nljB-5wduI:
undetectable		 3nljA-5wduI:
11.91
3nljB-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 GLU I  83
VAL I 106
ARG I  61
VAL I  19
 None
 1.13A 3nljA-5wduI:
undetectable
3nljB-5wduI:
undetectable		 3nljA-5wduI:
11.91
3nljB-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 VAL I 106
ARG I  61
VAL I  19
GLU I  83
 None
 1.13A 3nlpA-5wduI:
undetectable
3nlpB-5wduI:
undetectable		 3nlpA-5wduI:
11.91
3nlpB-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 GLU I  83
VAL I 106
ARG I  61
VAL I  19
 None
 1.16A 3nlpA-5wduI:
undetectable
3nlpB-5wduI:
undetectable		 3nlpA-5wduI:
11.91
3nlpB-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 8 VAL I 106
ARG I  61
VAL I  19
GLU I  83
 None
 1.14A 3nlqA-5wduI:
undetectable
3nlqB-5wduI:
undetectable		 3nlqA-5wduI:
11.91
3nlqB-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 GLU I  83
VAL I 106
ARG I  61
VAL I  19
 None
 1.16A 3nlqA-5wduI:
undetectable
3nlqB-5wduI:
undetectable		 3nlqA-5wduI:
11.91
3nlqB-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 VAL I 106
ARG I  61
VAL I  19
GLU I  83
 None
 1.13A 3nlrA-5wduI:
undetectable
3nlrB-5wduI:
undetectable		 3nlrA-5wduI:
11.91
3nlrB-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 8 GLU I  83
VAL I 106
ARG I  61
VAL I  19
 None
 1.15A 3nlrA-5wduI:
undetectable
3nlrB-5wduI:
undetectable		 3nlrA-5wduI:
11.91
3nlrB-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5wdu BNAB NIH45-46 SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 8 VAL E  98
LEU E  13
LEU E  76
ILE E  20
 None
 0.92A 3u5kC-5wduE:
undetectable		 3u5kC-5wduE:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5wdu BNAB NIH45-46 SCFV
LIGHT CHAIN
(Homo
sapiens) 		3 / 3 SER E  28
GLY E  29
GLN E  88
 MAN  G 626 (-4.0A)
NAG  G 633 ( 4.5A)
None
 0.00A 3v4tH-5wduE:
undetectable		 3v4tH-5wduE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1;
Human
immunodeficiency
virus
1) 		4 / 5 LEU G  86
GLY A 524
THR A 536
VAL A 539
 None
 1.07A 3wrkD-5wduG:
undetectable		 3wrkD-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		4 / 4 ASN G 295
SER G 256
LEU G 261
THR G 297
 NAG  G 634 (-1.9A)
None
NAG  G 627 ( 4.8A)
NAG  G 641 (-3.4A)
 1.44A 4an2A-5wduG:
undetectable		 4an2A-5wduG:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 VAL I 106
ARG I  61
VAL I  19
GLU I  83
 None
 1.20A 4cx3A-5wduI:
undetectable
4cx3B-5wduI:
undetectable		 4cx3A-5wduI:
11.91
4cx3B-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 GLU I  83
VAL I 106
ARG I  61
VAL I  19
 None
 1.21A 4cx3A-5wduI:
undetectable
4cx3B-5wduI:
undetectable		 4cx3A-5wduI:
11.91
4cx3B-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 VAL I 106
ARG I  61
VAL I  19
GLU I  83
 None
 1.20A 4cx4A-5wduI:
undetectable
4cx4B-5wduI:
undetectable		 4cx4A-5wduI:
11.91
4cx4B-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 GLU I  83
VAL I 106
ARG I  61
VAL I  19
 None
 1.19A 4cx4A-5wduI:
undetectable
4cx4B-5wduI:
undetectable		 4cx4A-5wduI:
11.91
4cx4B-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 12 LEU G 285
LEU G 260
SER G 256
THR G 257
VAL G 101
 None
 1.06A 4f4dB-5wduG:
undetectable		 4f4dB-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 10 LEU G 261
ILE G 449
GLY G 451
PHE G 376
SER G 375
 NAG  G 627 ( 4.8A)
None
None
None
None
 0.94A 4fakA-5wduG:
undetectable		 4fakA-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5wdu BNAB NIH45-46 SCFV
