SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wee'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VPO_H_TESH1010_1 (ANTI-TESTOSTERONE (HEAVY CHAIN) ANTI-TESTOSTERONE (LIGHT CHAIN))	5wee	VENOM ALLERGEN LIKE PROTEIN 4 (Heligmosomoides polygyrus)	5 / 12	TYR A 80 ALA A 96 GLY A 95 LEU A 98 PHE A 19	None	1.30A	1vpoH-5weeA: undetectable 1vpoL-5weeA: undetectable	1vpoH-5weeA: 14.42 1vpoL-5weeA: 17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DTT_C_H4BC1002_1 (HYPOTHETICAL PROTEIN PH0634)	5wee	VENOM ALLERGEN LIKE PROTEIN 4 (Heligmosomoides polygyrus)	4 / 6	ASP A 25 PHE A 22 THR A 102 GLU A 99	None	1.19A	2dttB-5weeA: undetectable 2dttC-5weeA: undetectable	2dttB-5weeA: 19.20 2dttC-5weeA: 19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XO7_B_ASDB402_1 (ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2)	5wee	VENOM ALLERGEN LIKE PROTEIN 4 (Heligmosomoides polygyrus)	4 / 7	TYR A 152 ILE A 65 HIS A 23 LEU A 98	None	1.22A	4xo7B-5weeA: undetectable	4xo7B-5weeA: 13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AK3_A_P2EA1201_0 (PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE,SOLUBLE CYTOCHROME B562)	5wee	VENOM ALLERGEN LIKE PROTEIN 4 (Heligmosomoides polygyrus)	5 / 12	GLN A 123 THR A 97 VAL A 94 TYR A 139 THR A 15	None	1.40A	6ak3A-5weeA: undetectable	6ak3A-5weeA: 21.35

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1VPO_H_TESH1010_1","ANTI-TESTOSTERONE (HEAVY CHAIN);ANTI-TESTOSTERONE (LIGHT CHAIN)","5wee","VENOM ALLERGEN LIKE PROTEIN 4","Heligmosomoides polygyrus",5,"TYR A  80;ALA A  96;GLY A  95;LEU A  98;PHE A  19","None","1.30A","1vpoH-5weeA:undetectable;1vpoL-5weeA:undetectable","1vpoH-5weeA:14.42;1vpoL-5weeA:17.68"],["2DTT_C_H4BC1002_1","HYPOTHETICAL PROTEIN PH0634;HYPOTHETICAL PROTEIN PH0634","5wee","VENOM ALLERGEN LIKE PROTEIN 4","Heligmosomoides polygyrus",4,"ASP A  25;PHE A  22;THR A 102;GLU A  99","None","1.19A","2dttB-5weeA:undetectable;2dttC-5weeA:undetectable","2dttB-5weeA:19.20;2dttC-5weeA:19.20"],["4XO7_B_ASDB402_1","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2","5wee","VENOM ALLERGEN LIKE PROTEIN 4","Heligmosomoides polygyrus",4,"TYR A 152;ILE A  65;HIS A  23;LEU A  98","None","1.22A","4xo7B-5weeA:undetectable","4xo7B-5weeA:13.89"],["6AK3_A_P2EA1201_0","PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE,SOLUBLE CYTOCHROME B562","5wee","VENOM ALLERGEN LIKE PROTEIN 4","Heligmosomoides polygyrus",5,"GLN A 123;THR A  97;VAL A  94;TYR A 139;THR A  15","None","1.40A","6ak3A-5weeA:undetectable","6ak3A-5weeA:21.35"]]