LIGHT CHAIN
(Homo
sapiens) 		5 / 12 VAL E  98
ILE E  56
ILE E  21
ILE E  20
LEU E  13
 None
 0.99A 4iv0A-5wduE:
undetectable		 4iv0A-5wduE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		4 / 8 ILE G 309
ALA G 319
PRO G 124
VAL G 120
 None
 0.83A 4jltA-5wduG:
undetectable		 4jltA-5wduG:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		4 / 4 VAL G  89
THR G  90
GLU G  91
GLU G  92
 None
 1.36A 4l78A-5wduG:
undetectable		 4l78A-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		4 / 4 VAL G 242
THR G  90
GLU G  91
GLU G  92
 None
 1.37A 4l78A-5wduG:
undetectable		 4l78A-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		4 / 6 GLU A 654
GLN A 650
VAL G  36
THR G  37
 None
 1.20A 4lnxA-5wduA:
undetectable		 4lnxA-5wduA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5wdu BNAB NIH45-46 SCFV
LIGHT CHAIN
(Homo
sapiens) 		5 / 12 VAL E  98
ILE E  56
ILE E  21
ILE E  20
LEU E  13
 None
 0.98A 4mwzB-5wduE:
undetectable		 4mwzB-5wduE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P66_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 11 ILE G 215
ALA G  55
LEU G  52
LEU G 483
ILE G 251
 None
 0.97A 4p66A-5wduG:
undetectable		 4p66A-5wduG:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 5wdu BNAB NIH45-46 SCFV
HEAVY CHAIN
ENVELOPE
GLYCOPROTEIN GP160
(Homo
sapiens;
Human
immunodeficiency
virus
1) 		5 / 12 GLY D  55
VAL D  73
TYR D  74
LEU D  30
ASN G 425
 None
None
NAG  G 617 (-4.2A)
None
None
 1.16A 4pd5A-5wduD:
undetectable		 4pd5A-5wduD:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 5wdu BNAB NIH45-46 SCFV
HEAVY CHAIN
(Homo
sapiens) 		3 / 3 GLY D  42
PRO D  41
ALA D  88
 None
 0.54A 4qn9B-5wduD:
undetectable		 4qn9B-5wduD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UG5_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		3 / 3 ARG G 350
THR G 394
TRP G 395
 None
 1.27A 4ug5A-5wduG:
undetectable		 4ug5A-5wduG:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ5_B_ACTB404_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		3 / 3 TYR G 191
ARG G 178
LYS G 155
 None
NAG  G 606 (-4.2A)
NAG  G 606 (-3.3A)
 1.24A 4wq5B-5wduG:
undetectable		 4wq5B-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA409_0
(FAD:PROTEIN FMN
TRANSFERASE)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 5 VAL I  19
ILE I  21
VAL I 104
THR I 102
 None
 0.66A 4xdtA-5wduI:
undetectable		 4xdtA-5wduI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 11 SER G 388
THR G 387
SER G 375
GLU G 370
GLY G 366
 NAG  G 653 (-3.0A)
None
None
None
NAG  G 653 ( 4.6A)
 1.39A 4zjoD-5wduG:
undetectable		 4zjoD-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 GLU I  83
VAL I 106
ARG I  61
VAL I  19
 None
 1.11A 5addA-5wduI:
undetectable
5addB-5wduI:
undetectable		 5addA-5wduI:
11.91
5addB-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 GLU I  83
VAL I 106
ARG I  61
VAL I  19
 None
 1.02A 5adeA-5wduI:
undetectable
5adeB-5wduI:
undetectable		 5adeA-5wduI:
11.91
5adeB-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 5wdu BNAB NIH45-46 SCFV
LIGHT CHAIN
(Homo
sapiens) 		3 / 3 ASN E  70
SER E  22
ARG E  24
 None
 0.94A 5b2qA-5wduE:
undetectable		 5b2qA-5wduE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_1
(CYP51 VARIANT1)		 5wdu BNAB NIH45-46 SCFV
HEAVY CHAIN
BNAB NIH45-46 SCFV
LIGHT CHAIN
(Homo
sapiens) 		5 / 12 ALA D  60
TYR E  34
PHE E  92
GLY E  49
PHE D 104
 None
 1.20A 5fsaA-5wduD:
undetectable		 5fsaA-5wduD:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 VAL I 106
ARG I  61
VAL I  19
GLU I  83
 None
 1.11A 5g0pA-5wduI:
undetectable
5g0pB-5wduI:
undetectable		 5g0pA-5wduI:
11.91
5g0pB-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 GLU I  83
VAL I 106
ARG I  61
VAL I  19
 None
 1.18A 5g0pA-5wduI:
undetectable
5g0pB-5wduI:
undetectable		 5g0pA-5wduI:
11.91
5g0pB-5wduI:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6C_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		3 / 3 ARG G 350
THR G 394
TRP G 395
 None
 1.28A 5g6cA-5wduG:
undetectable		 5g6cA-5wduG:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		3 / 3 GLY G 367
ASP G 368
ASN G 425
 None
 0.51A 5jglA-5wduG:
undetectable		 5jglA-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 12 LEU G 454
GLY G 471
GLY G 472
GLN G 258
VAL G 371
 None
 0.76A 5uc1A-5wduG:
undetectable		 5uc1A-5wduG:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 12 LEU G 454
GLY G 471
GLY G 472
GLN G 258
VAL G 371
 None
 0.81A 5uc1B-5wduG:
undetectable		 5uc1B-5wduG:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_1
(CYTOCHROME P450 3A4)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 12 PHE G 176
PHE G 159
ILE G 307
ALA G 316
ALA G 204
 None
 1.07A 5vceA-5wduG:
undetectable		 5vceA-5wduG:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW4_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 9 SER G 481
THR G 450
GLY G 451
LEU G 261
SER G 256
 None
None
None
NAG  G 627 ( 4.8A)
None
 1.19A 5vw4A-5wduG:
undetectable		 5vw4A-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		3 / 3 ARG I  54
ILE I  58
SER I  59
 None
 0.55A 5zw2A-5wduI:
undetectable		 5zw2A-5wduI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_B_SAMB401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 5wdu BNAB 35O22 FAB LIGHT
CHAIN
(Homo
sapiens) 		5 / 12 TYR I  86
GLY I  64
SER I   7
VAL I  11
VAL I  19
 None
 1.04A 6bxlB-5wduI:
undetectable		 6bxlB-5wduI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_A_BEZA701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 11 GLY G 451
LEU G 454
TRP G 338
PHE G 288
PHE G 391
 None
 1.24A 6qgbA-5wduG:
undetectable		 6qgbA-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_B_BEZB802_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 10 GLY G 451
LEU G 454
TRP G 338
PHE G 288
PHE G 391
 None
 1.24A 6qgbB-5wduG:
undetectable		 6qgbB-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_C_BEZC701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 9 GLY G 451
LEU G 454
TRP G 338
PHE G 288
PHE G 391
 None
 1.20A 6qgbC-5wduG:
undetectable		 6qgbC-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_D_BEZD701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 10 GLY G 451
LEU G 454
TRP G 338
PHE G 288
PHE G 391
 None
 1.23A 6qgbD-5wduG:
undetectable		 6qgbD-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_E_BEZE701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 11 GLY G 451
LEU G 454
TRP G 338
PHE G 288
PHE G 391
 None
 1.23A 6qgbE-5wduG:
undetectable		 6qgbE-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_F_BEZF701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 5wdu ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 10 GLY G 451
LEU G 454
TRP G 338
PHE G 288
PHE G 391
 None
 1.25A 6qgbF-5wduG:
undetectable		 6qgbF-5wduG:
undetectable